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New computer models could help researchers to better predict side-effects of drugs

New computer models from North Carolina State University show how a variant of a common protein involved in human immune response binds to the antiviral drug abacavir, causing a severe life-threatening reaction known as the abacavir hypersensitivity syndrome

8 Mar 2017

Penn researchers identify genome-wide changes caused by high-fat diet

By comparing two strains of mice -- one that becomes obese and diabetic on a high-fat diet and another resistant to a high-fat regimen -- researchers from the Perelman School of Medicine at the University of Pennsylvania identified genome-wide changes caused by a high-fat diet.

8 Mar 2017

Early treatment with heart failure drug can improve cardiac function in young boys with DMD

Researchers at The Ohio State University Ross Heart Hospital and Nationwide Children's Hospital have shown early treatment with the heart failure medication eplerenone can improve heart function in young boys with Duchenne muscular dystrophy (DMD) and stabilize heart function in older boys with the disease.

7 Mar 2017

Study reveals promising new strategy to attack deadly pediatric brain tumor

Researchers from Northwestern Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago have revealed new insight into how the most deadly pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG), may develop.

7 Mar 2017

Researchers identify key mutation that promotes melanoma growth by suppressing immune response

University of California, Irvine researchers have identified a specific mutation that allows melanoma tumor cells to remain undetected by the immune system.

7 Mar 2017

UCI chemists develop cheap, effective way to neutralize deadly snake venom

Chemists at the University of California, Irvine have developed a way to neutralize deadly snake venom more cheaply and effectively than with traditional anti-venom -- an innovation that could spare millions of people the loss of life or limbs each year.

7 Mar 2017

Researchers identify protein biomarker linked to prognosis in high-grade serous ovarian cancer

Ovarian cancer researchers have identified a protein biomarker expressed on the surface of tumour cells in high-grade serous ovarian cancer, the most common and lethal subtype of the disease.

7 Mar 2017

Researchers show how composition of mitochondrial calcium portal differs based on organs

A heart beat begins with a rush of calcium into the heart cell followed by a burst of energy from the resident mitochondria. These two events occur with each beat.

7 Mar 2017

IU study reveals new compounds with potential to boost enzyme that could protect against dementia

A study by Indiana University researchers has identified 24 compounds -- including caffeine -- with the potential to boost an enzyme in the brain shown to protect against dementia.

7 Mar 2017

Research findings could guide development of potent combination therapies for leukemia

New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia.

7 Mar 2017

Low carbohydrate diet may be effective strategy for managing diabetes, research suggests

Following a reduced carbohydrate diet can help to lower blood glucose levels, providing a safe and effective strategy for managing diabetes, new research by London Metropolitan University suggests.

7 Mar 2017

New research program aims to produce all human secreted proteins

A new research program has been launched to produce all the human secreted proteins in mammalian cell factories. The program aims to facilitate studies of this important class of proteins, which are involved in many human diseases.

7 Mar 2017

Researchers reveal how overloading of protein transport mechanisms triggers cellular defects

Researchers at Okayama University report in Scientific Reports how the overloading of protein transport mechanisms affects cell functioning. Over-expression of different types of target proteins leads to cellular growth defects, and the mechanism for transporting proteins out of a cell nucleus has the lowest over-expression tolerance.

7 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

Using red blood cells modified to carry disease-specific antigens, scientists in the laboratories of Hidde Ploegh and Harvey Lodish have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.

7 Mar 2017

TSRI scientists discover how key protein establishes proper vision

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G Protein News and Research

New computer models could help researchers to better predict side-effects of drugs

Penn researchers identify genome-wide changes caused by high-fat diet

Early treatment with heart failure drug can improve cardiac function in young boys with DMD

Study reveals promising new strategy to attack deadly pediatric brain tumor

Researchers identify key mutation that promotes melanoma growth by suppressing immune response

UCI chemists develop cheap, effective way to neutralize deadly snake venom

Researchers identify protein biomarker linked to prognosis in high-grade serous ovarian cancer

Researchers show how composition of mitochondrial calcium portal differs based on organs

IU study reveals new compounds with potential to boost enzyme that could protect against dementia

Research findings could guide development of potent combination therapies for leukemia

Low carbohydrate diet may be effective strategy for managing diabetes, research suggests

New research program aims to produce all human secreted proteins

Researchers reveal how overloading of protein transport mechanisms triggers cellular defects

New drug-like compound shows potential to treat symptoms of lupus

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

TSRI scientists discover how key protein establishes proper vision

Study identifies protein that may offer protection against heart disease

Head injuries can harm hundreds of genes to increase risk for severe brain disorders

Researchers uncover new genetic clues linked to autoimmune kidney disease

SLU study findings suggest new method to suppress LDL cholesterol

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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