Biochemistry News and Research

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Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium.

29 Nov 2021

Research reveals how disordered protein interaction orchestrates gene expression

A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered a new piece of the puzzle of how gene expression is orchestrated.

25 Nov 2021

New technique may be a significant leap forward in the understanding of human cells

Most human diseases can be traced to malfunctioning parts of a cell — a tumor is able to grow because a gene wasn't accurately translated into a particular protein or a metabolic disease arises because mitochondria aren't firing properly, for example. But to understand what parts of a cell can go wrong in a disease, scientists first need to have a complete list of parts.

24 Nov 2021

Novel protein regulator of tumor angiogenesis may be a therapeutic target for difficult-to-treat cancers

A novel protein regulator of tumor angiogenesis, TMEM230, was recently characterized by researchers to have a role in tumor development and vascularization, with potential as a target for anti-tumor therapy in difficult-to-treat cancers such as glioblastoma.

23 Nov 2021

Other molecules may have greater potential as cancer therapies than gold complex auranofin

The gold complex auranofin has traditionally been used for treating rheumatism but is also being evaluated as a treatment for certain forms of cancer.

22 Nov 2021

Study underscores why COVID-19 vaccine boosters are important for all adults

As widely-anticipated decisions about COVID-19 vaccine boosters roll out from U.S. agencies today, insights from an independent study underscore why boosters are important for all adults.

21 Nov 2021

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Scientists recently gained insights into how vitamin D functions to reduce inflammation caused by immune cells that might be relevant to the responses during severe COVID-19. In a study jointly published by Purdue University and the National Institutes of Health, scientists do just that.

18 Nov 2021

Study identifies possible link between psychological stress and Crohn's disease flare-ups

A possible link between psychological stress and Crohn's disease flare-ups has been identified by a McMaster University-led study.

18 Nov 2021

Scientists use advanced microscopes to delve deeper into protein degradation process

Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.

17 Nov 2021

Study reveals complex interplay between diet, gut microbiota, and immune function

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

17 Nov 2021

Scientists predict structures of eukaryotic protein complexes using AI

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

ALS also causes retinal alterations, study reveals

Amyotrophic lateral sclerosis (ALS), characterized by harm to brain neurons and to the spinal cord, also affects the tissue of the retina, according to a study headed up by Universidad Complutense de Madrid.

16 Nov 2021

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Researchers discuss a highly sensitive, specific, and rapid SARS-CoV-2 detection platform by coupling the RT-LAMP with glass nanopore sensors.

11 Nov 2021

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

10 Nov 2021

Milestone study uncovers genetic risk factors for spine osteoarthritis

Scientists from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), contributing as part of the 'Genetics of Osteoarthritis (GO)' consortium to the world's largest study of over 800,000 individuals, have identified genetic risk factors - variants associated with SOX5 and CHST3 genes, key regulators of the development of the intervertebral discs, to be implicated in spine osteoarthritis (OA).

8 Nov 2021

Biochemistry News and Research

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Clinical drug research for the treatment of CNS and neurological disorders

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Research reveals how disordered protein interaction orchestrates gene expression

New technique may be a significant leap forward in the understanding of human cells

Novel protein regulator of tumor angiogenesis may be a therapeutic target for difficult-to-treat cancers

Other molecules may have greater potential as cancer therapies than gold complex auranofin

Study underscores why COVID-19 vaccine boosters are important for all adults

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Study identifies possible link between psychological stress and Crohn's disease flare-ups

Scientists use advanced microscopes to delve deeper into protein degradation process

Study reveals complex interplay between diet, gut microbiota, and immune function

Scientists predict structures of eukaryotic protein complexes using AI

ALS also causes retinal alterations, study reveals

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Milestone study uncovers genetic risk factors for spine osteoarthritis

Scientists create a rapid diagnostic technology to detect SARS-CoV-2

Brooklyn College announces the launch of BCCC-CURE to enhance the lives of cancer patients

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

Binding kinetics in drug discovery eBook eBook

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