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Novel drug could enable the immune system to attack ovarian cancer

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Researchers develop novel tool to maximize the power of deep learning for genomic studies

Researchers from the MDC have developed a new tool that makes it easier to maximize the power of deep learning for studying genomics.

13 Jul 2020

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

Researchers at the University of East Anglia and University of Manchester have made an important breakthrough that could lead to ‘kinder’ treatments for children with bone cancer, and save lives.

13 Jul 2020

New biomarker could be an early indicator of cognitive decline

Medical researchers in the UK and Australia have identified a new marker which could support the search for novel preventative and therapeutic treatments for dementia.

11 Jul 2020

USC scientists may have found a path toward increasing human lifespan

Scientists at USC Dornsife College of Letters, Arts and Sciences may have found the beginnings of a path toward increasing human lifespan.

11 Jul 2020

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

11 Jul 2020

Establishment of global surveillance network can warn about next pandemic

The virus that causes COVID-19 probably originated in wild bats that live in caves around Wuhan, China, and may have been passed to a second animal species before infecting people, according to the World Health Organization.

10 Jul 2020

Study could help determine motor abilities that are difficult to recover after traumatic brain injury

After a traumatic brain injury, why do some people quickly regain their skills while others face long-lasting setbacks? Boston University neuroscientist Jerry Chen and his colleagues have been trying to answer this question by understanding which parts of the brain are used to process sensory information and remember different skills.

10 Jul 2020

Study discusses four possible scenarios for growth of aquaculture in the COVID-19 era

Aquaculture, the relatively young but fast-growing industry of farming of fish and other marine life, now produces around half of all seafood consumed by humans.

10 Jul 2020

Rat plague following COVID-19?

The COVID-19 pandemic led to the widespread closure of many business establishments, including eateries and restaurants. This kind of mass change in human behavior has historically led to changes in animal behavior as well. This is especially observed with respect to urban rat behavior.

9 Jul 2020

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Activating the immune system of the body is a promising form of treatment for cancer. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient groups which could potentially benefit from immunotherapies.

9 Jul 2020

Overzealous guardians in the cells could increase cancer risk

Researchers at the UiO and OUS have discovered how destructive changes occur in our genome. This could lead to cancer. Their results have been published in the journal Nature Cell Biology.

9 Jul 2020

DNA hypermethylation correlated with reduced amygdala volume in male patients with schizophrenia

Researchers at Kumamoto University, Japan have revealed that DNA methylation occurs in the gene that codes serotonin transporter (SERT), a protein that regulates neurotransmitter transmission, in schizophrenia and bipolar patients.

9 Jul 2020

Breast cancer cells can reprogram natural killer cells to aid in metastasis

Natural killer cells, a type of immune cell, are known to limit metastasis by inducing the death of cancer cells. But metastases still form in patients, so there must be ways for cancer cells to escape.

9 Jul 2020

Groundbreaking study identifies unique lung cells that may drive pulmonary fibrosis

A groundbreaking study published today and led by the Translational Genomics Research Institute, an affiliate of City of Hope, identifies unique lung cells that may drive Idiopathic Pulmonary Fibrosis, a deadly lung disease that affects hundreds of thousands of Americans, and for which there is no cure.

9 Jul 2020

Genomics can perpetuate inequality and structural racism

Genomics is crowding out ways of reducing inequality, has thwarted medicine from advancing justice, and is creating new forms of social classification and surveillance.

9 Jul 2020

Ozone gas can provide a safe means to disinfect personal protective equipment

A new study shows that ozone gas, a highly reactive chemical composed of three oxygen atoms, could provide a safe means for disinfecting certain types of personal protective equipment that are in high demand for shielding health care personnel from Covid-19.

9 Jul 2020

Experimental drug for rare ALS shows promise in early clinical trial

An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine in St. Louis, Massachusetts General Hospital in Boston and other sites around the world and sponsored by the pharmaceutical company Biogen Inc.

8 Jul 2020

Tracing adaptation to ACE2 use in sarbecoviruses

A detailed study published on the preprint server bioRxiv in July 2020 argues that recombination accounts for the appearance of the ability of both SARS-CoV and SARS-CoV-2 to use the human angiotensin-converting enzyme (hACE) 2 as the binding receptor mediating viral infection of human cells.

8 Jul 2020

Research sheds doubt on the Pangolin link to SARS-CoV-2

A startling new study by researchers at the Broad Institute of MIT and the University of British Columbia and published on the preprint server bioRxiv* in July 2020 casts doubt on the hypothesis that the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was transmitted from pangolins acting as the intermediate host. Instead, the authors suggest, the pangolins themselves were incidentally infected from other animals in captivity or from humans.

8 Jul 2020

Genetic News and Research

Novel drug could enable the immune system to attack ovarian cancer

Researchers develop novel tool to maximize the power of deep learning for genomic studies

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

New biomarker could be an early indicator of cognitive decline

USC scientists may have found a path toward increasing human lifespan

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Establishment of global surveillance network can warn about next pandemic

Study could help determine motor abilities that are difficult to recover after traumatic brain injury

Study discusses four possible scenarios for growth of aquaculture in the COVID-19 era

Rat plague following COVID-19?

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Overzealous guardians in the cells could increase cancer risk

DNA hypermethylation correlated with reduced amygdala volume in male patients with schizophrenia

Breast cancer cells can reprogram natural killer cells to aid in metastasis

Groundbreaking study identifies unique lung cells that may drive pulmonary fibrosis

Genomics can perpetuate inequality and structural racism

Ozone gas can provide a safe means to disinfect personal protective equipment

Experimental drug for rare ALS shows promise in early clinical trial

Tracing adaptation to ACE2 use in sarbecoviruses

Research sheds doubt on the Pangolin link to SARS-CoV-2

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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