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Low-dose direct oral anticoagulants linked to increased bleeding risk in Afib patients

Patients with atrial fibrillation (Afib) who took low doses of blood-thinning medications known as direct oral anticoagulants (DOACs) experienced more bleeding episodes during the first three months of treatment and about one in five had high blood levels of the medications, compared with similar patients who took standard doses of the same medications, according to a study published in Blood Advances.

6 Jun 2024

Injectable fish oil emulsion reduces brain damage in newborn rodents

An injectable emulsion containing two omega-3 fatty acids found in fish oil markedly reduced brain damage in newborn rodents after a disruption in the flow of oxygen to the brain near birth, a study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

6 Jun 2024

Higher amounts of sugar alcohol xylitol associated with increased risk of cardiovascular events

Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.

6 Jun 2024

Oral insulin drops offer needle-free alternative for diabetes management

Diabetes rates continue to rise, with 11.7 million Canadians living with diabetes or pre-diabetes. At UBC, scientists have created a pain-free drug delivery method to help people with diabetes manage the disease and maintain their health more easily.

5 Jun 2024

Goethe University Frankfurt's Student Polyclinic marks its tenth anniversary

On June 3, Goethe University Frankfurt's Student Polyclinic, part of the Frankfurt Health Department, marked its tenth anniversary.

5 Jun 2024

Common anti-inflammatory drug could combat deadly gut fungus, study finds

A team of UC Davis Health researchers discovered that a common anti-inflammatory drug, mesalamine, can replace the work of good bacteria in fighting the nasty fungus Candida albicans in the gut.

4 Jun 2024

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

The combination of the antibody amivantamab and lazertinib, a drug targeting EGFR, shows better clinical benefits compared to standard treatment in patients with advanced or metastatic non-small cell lung cancer with EGFR gene mutations who also present one of these poor prognosti markers: brain and/or liver metastases, p53 gene co-mutations, or the presence of circulating tumor DNA.

4 Jun 2024

Novel small molecule oral antiviral could be a game-changer in the fight against future pandemics

Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics.

4 Jun 2024

Discovery of antibiotic lolamicin that targets deadly bacteria without harming gut microbiome

Researchers discovered lolamicin, a selective Gram-negative antibiotic, effective against multidrug-resistant pathogens while sparing the gut microbiome.

4 Jun 2024

Long-term study reveals safety of metformin use during pregnancy

Metformin is safe to use during pregnancy to manage diabetes, with no long-term adverse effects on the children born and their mothers for at least 11 years after childbirth, according to research presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Clinicians at Georgetown University's Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).

3 Jun 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Type 2 diabetes linked to higher cancer risk, especially with diabetic retinopathy, study finds

A recent study in BMC Medicine found that type 2 diabetes significantly increases the risk of various cancers, with the risk being even higher in patients with diabetic retinopathy (DR).

2 Jun 2024

Dana-Farber study exposes hidden disparities in cancer care experiences

Four teams of Dana-Farber Cancer Institute investigators have found that people experience discrimination and bias in different ways and in more realms of cancer care than previously understood.

30 May 2024

New AI tool analyzes medical history to match patients with best antidepressant

Researchers in George Mason University's College of Public Health have leveraged the power of artificial intelligence (AI) analytical models to match a patient's medical history to the most effective antidepressant, allowing patients to find symptom relief sooner.

30 May 2024

Mayo Clinic researchers uncover microbial signatures linked to gynecologic cancers

Early detection improves treatment outcomes for endometrial and ovarian cancers, yet far too often women are diagnosed in advanced stages of these diseases.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Oral semaglutide shows significant promise in improving diabetes control and cardiovascular health, study reveals

A recent study in the Journal of Clinical Medicine found that oral semaglutide significantly improves glycemic control and reduces body weight in type 2 diabetes patients after 24 weeks of treatment.

29 May 2024

Microplastics: Invisible to the eye but severely harmful to pregnancy and metabolic outcomes

The effects of polystyrene microplastics on pregnancy outcomes and glucose metabolism.

29 May 2024

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Oral News and Research

Low-dose direct oral anticoagulants linked to increased bleeding risk in Afib patients

Injectable fish oil emulsion reduces brain damage in newborn rodents

Higher amounts of sugar alcohol xylitol associated with increased risk of cardiovascular events

Oral insulin drops offer needle-free alternative for diabetes management

Goethe University Frankfurt's Student Polyclinic marks its tenth anniversary

Common anti-inflammatory drug could combat deadly gut fungus, study finds

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

Novel small molecule oral antiviral could be a game-changer in the fight against future pandemics

Discovery of antibiotic lolamicin that targets deadly bacteria without harming gut microbiome

Long-term study reveals safety of metformin use during pregnancy

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Type 2 diabetes linked to higher cancer risk, especially with diabetic retinopathy, study finds

Dana-Farber study exposes hidden disparities in cancer care experiences

New AI tool analyzes medical history to match patients with best antidepressant

Mayo Clinic researchers uncover microbial signatures linked to gynecologic cancers

Existing drug alleviates symptoms of a rare genetic syndrome

Oral semaglutide shows significant promise in improving diabetes control and cardiovascular health, study reveals

Microplastics: Invisible to the eye but severely harmful to pregnancy and metabolic outcomes

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

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