Malignant News and Research

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Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

The University of Barcelona and Hospital Clínic de Barcelona collaborate with Boehringer Ingelheim Inc. to improve the efficiency of nintedanib, an antiangiogenic and antifibrotic drug, for the treatment of lung cancer.

19 Nov 2019

New device separates malignant plasma cells from normal ones

Multiple myeloma is a type of blood cancer in which malignant plasma cells, a type of white blood cell, accumulate in the bone marrow.

19 Nov 2019

New microfluidics device detects malignant multiple myeloma cells in blood

Scientists have developed a microfluidics device that could be used for the detection or monitoring of multiple myeloma.

19 Nov 2019

New drug combo may improve pancreatic cancer therapy

A new study by scientists at Sanford Burnham Prebys Medical Discovery Institute have discovered a combination of two cancer-fighting drugs that successfully worked on pancreatic tumor in mice, shrinking them significantly, and paving the way for a speedy clinical trial designed to test their efficacy in humans.

18 Nov 2019

'Dysbiosis' promotes the onset of colorectal cancer

The gastroenterology team at Henri-Mondor AP-HP Hospital and University Paris-Est Créteil, led by Professor Iradj Sobhani, together with teams from Inserm and the Institut Pasteur Molecular Microbial Pathogenesis Unit (U1202), led by Professor Philippe Sansonetti - holder of the Microbiology and Infectious Diseases Chair at the Collège de France -, have demonstrated that an imbalance in the gut microbiota, also known as "dysbiosis", promotes the onset of colorectal cancer.

18 Nov 2019

Study on sea sponge opens up possibilities to create new antitumor drugs

Chemists from Far Eastern Federal University's School of Natural Sciences developed a new method to synthesize biologically active derivatives of fascaplysin -- cytotoxic pigment of a sea sponge. For the first time, they got a sufficient amount of 3-bromofascaplysin and 3,10-dibromofascaplysin, which were known before but were not available for study.

14 Nov 2019

Johns Hopkins launches new center for 'immunoengineering' research

If the saying that two heads are better than one is true, then joining two fields of science may be better than one to spur more advances in medicine.

13 Nov 2019

TSU researchers develop new approach to diagnose adenocarcinoma

Scientists have developed a new approach to the diagnosis of adenocarcinoma - a malignant tumor of the prostate gland. Artificial intelligence is used to determine oncopathology and determine the stage of the disease with this approach.

13 Nov 2019

Protein that drives pancreatic cancer growth could be new treatment target

A protein that drives growth of pancreatic cancer, and which could be a target for new treatments, has been identified by researchers at the Crick.

12 Nov 2019

Preclinical data on new drug combination to treat neuroblastoma published

Neuroblastoma is the most common cancer outside of the brain in infants and young children and often fails to respond to therapy. Though it can appear in several areas of the body, it commonly develops as a solid tumor most frequently found in or adjacent to the adrenal glands, which sit atop the kidneys.

10 Nov 2019

Study uncovers how cells 'forget their past' while developing into a specific cell

All cells in the body contain the same genetic material. The difference between cells therefore depends solely on which genes are expressed or ‘turned on’.

7 Nov 2019

New molecule can reduce aggressiveness of embryonal central nervous system tumors

In Brazil, scientists affiliated with the Human Genome and Stem Cell Research Center (HUG-CELL) at the University of São Paulo (USP) have identified a molecule capable of reducing the aggressiveness of embryonal central nervous system tumors.

7 Nov 2019

Oxygen-deprived tumor cells have survival advantage that promotes metastasis

Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream.

7 Nov 2019

CCNY researchers receive two U.S. patents for brain cancer-detecting innovation

Raising hopes of rapid and more specific brain cancer diagnoses, a new "Resonance Raman" technique developed by world-renowned physicist Robert R. Alfano and his IUSL research group at The City College of New York is the recipient of two U.S. patents.

6 Nov 2019

Study: Pleural effusions are linked with NSCLC and malignant mesothelioma

Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system.

6 Nov 2019

Affordable Care Act reduced rate of uninsured patients with head and neck cancers

The rate of uninsured patients with head and neck cancers was "significantly reduced" following the implementation of the federal Patient Protection and Affordable Care Act.

5 Nov 2019

Risk factors of malignant arrhythmias found in patients treated with therapeutic hyperthermia after cardiac arrest

Researchers showed that 20-50% of patients developed an irregular heartbeat that required defibrillation during the active cooling phase of therapeutic hypothermia following an out-of-hospital cardiac arrest.

5 Nov 2019

UK aims to lead with cutting-edge radiation therapy

The UK is all set to launch its run into the future as the undisputed leader in the field of personalized and effective radiation therapy. The proposal is undergirded by a whopping £56 million, which will be used to set up and fund advanced radiation therapy research by a new collaborative setup, Cancer Research UK RadNet, over five years. This is the largest sum ever invested by this organization into radiotherapy research.

4 Nov 2019

Some skin cancers originate in hair follicles, says new study

A new study published online in Nature Communicationson November 4, 2019, reports that some melanomas, which are among the deadliest skin cancers, originate in melanocyte stem cells that are located within the hair follicles.

4 Nov 2019

Study describes a molecular strategy that helps prevent development of tumors in mice

The body's process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process - except occasionally in the liver and adipose tissue - since most of the fatty acids we need for cell maintenance are obtained from the diet.

4 Nov 2019