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A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

A recent study investigated the impact of a recombinant fragment of cellular glycoprotein Gal-3BP on IL-6 expression in acute COVID-19.

5 Apr 2022

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Researchers profiled cardiac tissue transcriptomes of COVID-19 patients.

5 Apr 2022

Cell Guidance Systems and Manchester BIOGEL collaborate to launch PODS-PeptiGels for 3D cell culture

Cell Guidance Systems Ltd today announced a collaboration to launch PODS®-PeptiGels®.

From Cell Guidance Systems 5 Apr 2022

Study provides new insights into cause of metastasis in prostate cancer

Prostate cancers remain localized in the majority of cases, giving affected individuals a good chance of survival.

4 Apr 2022

Powerhouse-pruning protein may also help make energy rapidly available for growing new blood vessels

A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it's time to make new blood vessels.

4 Apr 2022

The SAVE initiative to monitor the impact of SARS-CoV-2 variants

The SAVE initiative assesses the impact of SARS-CoV-2 variants on diagnostics, vaccines, and therapies, as well as communicating public health dangers.

4 Apr 2022

Key protein could be a novel target for treatment of patients with B cell signaling deficiencies

The rules to the kids' game "red light, green light" are easy to follow: red always means stop, and green always means go. But now, researchers from Japan have found that a key protein involved in B cell signaling acts as both a red light to signaling in healthy cells and a green light to signaling in immune-deficient cells.

4 Apr 2022

Study investigates targeted phenotyping of host proteins aiding drug repurposing in COVID-19

Researchers conducted selective phenotyping of coronavirus disease 2019 -relevant host proteins to facilitate target identification for drug repurposing.

4 Apr 2022

The effects of SARS-CoV-2 infection in different ancestry origins from the same region

Researchers examined whether varied allelic frequencies of the HLA gene in people of different ancestral origins were associated with increased susceptibility to SARS-CoV-2 infection and disease severity.

4 Apr 2022

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

In a recent study published in the journal PLOS Genetics, researchers explored severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) editing in host cells.

4 Apr 2022

mRNA-1273 and BNT162b2 COVID-19 vaccines induce slightly different immune responses

In a recent study published in the journal Science, researchers observed differential effector functions of antibodies elicited by Pfizer’s BNT162b2 and Moderna’s messenger ribonucleic acid (mRNA)-1273 coronavirus disease 2019 (COVID-19) vaccines.

4 Apr 2022

AI helps identify areas in need of emergency aid

In a recent study published in the journal Nature, researchers developed and evaluated an approach that used machine-learning algorithms to analyze mobile phone and satellite data to estimate poverty. They aimed to optimize the ‘Novissi’ flagship emergency social assistance program in Togo, West Africa, providing subsistence cash relief to those most affected by COVID-19.

4 Apr 2022

Smart toilets for passive surveillance of SARS-CoV-2

In a recent study published in Nature Digital Medicine, researchers highlighted a potential strategy for using a smart toilet platform, Coronavirus: Integrated Diagnostic (COV-ID), for passive monitoring of coronavirus disease 2019 (COVID-19).

3 Apr 2022

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Cardamonin - a natural compound found in the spice cardamom and other plants - could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells.

3 Apr 2022

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Scientists develop a formulation for the pulmonary administration of siRNA. The aim was to suppress the replication of SARS-CoV-2.

3 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

Eating prunes every day may reduce pro-inflammatory mediators in postmenopausal women

A study in postmenopausal people suggests eating nutrient-rich prunes every day may be beneficial to bone health, reducing inflammatory factors that contribute to osteoporosis.

2 Apr 2022

Analysis of antioxidants, stress markers in the blood could lead to new diagnostic tool for breast cancer

A new study that analyzes levels of antioxidants and stress markers in the blood could lead to a new diagnostic tool for breast cancer. The research will be presented this week in Philadelphia at the American Physiological Society's annual meeting at Experimental Biology 2022.

2 Apr 2022

Phenolic extract from wild blueberries may improve wound healing

Treating wounds with an extract taken from wild blueberries may improve healing, according to a new study.

2 Apr 2022

B Cell News and Research

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Cell Guidance Systems and Manchester BIOGEL collaborate to launch PODS-PeptiGels for 3D cell culture

Study provides new insights into cause of metastasis in prostate cancer

Powerhouse-pruning protein may also help make energy rapidly available for growing new blood vessels

The SAVE initiative to monitor the impact of SARS-CoV-2 variants

Key protein could be a novel target for treatment of patients with B cell signaling deficiencies

Study investigates targeted phenotyping of host proteins aiding drug repurposing in COVID-19

The effects of SARS-CoV-2 infection in different ancestry origins from the same region

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

mRNA-1273 and BNT162b2 COVID-19 vaccines induce slightly different immune responses

AI helps identify areas in need of emergency aid

Smart toilets for passive surveillance of SARS-CoV-2

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Eating prunes every day may reduce pro-inflammatory mediators in postmenopausal women

Analysis of antioxidants, stress markers in the blood could lead to new diagnostic tool for breast cancer

Phenolic extract from wild blueberries may improve wound healing

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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