Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

Study shows risk of MIS-C post mRNA vaccination against COVID-19 in children with autoimmune complications

Researchers discuss two cases of MIS-V after the patients had received the SARS-CoV-2 vaccine from Pfizer/BioNTech (BNT162b2).

23 Nov 2021

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Scientists investigate the neuroinvasive potential of SARS-CoV-2 and the role of tunneling nanotubes (TNTs) in spreading the infection to neighboring cells.

23 Nov 2021

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

A new combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson's disease-afflicted brain cells, according to a Northwestern Medicine study published in Neuron.

23 Nov 2021

Novel protein regulator of tumor angiogenesis may be a therapeutic target for difficult-to-treat cancers

A novel protein regulator of tumor angiogenesis, TMEM230, was recently characterized by researchers to have a role in tumor development and vascularization, with potential as a target for anti-tumor therapy in difficult-to-treat cancers such as glioblastoma.

23 Nov 2021

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Scientists utilize N. benthamiana for producing the N-protein and an antigenic cocktail containing the N-protein and SARS-CoV-2 S RBD.

23 Nov 2021

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Scientists generate a VLP type NP platform made of recombinant viral antigens conjugated with TMV virions.

23 Nov 2021

An increase in the half-life of remdesivir for COVID-19 treatment

In this study, researchers analyzed several drug candidates to investigate their efficacy against a broad spectrum of coronaviruses in cell culture studies.

23 Nov 2021

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

New research suggests that SARS-CoV-2 infection can directly target and cause cellular damage to the adrenal glands.

23 Nov 2021

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

In a study recently published on the bioRxiv preprint server, researchers attempted to further increase the scope of previous studies in examining SARS-CoV-2 infection of human CNS resident cells.

22 Nov 2021

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

In a study recently published on the bioRxiv* preprint server, researchers investigated the IFITM2 dependency of SARS-CoV-2 VOCs, including the delta variant for efficient infection.

22 Nov 2021

Donor cells with clonal hematopoiesis may improve bone marrow transplant outcomes

Clonal hematopoiesis, a condition in which mutations associated with blood cancers are found in the blood of healthy people, is common with aging.

22 Nov 2021

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.

22 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Other molecules may have greater potential as cancer therapies than gold complex auranofin

The gold complex auranofin has traditionally been used for treating rheumatism but is also being evaluated as a treatment for certain forms of cancer.

22 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

New score developed to predict outcome in liver cancer patients receiving immunotherapy

There are still no established biomarkers to predict the success of immunotherapy in patients with liver cancer.

22 Nov 2021

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

Study shows porcine deltacoronavirus (PDCoV) is capable of zoonotic transfer

A team of researchers describes the presence of PDCoV strains in plasma samples of three Haitian children with acute undifferentiated febrile illness.

22 Nov 2021

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Turkish researchers discuss their rapid electrochemical biosensing platform to detect the SARS-CoV-2 spike antibody.

22 Nov 2021

Protein News and Research

Further Reading

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

Study shows risk of MIS-C post mRNA vaccination against COVID-19 in children with autoimmune complications

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

Novel protein regulator of tumor angiogenesis may be a therapeutic target for difficult-to-treat cancers

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

An increase in the half-life of remdesivir for COVID-19 treatment

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

Donor cells with clonal hematopoiesis may improve bone marrow transplant outcomes

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Other molecules may have greater potential as cancer therapies than gold complex auranofin

Paper-based innovations for COVID-19 diagnosis

New score developed to predict outcome in liver cancer patients receiving immunotherapy

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

Study shows porcine deltacoronavirus (PDCoV) is capable of zoonotic transfer

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

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