Infectious Diseases News and Research

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Technique called real-time polymerase chain reaction speeds up detecting, treating wound bacteria

Using DNA detection methods though a technique called real-time polymerase chain reaction, the physician-researcher from the West Los Angeles Veterans Administration Medical Center can drastically cut the time it takes for lab personnel to figure out just what bacteria they're dealing with.

1 Jun 2006

$21 billion for HIV/AIDS, is it paying off?

This year, the U.S. federal government will spend $21 billion for HIV/AIDS research, treatment, prevention, and related activities. Is this enormous expenditure paying off?

1 Jun 2006

Organ-recipients' deaths prompt call for suppliers of pet rodents to screen for lymphocytic choriomeningitis virus

A case involving seven transplant recipients killed by a rodent-borne virus that they apparently acquired from donated and infected human organs has prompted a recommendation that regulatory authorities require suppliers of pet rodents to screen their colonies for the virus.

1 Jun 2006

Promising new vaccine delivery approach

The field of vaccine development is getting a boost from new research that has identified a promising vaccine delivery approach, which in animal studies produced long-term immune protection after just one immunization.

31 May 2006

Higher dose of flu vaccine improves immune response in the elderly

There may be a simple way to provide elderly Americans with extra protection against the annual flu virus: give them a higher dose of seasonal flu vaccine.

23 May 2006

Two more deaths from bird flu as Indonesia tries to track down souce of 'cluster' deaths

While Health officials in Indonesia are still trying to track down the source of infection in a cluster of six deaths in one family from H5N1 bird flu, tests show that two more people have also died of the same disease.

23 May 2006

Malaria - the left hand doesn't know what the right hand is doing!

The World Health Organisation (WHO) is quite rightly patting itself on the back because it has persuaded as many as 13 drug companies to abandon the marketing and promotion of monotherapy in the treatment of Malaria.

16 May 2006

Full year of treatment with pyrimethamine and sulfadiazine helps infants and children with toxoplasmosis

The first long-term study shows that treatment with pyrimethamine and sulfadiazine (two anti-parasitic drugs) during the first year of life leads to a lasting reduction in brain and eye damage for children with congenital toxoplasmosis.

16 May 2006

Transitions to injecting drug use among noninjecting heroin users

In a study reported in the current issue of the Journal of Acquired Immune Deficiency Syndromes, scientists from the National Development and Research Institutes, Inc. (NDRI) report on a study of street-recruited heroin users in New York City, who were not injecting, to determine the incidence and predictors of making a transition to injecting.

11 May 2006

Abortion pill in trouble again

Clostridium sordellii is a rare germ that has killed four women who took the abortion pill RU-486 and has also been implicated in the deaths of at least 11 other women following childbirth or miscarriage.

11 May 2006

Study reveals structure of E. coli multidrug transporter protein

This new study could potentially help researchers find new ways to avoid the problem of multidrug resistance and enhance the potency of existing drug compounds.

9 May 2006

Renewed interest in studying influenza A viruses

The emergence of the avian influenza virus H5N1 that is currently devastating chicken flocks in many countries and threatening to unleash a worldwide epidemic among humans has triggered a renewed interest among scientists in studying influenza A viruses, according to investigators at St. Jude Children's Research Hospital.

9 May 2006

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells

A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. RNA interference has recently emerged as an important tool in studying how genes function in normal biological processes and in disease.

9 May 2006

Chancroid vaccine may help control HIV in Africa

HIV plagues more than 25 million people in sub-Saharan Africa, according to the World Health Organization, and efforts to develop a vaccine against the virus have achieved limited success.

8 May 2006

Trial of hepatitis C vaccine underway

Human clinical trials involving investigational vaccines to prevent Hepatitis C are rare. In the fall of 2003 there was a first-ever study at Saint Louis University Center for Vaccine Development, and an earlier small study at Johns Hopkins School of Medicine.

8 May 2006

Saint Louis University hunt for a Hepatitis C vaccine

3 May 2006

New vaccine against lethal avian influenza virus shows promise

A commercially developed vaccine has successfully protected mice and ferrets against a highly lethal avian influenza virus, according to the investigator who led the study at St. Jude Children's Research Hospital.

3 May 2006

Epstein-Barr virus may trigger multiple sclerosis

Researchers have found that patients with multiple sclerosis (MS) carry a population of immune cells that overreact to Epstein-Barr virus.

3 May 2006

Short-course postexposure antibiotic prophylaxis combined with vaccination protects against experimental inhalational anthrax

Anthrax vaccine administered in combination with a short course of antibiotics completely protected nonhuman primates from inhalational anthrax, the most lethal form of the disease, according to scientists at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).

3 May 2006

Study investigates early biology of HIV infection

In July 2005, the race to find a vaccine that would stem the worldwide rate of 13,000 new cases of HIV infection each day moved from competition among research institutions to a strategy of cooperation.

2 May 2006