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SARS-CoV-2 spike S375F mutation triggered the explosive spread of Omicron

In a recent study posted to the bioRxiv* preprint server, researchers investigated the mutation in the viral spike (S) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 variant (referred to as Omicron in the present study) that is responsible for the variant’s virological features.

7 Apr 2022

Researchers discover over 40 new genetic markers for Alzheimer’s disease

A new Nature Genetics study describes over 70 gene markers that appear to be significantly associated with AD risk using translational genomics.

6 Apr 2022

New platform for studying how the immune system responds to hepatitis C

A vaccine for hepatitis C has eluded scientists for more than 30 years, for several reasons. For one, the virus that causes the disease comes in many genetic forms, complicating the creation of a widely effective vaccine.

6 Apr 2022

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients. The results are published in ACS Applied Materials and Interfaces.

6 Apr 2022

High-throughput screening assay could identify new prostate cancer drugs

A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer.

6 Apr 2022

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled receptors (GPCRs).

6 Apr 2022

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report in a new study.

6 Apr 2022

Study captures the immune effect of COVID-19 vaccine in patients with multiple myeloma

Most immunocompromised people with a blood cancer called multiple myeloma benefited from a third dose of COVID-19 vaccines, a promising sign after it was shown that two doses tended to not be sufficient for them.

6 Apr 2022

SEACells: an algorithm for identifying metacells

A new study has presented single-cell aggregation of cell-states (SEACells), a graph-based algorithm for identifying metacells.

6 Apr 2022

Insights into the pathophysiology of NeuroCOVID

A new study describes the neurological features of COVID-19, both short- and long-term.

6 Apr 2022

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Researchers characterized SARS-CoV-2 spike (S) isolates extracted from the samples of two individuals infected with the virus in Peru (ΔN25) and Brazil (ΔN135) in January 2021.

6 Apr 2022

Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques

Researchers investigated the effectiveness of a circRNA vaccine against SARS-CoV-2 and its Delta and Omicron variants, which elicited significant antibody and T-cell responses in mice and rhesus macaques.

6 Apr 2022

Developing and manufacturing custom recombinant antibodies for R&D

In this interview, Dr. Linlin Zhang, technical specialist for Sino Biological Europe, discusses how Sino is expanding its product offerings into the European market and outlines its process for developing and manufacturing custom recombinant antibodies for their clients.

From Sino Biological Inc. 6 Apr 2022