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New technique to sort out complex interactions unique to prostate cancer cells

UT Southwestern researchers have identified vast webs of small snippets of the genome that interact with each other and with genes to promote prostate cancer.

7 Jul 2020

DNA resection pathways are highly specific, shows study

Our cells are constantly dividing, and as they do, the DNA molecule - our genetic code - sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous.

7 Jul 2020

Study may lead to novel therapeutic targets in certain memory disorders

To make new memories, our brain cells first must find one another. Small protrusions that bud out from the ends of neurons' long, branching tentacles dock neurons together so they can talk.

7 Jul 2020

Study: Group genomics are responsible for aggression in Africanized honey bees

Researchers often study the genomes of individual organisms to try to tease out the relationship between genes and behavior.

7 Jul 2020

First microbiome study of Irish Travelers provides important new health insights

Investigators at APC Microbiome Ireland (http://apc.ucc.ie) SFI Research Centre in Cork were stunned by the findings of the first microbiome study of Irish Travellers which challenges the concept of a 'normal' or 'healthy' microbiome and asks: "what is a normal or desirable microbiome in an ethnically diverse society?"

6 Jul 2020

Work begins on UK-wide system for detecting coronavirus in wastewater

Scientists will develop a standardized UK-wide system for detecting coronavirus in wastewater, in order to provide an early warning of future outbreaks and reduce reliance on costly testing of large populations.

6 Jul 2020

Real-time tracking of protein filaments in the nuclear pore complex

In human cells, the nucleus is enclosed by a structure called the nuclear pore complex (NPC). It acts as a 'gatekeeper' controlling the transport of molecules between the nucleus and the surrounding cytoplasm (the protein-containing solution in the inside of a cell).

6 Jul 2020

Easy-to-use software developed to identify drug-resistant genes in bacteria

Washington State University researchers have developed an easy-to-use software program to identify drug-resistant genes in bacteria.

6 Jul 2020

New strategies can help increase the efficiency of artificial cell reprogramming

Maria-Elena: Can you imagine being able to artificially generate cells that can develop into any cell type? That would be really fantastic! We call this ability 'totipotency' and it is the highest level of cellular plasticity.

6 Jul 2020

Using machine learning to analyze the interaction of breast cancer risk factors

A recently published article from University of Eastern Finland and Kuopio University Hospital reports new innovative use of machine learning to help understand the interplay of genetic and other breast cancer risk factors.

6 Jul 2020

Oxford COVID-19 vaccine trials move to stage 3 human trials

The technical name of the vaccine is ChAdOx1 nCoV-19 (AZD1222), as it is made from a virus called ChAdOx1, which is a weakened and non-replicating version of a common cold virus (adenovirus). The vaccine has been engineered to express the SARS-CoV-2 spike protein.

5 Jul 2020

NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome, reveals study

An international research collaboration, including Professor IIJIMA Kazumoto et al. (of the Department of Pediatrics, Kobe University Graduate School of Medicine) has revealed that NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome in children.

3 Jul 2020

New editorial published following adverse events of gene therapy clinical trial

The Editor-in-Chief of Human Gene Therapy, the first journal devoted to the field of gene therapy, and one of the world's leading experts on gene therapy have co-authored a new editorial, Moving Forward After Two Deaths in a Gene Therapy Trial of Myotubular Myopathy, in response to the news of two deaths in a now-halted gene therapy clinical trial.

3 Jul 2020

Mutated European strain of coronavirus more contagious but less potent

The coronavirus pandemic is far from over as it actively spreads across the globe. The infection toll has reached a staggering 10.84 million people since it emerged in late December 2019 in Wuhan City, China. The virus that has left the city has now spread to 188 countries and territories and has mutated, becoming more infectious.

3 Jul 2020

Study may help develop better treatment strategies for cannabis dependence

Researchers at Center for BrainHealth, part of The University of Texas at Dallas, recently examined underlying brain networks in long-term cannabis users to identify patterns of brain connectivity when the users crave or have a desire to consume cannabis.

2 Jul 2020

Scientists test evolutionary fitness of older-mother offspring in various environments

The offspring of older mothers don't fare as well as those of younger mothers, in humans and many other species. They aren't as healthy, or they don't live as long, or they have fewer offspring themselves.

2 Jul 2020

Researchers find possible cause for SARS-CoV-2 reactive T cells in uninfected individuals

The current pandemic of COVID-19 is caused by the severe acute respiratory syndrome coronavirus (SARS-CoV) -2, leading to severe pneumonia, acute respiratory distress syndrome, and death in a sizable minority of cases. However, the most significant number are asymptomatic or have only mild infection from which they rapidly recover.

2 Jul 2020

More evidence on vitamin D deficiency and death rates from COVID-19

Physicians at the Complete Med Care clinic in Dallas, Texas, have conducted a study showing that the prevalence of severe vitamin D deficiency is strongly correlated with coronavirus disease 2019 (COVID-19) mortality rate in European countries.

2 Jul 2020

New formula more accurately compares the ages of humans and dogs

If there's one myth that has persisted through the years without much evidence, it's this: multiply your dog's age by seven to calculate how old they are in "human years." In other words, the old adage says, a four-year-old dog is similar in physiological age to a 28-year-old person.

2 Jul 2020

Researchers discover new candidate for raw material synthesis through gene transfer

Cyanobacteria hardly need any nutrients and use the energy of sunlight. Bathers are familiar with these microorganisms - often incorrectly called "blue-green algae" - as they often occur in waters.

2 Jul 2020