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Human coronaviruses need organic materials to transfer efficiently between surfaces

This study, published in the journal Viruses, indicated that human coronaviruses do not transfer effectively from contaminated hands to contact surfaces without the presence of any organic material.

21 Jul 2021

Study finds dramatic decreases in antibiotic dispensing for children during the pandemic

As children made fewer visits to health facilities and engaged in social distancing and other COVID-19 mitigation measures, a smaller number of them also received prescription drugs, a new study suggests.

20 Jul 2021

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

The ongoing coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 190 million cases worldwide. Of these, over 4 million have died due to the infection.

20 Jul 2021

T cells can be engineered to fight tumors without succumbing to exhaustion

Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion.

19 Jul 2021

Do mRNA-based COVID-19 vaccines induce memory T cell response similar to natural infection?

A team of scientists from the United States has recently compared the epitope-specific T cell response after natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or vaccination in both naïve and previously infected individuals.

19 Jul 2021

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

Researchers in the United States have designed a modular protein subunit vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that elicited a strong immune response in macaques and prevented the animals from developing coronavirus disease 2019 (COVID-19).

15 Jul 2021

Pandemic of antibiotic resistance is shortening the lives of children in Bangladesh

Resistance to antibiotics is common and often deadly among children with pneumonia in Bangladesh, according to a new study coauthored by researchers from Massachusetts General Hospital (MGH) with colleagues at the International Centre for Diarrhoeal Disease Research, Bangladesh (abbreviated as icddr,b).

15 Jul 2021

Understanding the molecular mechanisms behind lung cancer relapse

When a doctor gives a patient antibiotics for a bacterial infection, they usually require them to finish the entire treatment, even when symptoms go away.

13 Jul 2021

Colonization by SARS-CoV-2 not synonymous with infection, screening study highlights

A new study released as a preprint on the medRxiv* server throws cold water on this notion, however, by demonstrating that in a set of asymptomatic cases, less than a tenth actually had evidence of SARS-CoV-2 infection. This finding has serious implications for the practices mentioned above, since they may be neither justifiable nor cost-effective as means to break the chain of viral transmission.

13 Jul 2021

Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

A team of scientists from France has recently demonstrated photosensitive antiviral activity of the natural compound pheophorbide a (Pba) against a broad range of enveloped viruses, including coronaviruses.

12 Jul 2021

Asia accounts for more than half of global temperature-related deaths, study finds

Asia accounts for more than half of the over five million global deaths attributed to ambient cold and hot temperatures, according to an international study. But many governments are failing to prioritize health in their climate change strategies, experts warn.

12 Jul 2021

Novel cold-tolerant bacterium produces a red bio-pigment with germ-killing properties

A team of researchers from Shoolini University, Himachal Pradesh, India have discovered a psychrophilic bacterial strain, called Rhodonellum psychrophilum GL8, at the high altitude Pangong Tso Lake in the Himalayas.

12 Jul 2021

Accelerating the design of minibinder therapeutics resilient to SARS-CoV-2 mutations

Multivalent protein-based minibinders hold great promise as potential prophylactic and treatment agents, as they can retain their activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern. This was revealed in a recent tour-de-force research study currently available on the bioRxiv* preprint server while the article undergoes the peer review process.

11 Jul 2021

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

A new study from Queen Mary University of London has demonstrated that immune cells can be stimulated to assemble into special structures within pancreatic cancer such that, at least in a pre-clinical model, researchers can demonstrate an improvement in the efficacy of chemotherapy.

9 Jul 2021

Why is the SARS-CoV-2 Delta variant so concerning?

As cases surge in the United States, health experts have raised the alarm that vaccinated individuals may be spreading the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant. Over half of new infections in the U.S. are now caused by this highly transmissible variant.

9 Jul 2021

Intranasal COVID-19 vaccine protects animals against lethal COVID-19 infection

In a new study assessing the potential of a single-dose, intranasal COVID-19 vaccine, a team from the University of Iowa and the University of Georgia found that the vaccine fully protects mice against lethal COVID-19 infection.

8 Jul 2021

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

In a recent study published in the journal Science Immunology, scientists have revealed that the presence of CD8+ T cells against conserved epitopes of seasonal coronaviruses is associated with mild coronavirus disease 2019 (COVID-19). These immune cells exhibit a memory phenotype and provide protection against severe disease.

7 Jul 2021

Cold News and Research

Human coronaviruses need organic materials to transfer efficiently between surfaces

Study finds dramatic decreases in antibiotic dispensing for children during the pandemic

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

T cells can be engineered to fight tumors without succumbing to exhaustion

Do mRNA-based COVID-19 vaccines induce memory T cell response similar to natural infection?

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

Pandemic of antibiotic resistance is shortening the lives of children in Bangladesh

Understanding the molecular mechanisms behind lung cancer relapse

Colonization by SARS-CoV-2 not synonymous with infection, screening study highlights

Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

Asia accounts for more than half of global temperature-related deaths, study finds

Novel cold-tolerant bacterium produces a red bio-pigment with germ-killing properties

Accelerating the design of minibinder therapeutics resilient to SARS-CoV-2 mutations

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

Why is the SARS-CoV-2 Delta variant so concerning?

Intranasal COVID-19 vaccine protects animals against lethal COVID-19 infection

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

Plant compounds inhibit Mpro of SARS-CoV-2 and HCoV-229E in vitro

Castration of male sheep slows DNA aging

Developing a face mask that can detect COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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