Lung Disease News and Research

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Statin medications can cause necrotizing myopathy in some patients

Statin medications, such as Crestor, Lipitor, and other lipid-lowering medications, have been prescribed increasingly in recent years to reduce cardiovascular disease and mortality in high risk individuals.

6 Jun 2017

Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer

Novartis today announced it has entered into a clinical research collaboration in which Bristol-Myers Squibb will investigate the safety, tolerability, and efficacy of Mekinist (trametinib) in combination with Opdivo (nivolumab) and Opdivo + Yervoy (ipilimumab) regimen as a potential treatment option for metastatic colorectal cancer in patients with microsatellite stable tumors where the tumors are proficient in mismatch repair (MSS mCRC pMMR).

5 Jun 2017

FIRS releases new report that outlines global burden of respiratory disease

The Forum of International Respiratory Societies, an organization comprised of the world’s leading international respiratory societies working together to improve lung health globally, today released “The Global Impact of Respiratory Disease.” The report lays out the tremendous impact that respiratory disease has on world health.

26 May 2017

ERT’s Centralized LCI Services improve data quality to measure disease progression in respiratory clinical trials

ERT, a global data and technology company that minimizes uncertainty and risk in clinical trials, today introduced an advanced respiratory clinical trial solution to centrally capture, measure and analyze Lung Clearance Index data, in near real-time, to assess lung performance with more precision than traditional spirometry measures.

26 May 2017

CT-measured vascular pruning linked to mortality risk in smokers without COPD

In a new study, CT-measured vascular pruning – the diminution of distal pulmonary blood vessels (vessels on the outer edges of the lungs) – was associated with increased risk of death in smokers without chronic obstructive pulmonary disease.

23 May 2017

Exposure to high prenatal stress and air pollution linked to increased risk for childhood asthma

A new study has found that children, especially boys, whose mothers were exposed to higher levels of outdoor particulate air pollution at the same time that they were very stressed were most likely to develop asthma by age six.

22 May 2017

Biomarker may predict death or poor pulmonary outcomes in extremely preterm infants

Tests of cells collected from the umbilical cord blood vessel walls at birth can predict death or poor pulmonary outcomes in extremely preterm infants, say researchers at the University of Alabama at Birmingham.

22 May 2017

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Two T cell biomarkers appear to predict the survival trajectory of patients with idiopathic pulmonary fibrosis (IPF), a lung disease that has a varied, but ultimately devastating, impact on patients, according to new research presented at the ATS 2017 International Conference.

22 May 2017

Exposure to air pollution may disturb good night's sleep

High levels of air pollution over time may get in the way of a good night's sleep, according to new research presented at the ATS 2017 International Conference.

22 May 2017

Clinical trial offers new hope for patients suffering from severe lung disease

Patients suffering from severe lung disease could see their lives transformed thanks to a 'game-changing' clinical trial carried out by UK experts and led by the team from the Lane Fox Respiratory Service based at Guy's and St Thomas' in London.

22 May 2017

Analysis explores impact of valve design on post-TAVR outcomes

For patients who undergo transcatheter aortic valve replacement (TAVR), their risk factors, not the type of valve used, determined their 30-day post-TAVR outcomes.

15 May 2017

CUMC researchers create new organoids that mimic features of full-sized lung

New lung "organoids"-tiny 3-D structures that mimic features of a full-sized lung- have been created from human pluripotent stem cells by researchers at Columbia University Medical Center. The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.

11 May 2017

Anti-smoking drug safe for COPD patients, research suggests

Medication that helps smokers to quit is safe for use by people with chronic lung conditions, research suggests.

10 May 2017

Scientists grow and purify earliest lung progenitors from human stem cells

Human lungs, like all organs, begin their existence as clumps of undifferentiated stem cells. But in a matter of months, the cells get organized. They gather together, branch and bud, some forming airways and others alveoli, the delicate sacs where our bodies exchange oxygen for carbon dioxide.

3 May 2017

New analysis shows high mortality and financial burden for pulmonary disease due to non-tuberculosis mycobacterium (NTM)

The first European study into the burden of non-tuberculosis mycobacterium pulmonary disease (NTM-PD), published today in the European Respiratory Journal, has revealed that both the 3-year all-cause mortality rate and financial burden for patients with the disease is almost four times higher than a matched control group.

2 May 2017

Takeda announces accelerated approval from FDA for new lung cancer treatment

Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that ALUNBRIG (brigatinib) has received Accelerated Approval from the U.S. Food and Drug Administration for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.

28 Apr 2017

Artificial womb could improve survival among premature babies

Researchers have designed a womb-like device that could allow premature babies to develop their lungs and organs in the critical few weeks that remain before they face the outside world.

26 Apr 2017

SLU researchers make advances in understanding plaque-causing protein in neurological disorders

In a recent paper published in the Journal of Biological Chemistry Yuna Ayala, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, and her research team made advances in understanding how a protein causes damaging plaques to build up in neurodegenerative illnesses like amyotrophic lateral sclerosis (ALS) and a form of dementia called frontotemporal lobar degeneration.

19 Apr 2017

Research project aims to develop new chip-sized optical microscope with high resolution capabilities

Creating a new type of chip-sized optical microscope with high resolution capabilities is the challenge of ChipScope, a European project led by the University of Barcelona which counts with the participation of SMEs, universities and research institutes from five European countries.

6 Apr 2017

Growth factors in cord blood may help identify preemies at risk for fatal lung disease

Findings published in the Journal of Pediatrics describe growth factors in cord blood that may identify premature infants at risk for bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) – an often fatal lung disease in which the vessels carrying blood from the heart to the lungs become narrowed and dysfunctional.

6 Apr 2017

Lung Disease News and Research

Statin medications can cause necrotizing myopathy in some patients

Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer

FIRS releases new report that outlines global burden of respiratory disease

ERT’s Centralized LCI Services improve data quality to measure disease progression in respiratory clinical trials

CT-measured vascular pruning linked to mortality risk in smokers without COPD

Exposure to high prenatal stress and air pollution linked to increased risk for childhood asthma

Biomarker may predict death or poor pulmonary outcomes in extremely preterm infants

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Exposure to air pollution may disturb good night's sleep

Clinical trial offers new hope for patients suffering from severe lung disease

Analysis explores impact of valve design on post-TAVR outcomes

CUMC researchers create new organoids that mimic features of full-sized lung

Anti-smoking drug safe for COPD patients, research suggests

Scientists grow and purify earliest lung progenitors from human stem cells

New analysis shows high mortality and financial burden for pulmonary disease due to non-tuberculosis mycobacterium (NTM)

Takeda announces accelerated approval from FDA for new lung cancer treatment

Artificial womb could improve survival among premature babies

SLU researchers make advances in understanding plaque-causing protein in neurological disorders

Research project aims to develop new chip-sized optical microscope with high resolution capabilities

Growth factors in cord blood may help identify preemies at risk for fatal lung disease

The ultimate guide to lung research tools and protocols eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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