Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Study analyzes association between obesity and endothelial dysfunction in COVID-19 patients

In COVID-19 patients, obesity is the factor most associated with the development of endothelial dysfunction, a condition in which the blood vessels become unable to contract and relax adequately, increasing the risk of events such as heart attacks, thrombosis (blood clotting), and stroke.

15 Nov 2021

Researchers develop a highly efficient method to generate immune cells for cancer therapies

A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens - small fragments of randomly mutated proteins that are typically unique to a patient's cancer - and destroy the tumors that express them.

15 Nov 2021

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

A recent study investigates histone mimicry as a mechanism by SARS-CoV-2 for disrupting epigenetic regulation to evade host cell responses to infection.

15 Nov 2021

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

A new study investigates serum from COVID-19 convalescents and uninfected individuals to determine the molecular mechanisms of host responses.

15 Nov 2021

Study offers new insight into the role of tau proteins in ALS pathogenesis

A team led by investigators at Massachusetts General Hospital has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated levels of tau and phosphorylated tau protein in the motor cortex region of the brain.

15 Nov 2021

Scientists develop a promising new approach to potentially treat Alzheimer's disease

A promising new approach to potentially treat Alzheimer's disease – and also vaccinate against it – has been developed by a team of UK and German scientists.

15 Nov 2021

Oral PCSK9-inhibitor highly effective at reducing high levels of LDL cholesterol, studies show

Results from two early clinical studies show the first version of an oral PCSK9-inhibitor cholesterol-lowering medicine was well tolerated and highly effective at reducing high levels of LDL cholesterol, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Stem cell treatment reduced deaths related to cardiovascular issues, not hospitalization

Stem cell therapy helped to reduce the number of heart attacks, strokes and death among people with chronic, high-risk, NYHA class II or III heart failure with reduced ejection fraction (HFrEF), especially among those who have higher levels of inflammation, yet hospitalization was not reduced, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Lamin C important for keeping cell’s genetic material organized, research shows

In a study with lab-grown mouse cells, Johns Hopkins Medicine researchers say they have found that a protein that helps form a structural network under the surface of the cell's "command center" — its nucleus — is key to ensuring that DNA inside it remains orderly.

15 Nov 2021

Researchers discover new gene critical for daily behavioral rhythms

Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type. When a clock goes awry, sleep disruption or a variety of diseases can result.

15 Nov 2021

Anti-platelet drug class fails to extend survival in moderately ill COVID-19 patients

A drug class that blocks the activity of blood platelets and prevents clotting—P2Y12 inhibitors—failed to extend survival or lessen disease severity in patients with COVID-19 who were hospitalized but had a relatively moderate case, a new study finds.

15 Nov 2021

Research expands the general understanding of transcription process in bacteria

Bacteria need to constantly adapt to compete against other species for nutrient sources and to survive against threats such as antibiotics and toxins.

15 Nov 2021

New therapy targets rodents' cells rather than bacterial cells in treating pneumonia

Researchers at the National Institutes of Health have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia in rodents.

15 Nov 2021

Could drugs derived from microalgae be effective against COVID-19?

Researchers discuss the ability of some microalgae metabolites to prevent cytokine storm syndrome during COVID-19.

15 Nov 2021

Updated mapping of the human genetic architecture of COVID-19

In the present study, researchers presented extensive meta-analysis and added ten new genome-wide significant loci.

15 Nov 2021

Vaccination protects against COVID-19 related hospitalization in patients with and without comorbidity

Researchers from University Medical Centre Utrecht have been investigating the efficiency of vaccines against the alpha variant in the Netherlands.

15 Nov 2021

Detection of a coronavirus similar to SARS-CoV-2 in Cambodian bats

Now, a new study published in the journal Nature Communications reports the identification of SARS-CoV-2 related coronaviruses in two horseshoe bats sampled in Cambodia in 2010.

15 Nov 2021

The case for vaccinating children under 12 against COVID-19

Researchers assess the need for coronavirus disease 2019 (COVID-19) vaccination in children who are 12 years of age or younger.

14 Nov 2021

Can COVID-19 vaccination lead to neurological complications?

A new review article discusses the neurological side effects due to SARS-CoV-2 vaccination.

14 Nov 2021

Increased risk of breakthrough SARS-CoV-2 infection with ChAdOx1 compared to BNT162b2 vaccine

Researchers study individuals recruited in the ‘Virus Watch’ community cohort who had received their second dose of either ChAdOx1 or BNT162b2 vaccine.

14 Nov 2021

Protein News and Research

Further Reading

Study analyzes association between obesity and endothelial dysfunction in COVID-19 patients

Researchers develop a highly efficient method to generate immune cells for cancer therapies

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

Study offers new insight into the role of tau proteins in ALS pathogenesis

Scientists develop a promising new approach to potentially treat Alzheimer's disease

Oral PCSK9-inhibitor highly effective at reducing high levels of LDL cholesterol, studies show

Stem cell treatment reduced deaths related to cardiovascular issues, not hospitalization

Lamin C important for keeping cell’s genetic material organized, research shows

Researchers discover new gene critical for daily behavioral rhythms

Anti-platelet drug class fails to extend survival in moderately ill COVID-19 patients

Research expands the general understanding of transcription process in bacteria

New therapy targets rodents' cells rather than bacterial cells in treating pneumonia

Could drugs derived from microalgae be effective against COVID-19?

Updated mapping of the human genetic architecture of COVID-19

Vaccination protects against COVID-19 related hospitalization in patients with and without comorbidity

Detection of a coronavirus similar to SARS-CoV-2 in Cambodian bats

The case for vaccinating children under 12 against COVID-19

Can COVID-19 vaccination lead to neurological complications?

Increased risk of breakthrough SARS-CoV-2 infection with ChAdOx1 compared to BNT162b2 vaccine

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