Malignant News and Research

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Study shows how extracellular vesicles help melanoma cells to spread

A new study from Finland sheds fresh light on how melanoma cells interact with other cells via extracellular vesicles they secrete.

16 Jan 2020

UT Southwestern researchers explain racial disparities in heart failure risk

Researchers at UT Southwestern have uncovered evidence that the higher prevalence of "malignant" enlargement of the heart among blacks contributes to the higher incidence of heart failure in this population.

14 Jan 2020

Bath scientists identify promising route to develop new treatments for skin cancer

A promising route to develop new treatments for skin cancer has been identified by University of Bath scientists, who have found a molecule that suppresses melanoma tumor growth.

14 Jan 2020

Researchers analyze molecular characteristics of cerebrospinal fluid from LMM patients

Patients with advanced melanoma who develop metastases in the leptomeninges, the fluid filled membranes surrounding the brain and spinal cord, have an extremely dismal prognosis. Most patients only survive for 8 to 10 weeks after diagnosis.

11 Jan 2020

Asbestos exposure through cosmetic talc associated with mesothelioma

Thirty-three cases of the asbestos-related lung cancer mesothelioma draw attention to talcum powder as a non-occupational source of exposure to asbestos, according to a study in the January Journal of Occupational and Environmental Medicine.

9 Jan 2020

Administering enzalutamide results in significant increase in PSMA density on tumor surface

When a non-scientist tries to imagine a scientist, the image that often arises is one of a somewhat remote, rather idealistic genius sitting alone in their room or laboratory and somehow discovering the most amazing things without every having contact with the 'normal' world.

9 Jan 2020

CU Cancer Center named National Pancreas Foundation Center of Excellence

The most important factor predicting the survival of pancreatic cancer patients is whether the cancer can be surgically removed (whether the cancer is "resectable").

8 Jan 2020

Two-drug combination could be effective against malignant mesothelioma

Exposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggressive cancer that mostly affects the pleura - the tissue that lines the lungs - and the peritoneum - the tissue that lines the abdomen. This has been known for decades, yet the molecular characterisation of mesothelioma is barely known and treatment options are scarce.

8 Jan 2020

Study shows potential new approach to treating two common subtypes of lymphoma

A study at The University of Texas MD Anderson Cancer Center demonstrated a potential new approach to treating two of the most common subtypes of lymphoma through manipulation of molecular programs controlled by the cAMP-response element binding protein.

8 Jan 2020

Novel artificial intelligence algorithm helps detect brain tumor

Researchers have developed a new imaging technique and artificial intelligence algorithm that can help identify brain tumors.

7 Jan 2020

Novel imaging technique produces accurate, real-time intraoperative diagnosis of brain tumors

A novel method of combining advanced optical imaging with an artificial intelligence algorithm produces accurate, real-time intraoperative diagnosis of brain tumors, a new study finds.

6 Jan 2020

Bariatric surgery linked to reduction in malignant skin cancer risk

Bariatric surgery is associated with a distinct reduction in skin-cancer risk, a study shows. This finding can be described as a key piece of evidence that substantiates the connection between weight loss and malignant skin cancer.

2 Jan 2020

Study opens up new treatment possibilities for Wilms' tumor

As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched on, to what extent, and when.

18 Dec 2019

Yale researchers identify cellular chicanery that jumpstarts cancer

The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell behaviors, giving rise, scientists believe, to early stage cancer cells that eventually swamp normal cells and become deadly.

18 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Researchers identify molecular machinery that drives rapid polymerization of actin filaments

Many cells in our body constantly change their shape and move within our tissues. For example, wound healing and the immune system depend on migrating cells.

17 Dec 2019

New gene therapy has potential to reverse disease processes

Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.

17 Dec 2019

Evolutionarily novel genes found to be expressed in tumors

A team of scientists from Peter the Great St.Petersburg Polytechnic University (SPbPU) studied the evolutionary ages of human genes and identified a new class of them expressed in tumors -- tumor specifically expressed, evolutionarily novel (TSEEN) genes.

16 Dec 2019

Extensive tumor protein analysis reveals potential new players in cancer

Looking to gain a deeper understanding of cancer, a team led by researchers at Baylor College of Medicine conducted an extensive computational analysis of the similarities and differences in the entire set of proteins, called the proteome, of more than 500 cancers from five different tissue sites.

12 Dec 2019

UA physician-scientist to study how common stressors affect the aging process

The human body gets stressed every single day. Whether we contract a minor infection or even argue with a loved one, these small stressors impact our immune system.

10 Dec 2019