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Merck reports strong bottom-line performance in second quarter

Merck & Co., Inc. today announced financial results for the second quarter of 2010. The company reported non-GAAP (generally accepted accounting principles) earnings per share (EPS) for the second quarter of $0.86, which excludes purchase accounting adjustments, merger-related expenses, restructuring costs and the gain on AstraZeneca's asset option exercise. Second-quarter GAAP EPS was $0.24.

2 Aug 2010

FDA lifts hold, allows Geron to proceed with Phase I clinical trial of GRNOPC1 in spinal cord injury

Geron Corporation announced today that the U.S. Food and Drug Administration (FDA) has notified the company that the clinical hold placed on Geron's Investigational New Drug (IND) application has been lifted and the company's Phase I clinical trial of GRNOPC1 in patients with acute spinal cord injury may proceed.

30 Jul 2010

Researchers find new pathway that leads to brain cell death in neurodegenerative disorders

Although their genetic underpinnings differ, Alzheimer's disease, Parkinson's disease and Huntington's disease are all characterized by the untimely death of brain cells. What triggers cell death in the brain? According to a new study published by researchers at Sanford-Burnham Medical Research Institute in the July 30 issue of Molecular Cell, the answer in some cases is the untimely transfer of a gaseous molecule (known as nitric oxide, or NO) from one protein to another.

30 Jul 2010

Research to help people born with 'face blindness'

A specific area in our brains is responsible for processing information about human and animal faces, both how we recognize them and how we interpret facial expressions. Now, Tel Aviv University research is exploring what makes this highly specialized part of the brain unique, a first step to finding practical applications for that information.

29 Jul 2010

MedTera, HealthPrize Technologies partner to help patients self-manage their diseases

MedTera, an integrated marketing solutions company dedicated to improving education, promotion and communications in the healthcare, life sciences and pharmaceutical industries, today announced its formal partnership with HealthPrize Technologies, a web-based software company that motivates people to fill and stay on prescription medications.

29 Jul 2010

Genetic signals determine neurotransmitter use for communication

Cascades of genetic signals determine which neurotransmitter a brain cell will ultimately use to communicate with other cells. Now a pair of reports from biologists at the University of California, San Diego, have shown for the first time that electrical activity in these developing neurons can alter their chemical fate-and change an animal's behavior-by tweaking this genetic program.

29 Jul 2010

FDA Advisory Committee recommends approval of AstraZeneca's ticagrelor for Acute Coronary Syndromes

AstraZeneca today announced that the US Food and Drug Administration Cardiovascular and Renal Drugs Advisory Committee recommended the FDA approve AstraZeneca's investigational drug ticagrelor for the reduction of thrombotic events in patients with Acute Coronary Syndromes.

29 Jul 2010

REM sleep behavior disorder may later lead to neurologic disorders

A new study shows that a sleep disorder may be a sign of dementia or Parkinson's disease up to 50 years before the disorders are diagnosed. The research is published in the July 28, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Jul 2010

NIH grants $14.85 million to complete two floors of NRI at Texas Children's Hospital

Neurological research at Baylor College of Medicine and Texas Children's Hospital is getting a big boost in the form of a $14.85 million grant from the National Institutes of Health to complete two floors of the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital.

29 Jul 2010

Increased SIRT1 protein can delay delay aging, extend lifespan

Researchers watched two groups of mice, both nearing the end of a two-day fast. One group was quietly huddled together, but the other group was active and alert. The difference? The second set of mice had been engineered so their brains produced more SIRT1, a protein known to play a role in aging and longevity.

29 Jul 2010

The neck played major role in evolution of human brain: Study

By deciphering the genetics in humans and fish, scientists now believe that the neck - that little body part between your head and shoulders - gave humans so much freedom of movement that it played a surprising and major role in the evolution of the human brain, according to New York University and Cornell University neuroscientists in the online journal Nature Communications (July 27, 2010.)

28 Jul 2010

Experts to discuss treatment options for wounded warriors at USU-HJF Military Medicine Symposium

The USU-HJF Military Medicine Symposium will gather prominent civilian and military researchers and clinicians from across the United States to discuss current research and identify opportunities to collaborate and share information that could speed treatments to wounded warriors. The symposium also will bring together a broad spectrum of participants from military health leadership, federal agencies and private research institutions to philanthropists and charitable foundations, representatives of industry, and policymakers.

28 Jul 2010

Astellas extends non-exclusive license agreement with Regeneron for VelocImmune technology

Regeneron Pharmaceuticals, Inc. and Astellas Pharma Inc. announced that Astellas has extended through 2023 the non-exclusive license agreement that allows Astellas to utilize Regeneron's VelocImmune® technology in its internal research programs to discover fully human monoclonal antibody product candidates.

28 Jul 2010

Lenzenweger releases book for schizophrenia

About 1 in 10 people have the potential to develop schizophrenia, but only 1 in 100 actually end up with this devastating illness. The challenge is in knowing why some do and some don't.Drawing from over 25 years of laboratory study, Mark F. Lenzenweger, a distinguished professor of clinical science, neuroscience and cognitive psychology at Binghamton University, thinks that not only does he have the makings of a good response to this troubling question but also how to go about finding those answers.

27 Jul 2010

Psychologists to host China's first-ever conference on positive psychology

The ranks of China's millionaires continue to grow, but the increased wealth has done little to boost the country's gross domestic happiness, according to psychologists at the University of California, Berkeley. They say the pursuit of prosperity in the nation is fast outpacing mental health and well-being, and are seeking to correct that imbalance by spreading the science of happiness in China.

27 Jul 2010

Albert Einstein College of Medicine receives research grant to help people with MDR-TB

For the third time in four months, the National Institute of Allergy and Infectious Diseases of the National Institutes of Health has awarded Albert Einstein College of Medicine of Yeshiva University a research grant aimed at helping people infected with multidrug-resistant tuberculosis. Taken together, all three NIH grants total $8.57 million.

27 Jul 2010

Epilepsy drugs analyzed for causing increased risk of suicide in patients

While the Food and Drug Administration requires a warning of an increased risk of suicide for all epilepsy drugs, a new study shows that only certain drugs may increase the risk. The study is published in the July 27, 2010, issue of Neurology, the medical journal of the American Academy of Neurology. Newer drugs with a higher risk of causing depression than other epilepsy drugs, such as levetiracetam, topiramate and vigabatrin, were found to increase the risk of self-harm or suicidal behavior among people with epilepsy.

27 Jul 2010

Seaside Therapeutics reports positive data from STX209 Phase 2 study in fragile X syndrome

Seaside Therapeutics, Inc. announced today data from the largest randomized, placebo-controlled study conducted to date in individuals with fragile X syndrome. In a Phase 2 study of STX209, clinically meaningful improvements on global and specific neurobehavioral outcomes were observed in the general study population. The improvements were statistically significant in pediatric patients with more severe impairments in sociability -- a core symptom of fragile X syndrome.

26 Jul 2010

Research reveals molecular basis of neural circuits

The basal ganglia is a series of highly connected brain areas localised deep in the cerebral cortex that recently has attracted interest of neuroscientists when it was linked to learning, and discovered to be affected in a number of disorders of the addictive and obsessive spectrum, but also in Parkinson's disease (PD). And now researchers think they have understood why as they found that neurons in this area signal the beginning and the end of voluntary actions. In fact, problems in these neurons could explain the "incapacity to stop" seen in obsession or compulsive behaviour, but also the problems in learning and control of movement characteristic of Parkinson's

26 Jul 2010

Diagnostic guidelines for arthritis-related back pain result in excessive tests, delay in pain relief: Research

Slavishly following long-held guidelines for diagnosing the cause of arthritis-related back pain is resulting in excessive tests, delays in pain relief and wasteful spending of as much as $10,000 per patient, new Johns Hopkins-led research suggests.

26 Jul 2010

Neuroscience News and Research

Merck reports strong bottom-line performance in second quarter

FDA lifts hold, allows Geron to proceed with Phase I clinical trial of GRNOPC1 in spinal cord injury

Researchers find new pathway that leads to brain cell death in neurodegenerative disorders

Research to help people born with 'face blindness'

MedTera, HealthPrize Technologies partner to help patients self-manage their diseases

Genetic signals determine neurotransmitter use for communication

FDA Advisory Committee recommends approval of AstraZeneca's ticagrelor for Acute Coronary Syndromes

REM sleep behavior disorder may later lead to neurologic disorders

NIH grants $14.85 million to complete two floors of NRI at Texas Children's Hospital

Increased SIRT1 protein can delay delay aging, extend lifespan

The neck played major role in evolution of human brain: Study

Experts to discuss treatment options for wounded warriors at USU-HJF Military Medicine Symposium

Astellas extends non-exclusive license agreement with Regeneron for VelocImmune technology

Lenzenweger releases book for schizophrenia

Psychologists to host China's first-ever conference on positive psychology

Albert Einstein College of Medicine receives research grant to help people with MDR-TB

Epilepsy drugs analyzed for causing increased risk of suicide in patients

Seaside Therapeutics reports positive data from STX209 Phase 2 study in fragile X syndrome

Research reveals molecular basis of neural circuits

Diagnostic guidelines for arthritis-related back pain result in excessive tests, delay in pain relief: Research

Event guide: 8th Neuroimmunology Drug Development Summit 2026 eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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