B Cell News and Research

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SARS-CoV-2 RBD is a selective integrin agonist

Researchers assess the Arg-Gly-Asp (RGD) motif-mediated binding of the SARS-CoV-2 RBD and integrin receptors.

18 Apr 2022

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Researchers demonstrate that avasimibe-mediated inhibition of ACAT blocks the entry and fusion of SARS-CoV-2 in different cell types.

18 Apr 2022

Manipulating a specific gene from yeast could lead a new approach to combatting drug resistance

A recent study that shows manipulating and deleting a specific gene (AMN1) from yeast could provide a foundation for a new approach to combatting drug resistance when treating microbial infections or cancer.

18 Apr 2022

New insight into lymphoid cell maturity could pave the way for more effective IBD treatments

A research group at Karolinska Institutet in Sweden has analyzed how certain immune cells known as innate lymphoid cells (ILCs) develop into mature cells that play a part in inflammatory bowel disease (IBD).

15 Apr 2022

Scientists investigate how gut bacteria directly control the activity of specific neurons

Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions.

15 Apr 2022

Role of cGAS-STING in SARS-CoV-2 infection

A new study analyzes the activation of cGAS and STING can induce a type I IFN response due to SARS-CoV-2 infection.

15 Apr 2022

Durable neutralizing response against Omicron after heterologous vaccine boosting

Researchers assess the impact of homologous and heterologous primary-booster vaccine dose combinations.

15 Apr 2022

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

Researchers investigated the longevity and intensity of the SARS-CoV-2 vaccine immune response in patients suffering from immune-mediated inflammatory diseases.

15 Apr 2022

A comprehensive rule book for the design of safe and efficient therapeutic cells

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

15 Apr 2022

Breakthrough finding reveals how male sex hormones contribute to cancer-related sex bias

Patients with cancers stemming from non-reproductive organs, such as bladder and liver cancer, have striking discrepancies in incidence, progression, response to treatment and survival outcomes depending on their sex. In almost all cases, male patients have worse prognoses and outcomes.

15 Apr 2022

Comparison of neutralizing antibody response following SARS-CoV-2 booster vaccination with breakthrough infection

A new study examined the serological immune responses and antibody-dependent cell-mediated phagocytosis in individuals who had either received two doses of a standard vaccine regime, a booster dose following the regime, or a breakthrough infection following vaccination.

15 Apr 2022

Insight into the future of genetic testing

In this interview, we speak to Sheetal Parmar, vice president of medical affairs and head of clinical services at Natera, about their cell-free DNA (cfDNA) testing services.

From Natera 15 Apr 2022

Effects of COVID-19 treatment best with combination therapy

There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms of action of antiviral and anti-inflammatory drugs.

15 Apr 2022

Cell’s production of lipids can be a key factor in determining cell fate

How does a cell "decide" what type of cell to become? The question of "cell fate" has been explored for decades now, especially in the context of stem cell biology, but there are still gaps in our understanding.

15 Apr 2022

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill Cornell Medicine investigators.

14 Apr 2022

Yale research demonstrates the cancer relevance of known human genes

Following an analysis of over 12,000 human genes, research from Yale Cancer Center indicates there is cancer-relevant importance in a much larger proportion of human genes than current cancer research models suggest.

14 Apr 2022

Scientists discover differences in interaction of T-cells within tumor microenvironments

A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according to findings published in the journal JCI Insight.

14 Apr 2022

B Cell News and Research

SARS-CoV-2 RBD is a selective integrin agonist

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Manipulating a specific gene from yeast could lead a new approach to combatting drug resistance

New insight into lymphoid cell maturity could pave the way for more effective IBD treatments

Scientists investigate how gut bacteria directly control the activity of specific neurons

Role of cGAS-STING in SARS-CoV-2 infection

Durable neutralizing response against Omicron after heterologous vaccine boosting

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

A comprehensive rule book for the design of safe and efficient therapeutic cells

Breakthrough finding reveals how male sex hormones contribute to cancer-related sex bias

Comparison of neutralizing antibody response following SARS-CoV-2 booster vaccination with breakthrough infection

Insight into the future of genetic testing

Effects of COVID-19 treatment best with combination therapy

Cell’s production of lipids can be a key factor in determining cell fate

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Yale research demonstrates the cancer relevance of known human genes

Scientists discover differences in interaction of T-cells within tumor microenvironments

New data-driven mechanistic approach can help reduce drug costs and treat diseases

Exploring strategies for successful delivery of messenger RNA therapeutics

Recent advances in non-viral nano-vector delivery of CRISPR/Cas9 genome editing payloads

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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