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Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing's sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research shows that patients with poor outcomes have tumors with high levels of a protein known as GSTM4, which may suppress the effects of chemotherapy. The research is published online today in the journal Oncogene.

31 Aug 2009

Spinal implant developed by Sanfor Clinic neurosurgeon receives FDA market clearance

Sanford Health, a comprehensive health care provider in the Upper Midwest, announced today a spinal implant developed by Sanford Clinic Neurosurgeon, Wilson Asfora, MD, Sanford Clinic Neurosurgery & Spine, has received United States Food and Drug Administration (FDA) 510(k) market clearance as a lumbar intervertebral body fusion device.

31 Aug 2009

Study reveals that downregulation of IRF-8 gene causes gum diseases, arthritis and osteoporosis

Investigators at Hospital for Special Surgery, collaborating with researchers from other institutions, have contributed to the discovery that a gene called interferon regulator factor-8 (IRF-8) is involved in the development of diseases such as periodontitis (gum disease), rheumatoid arthritis and osteoporosis. The study, which will be published online August 30, ahead of print, in the journal Nature Medicine, could lead to new treatments in the future.

31 Aug 2009

FDA approves the usage of Valcyte for preventing CMV disease in pediatric patients

Roche announced today that the U.S. Food and Drug Administration (FDA) has approved Valcyte(R) (valganciclovir hydrochloride) for the prevention of cytomegalovirus (CMV) disease in pediatric kidney and heart transplant patients (4 months to 16 years of age) at high risk of developing CMV disease.

31 Aug 2009

Genzyme’s supplemental NDA for treating adult AML with Clolar to be discussed by the FDA

Genzyme Corporation (Nasdaq: GENZ) announced today that its supplemental New Drug Application for Clolar® (clofarabine) will be discussed Tuesday, September 1 at a public meeting of the FDA’s Oncologic Drugs Advisory Committee in Silver Spring, Maryland. The panel is expected to consider the clinical trial results Genzyme submitted to support the approval and labeling of Clolar to treat older adult patients with acute myeloid leukemia (AML), the most common type of acute leukemia in adults.

29 Aug 2009

NYP/Weill Cornell research reveals that prolonged QRS duration indicates abnormal pumping of the heart

QRS duration (QRSd) is one of several measures of heart function recorded during a routine electrocardiogram (ECG). It is a composite of waves showing the length of time it takes for an electrical signal to get all the way through the pumping chambers of the heart. Prolonged QRSd is a sign of an abnormal electrical system of the heart and is often found when the heart isn't pumping efficiently.

28 Aug 2009

Study on basic mechanisms that control fertility in worms may help to know how some woman regain their fertility after cancer treatment

Scientific dogma has long asserted that females are born with their entire lifetime's supply of eggs, and once they're gone, they're gone. New findings by researchers at Fred Hutchinson Cancer Research Center, published online Aug. 27 in Science, suggest that in nematode worms, at least, this does not hold true.

28 Aug 2009

Sagent Pharmaceuticals adds fluconazole injection to its line of premixed bags

Sagent Pharmaceuticals, Inc., a privately held specialty pharmaceutical company, today announced that it has launched fluconazole injection in premix bags. IMS Health estimates that 2008 U.S. sales of fluconazole injection approximated $18 million. Sagent will begin marketing and shipping fluconazole bags immediately.

28 Aug 2009

FDA provides marketing clearance for the spinal implant developed by Sanford Health

28 Aug 2009

Medical journal article highlights the challenges faced by healthcare providers for treating patients with non-healing wounds

Cardium Therapeutics today reported that a recent medical journal article highlights the challenges facing healthcare providers with respect to finding optimal treatments for patients with non-healing wounds.

28 Aug 2009

Cardea and Optasia to collaborate on configuring their Vertebral Fracture Assessment software tools

Cardea Technology, Inc. and Optasia Medical Ltd., announce plans to collaborate and configure their software tools for Vertebral Fracture Assessment, a method for evaluating vertebral fractures from images on bone densitometers, to exchange information and create reports for the management of osteoporosis.

28 Aug 2009

Arno Therapeutics to commence Phase 1 clinical study of AR-12 in adult patients with lymphoma

Arno Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on oncology therapeutics, today announced the dosing of the first patient in a Phase I clinical study of AR-12 (formerly OSU-03012) in adult patients with advanced or recurrent solid tumors or lymphoma.

28 Aug 2009

European Medicines Agency validates Schering-Plough's MAA for nomegestrol acetate/17 beta-estradiol

Schering-Plough Corporation, (NYSE: SGP), today announced that the European Medicines Agency (EMEA) has validated (accepted for review) the company's Marketing Authorization Application (MAA) for a fixed-dose combination of mometasone furoate and formoterol fumarate for the maintenance treatment of asthma in patients 12 years of age and older.

27 Aug 2009

Inventor of the SPIDER Limb Positioner wins a $10,000 Manning Innovation Award

Calgary biomed engineer Brent King is to win a $10,000 Manning Innovation Award for inventing a unique device to accurately and securely position a surgical patient's limb.

27 Aug 2009

Study reveals effectiveness of BioElectronics' ActiPatch therapy device for treating heel and foot pain

BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, today announced the completion of an important clinical study on heel and foot pain, which was led by David Genecov, M.D. FACS FAAP.

27 Aug 2009

Muscular thighs protect women from developing symptomatic knee osteoarthritis

new study by researchers at the University of Iowa Hospitals and Clinics found that thigh muscle strength does not predict the occurrence of knee osteoarthritis (OA) uncovered in x-rays, but does predict incidence of painful or stiff knee OA. Women with the strongest quadriceps muscles appeared to be protected against the development of knee OA symptoms. Details of this study appear in the September issue of Arthritis Care & Research.

27 Aug 2009

AOFAS announces results of clinical trials with the STAR ankle replacement device

Charles L. Saltzman, MD, newly-elected president of the American Orthopaedic Foot & Ankle Society (AOFAS), presented the results of a groundbreaking study at the recent AOFAS 2009 Annual Summer Meeting in Vancouver, British Columbia, Canada.

26 Aug 2009

Cardium announced that patients enrolled for MATRIX clinical trail have completed their evaluation period

Cardium Therapeutics (NYSE Amex: CXM) today announced that all patients enrolled in the Company's MATRIX clinical study have now completed their initial 12-week evaluation period and that it plans to provide detailed safety and efficacy data in late September 2009.

26 Aug 2009

Mutations of gene regulators can result in growth disorders

A specific gene is particularly frequently involved in the development of short stature. Researchers in Heidelberg have now discovered that sequences of genetic material on the X and Y chromosome that regulate this gene are also crucial for growth in children.

26 Aug 2009

$Rates of hip fracture decline in Canada$

Rates of hip fracture decline in Canada

Standardized rates of hip fracture have steadily declined in Canada since 1985, with a more rapid decline between 1996 and 2005 and a more marked decrease among individuals age 55 to 64 years, according to a report in the August 26 issue of JAMA.

25 Aug 2009

Bone News and Research

Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

Spinal implant developed by Sanfor Clinic neurosurgeon receives FDA market clearance

Study reveals that downregulation of IRF-8 gene causes gum diseases, arthritis and osteoporosis

FDA approves the usage of Valcyte for preventing CMV disease in pediatric patients

Genzyme’s supplemental NDA for treating adult AML with Clolar to be discussed by the FDA

NYP/Weill Cornell research reveals that prolonged QRS duration indicates abnormal pumping of the heart

Study on basic mechanisms that control fertility in worms may help to know how some woman regain their fertility after cancer treatment

Sagent Pharmaceuticals adds fluconazole injection to its line of premixed bags

FDA provides marketing clearance for the spinal implant developed by Sanford Health

Medical journal article highlights the challenges faced by healthcare providers for treating patients with non-healing wounds

Cardea and Optasia to collaborate on configuring their Vertebral Fracture Assessment software tools

Arno Therapeutics to commence Phase 1 clinical study of AR-12 in adult patients with lymphoma

European Medicines Agency validates Schering-Plough's MAA for nomegestrol acetate/17 beta-estradiol

Inventor of the SPIDER Limb Positioner wins a $10,000 Manning Innovation Award

Study reveals effectiveness of BioElectronics' ActiPatch therapy device for treating heel and foot pain

Muscular thighs protect women from developing symptomatic knee osteoarthritis

AOFAS announces results of clinical trials with the STAR ankle replacement device

Cardium announced that patients enrolled for MATRIX clinical trail have completed their evaluation period

Mutations of gene regulators can result in growth disorders

Rates of hip fracture decline in Canada

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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