Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Study shows potential of web-based intervention to achieve weight loss in patients with NAFLD

Patients with non-alcoholic fatty liver disease who participated in a web-based lifestyle modification intervention achieved similar levels of weight loss and more rapid normalization of their liver enzymes than patients who participated in an intensive, group-based program.

13 Apr 2018

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Kandice Fogle, 43, had just moved to Houston when she began experiencing pain in her back and groin. After undergoing a CT scan, doctors found a large mass in her liver. A biopsy confirmed that she had intrahepatic cholangiocarcinoma, more commonly known as bile duct cancer.

11 Apr 2018

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

The microbiome is the collection of microorganisms that colonize the human body. Dr. Jasmohan Bajaj discusses the relationship between the microorganisms in the gut and cirrhosis, and how microbiome analysis can be used to predict the risk of cirrhosis-associated hospitalizations.

7 Apr 2018

Research links DNA variants to increased risk of IBS in women

New research coordinated by Karolinska Institutet in Sweden links certain DNA variants to increased risk of irritable bowel syndrome in women. The findings, published in the scientific journal Gastroenterology, might help explain why IBS is more common in women than in men.

5 Apr 2018

Expert group presents framework to address physician burnout

Physician burnout continues to be a pervasive issue, with more than 50 percent of doctors reporting problems such as dissatisfaction, high rates of depression, and increased suicide risk.

29 Mar 2018

Researchers develop wearable system to monitor electrical activity in the stomach over 24 hours

A team of researchers has developed a wearable, non-invasive system to monitor electrical activity in the stomach over 24 hours--essentially an electrocardiogram but for the gastro-intestinal (GI) tract.

22 Mar 2018

Artificial sweetener sucralose worsens gut inflammation in mice with Crohn's disease

In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six-week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's-like disease, but had no substantive effect on those without the condition.

15 Mar 2018

Eight-week hepatitis C treatment regimen may be just as effective as 12 weeks in black patients

A study by the Harvard Pilgrim Health Care Institute found that contrary to current hepatitis C treatment guidelines, an eight-week treatment regimen may be just as effective as 12 weeks in black patients.

15 Mar 2018

Routine screenings and early detection can help protect from colorectal cancer

Having a colonoscopy to screen for colorectal cancer is not on anyone's list of favorite activities. However, with colorectal cancer ranking as the second leading cause of cancer death in the United States, undergoing the outpatient procedure as per the Centers for Disease Control's (CDC) guidelines may be one of the smartest things you can do for your overall health.

9 Mar 2018

Gastrointestinal hormone offers possible new treatment for NAFLD and NASH patients

Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

9 Mar 2018

Researchers show complex link between physical, behavioral characteristics and brain health

Mount Sinai researchers have shown, for the first time, the complex web of links between physical and behavioral characteristics, like age, body mass index (BMI), and substance use, and specific patterns of brain structure and function in patients with psychosis.

7 Mar 2018

People 85 and older with high cholesterol have reduced risk for cognitive decline, study reports

People aged 85 and older whose total cholesterol had increased from their levels at midlife had a reduced risk for marked cognitive decline, compared with those a decade younger whose cholesterol was similarly elevated, Mount Sinai researchers report in a new study.

6 Mar 2018

MSD and Ferring Pharmaceuticals Complete Largest Ever Clinical Trial in Postpartum Haemorrhage

Today, Ferring Pharmaceuticals and MSD, via its MSD for Mothers initiative, announced the completion of CHAMPION (Carbetocin Haemorrhage Prevention), a global clinical trial conducted by the Human Reproduction Program (HRP) at the World Health Organization (WHO).

22 Feb 2018

Cancer initiation found to be similar across organs

Recent research at Washington University School of Medicine in St. Louis demonstrated that mature cells in the stomach sometimes revert back to behaving like rapidly dividing stem cells.

21 Feb 2018

Study: Diagnosis of celiac disease takes 3.5 years for patients who do not report GI symptoms

It takes an average of 3.5 years to diagnose celiac disease in patients who do not report gastrointestinal symptoms, a Loyola Medicine study has found.

19 Feb 2018

University Hospital of Santiago de Compostela participates in large pancreatic cancer study

International validation through collaboration with leading cancer centers in Europe and US is a key part of Immunovia’s development and commercialization strategy for its portfolio of IMMray tests.

19 Feb 2018

New guidelines offer recommendations for assessment, management of immunotherapy side effects

Immunotherapy with immune checkpoint inhibitors is the first of a new generation of immunotherapy treatments, revolutionizing treatment for many different types of cancer. By unleashing the body's immune system to attack cancer, these treatments can send even the most hard-to-treat cancers into lasting remission.

15 Feb 2018

Testing for alpha fetoprotein may improve early liver cancer detection, finds study

A new study found that ultrasound imaging in combination with a blood test for alpha fetoprotein improved the detection of early-stage liver cancer by 40%.

12 Feb 2018

Gastroenterology News and Research

Further Reading

Study shows potential of web-based intervention to achieve weight loss in patients with NAFLD

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

Research links DNA variants to increased risk of IBS in women

Expert group presents framework to address physician burnout

Researchers develop wearable system to monitor electrical activity in the stomach over 24 hours

Artificial sweetener sucralose worsens gut inflammation in mice with Crohn's disease

Eight-week hepatitis C treatment regimen may be just as effective as 12 weeks in black patients

Routine screenings and early detection can help protect from colorectal cancer

Gastrointestinal hormone offers possible new treatment for NAFLD and NASH patients

Researchers show complex link between physical, behavioral characteristics and brain health

People 85 and older with high cholesterol have reduced risk for cognitive decline, study reports

MSD and Ferring Pharmaceuticals Complete Largest Ever Clinical Trial in Postpartum Haemorrhage

Cancer initiation found to be similar across organs

Study: Diagnosis of celiac disease takes 3.5 years for patients who do not report GI symptoms

University Hospital of Santiago de Compostela participates in large pancreatic cancer study

New guidelines offer recommendations for assessment, management of immunotherapy side effects

Testing for alpha fetoprotein may improve early liver cancer detection, finds study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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