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New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.

28 Oct 2022

Commensal gut microbes from IBD patients produce genotoxic metabolites

Functional screening of human gut microbiota reveals a family of small molecule genotoxins called indolimines in patients with inflammatory bowel disease (IBD), according to a new study.

27 Oct 2022

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University have taken a key step toward improving and lengthening the lives of cystic fibrosis patients, who experience chronically clogged airways and a dramatically shortened life expectancy.

27 Oct 2022

Cells in the brain's blood vessels necessary for fever reaction

Researchers at Linköping University have identified in mice the cells in the blood vessels of the brain that are necessary for a fever reaction.

26 Oct 2022

Study identifies an animal model that shares many similarities with progressive MS

A new study from UCLA researchers identified an animal model that could be used to study treatments for improving disabilities in multiple sclerosis patients.

25 Oct 2022

Researchers identify specific T cell required to bolster vaccine immunity against fungal pneumonia

Researchers at the University of Illinois College of Veterinary Medicine have demonstrated in a mouse model that a specific type of T cell, one of the body's potent immune defenses, produces cytokines that are necessary for the body to acquire immunity against fungal pathogens.

25 Oct 2022

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

UVA Health researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

17 Oct 2022

Structure of the irregular neuronal connection strengths contains a hidden order, study finds

In the brain, our perception arises from a complex interplay of neurons that are connected via synapses. But the number and strength of connections between certain types of neurons can vary.

14 Oct 2022

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

Researchers at Baylor College of Medicine and collaborating institutions discovered that the rheumatoid arthritis drug auranofin can potentially be repurposed to improve diabetes-associated symptoms.

14 Oct 2022

Rapidly fading antibody levels in recovered COVID-19 patients associated with plasma metabolites

A study led by Hong Kong Baptist University (HKBU) has revealed the association between rapidly fading antibody levels in some recovered COVID-19 patients and a high plasma concentration of a metabolite called glycylproline (gly-pro) and its producing enzyme.

14 Oct 2022

Mouse model reveals how RNA splicing defects contribute to neurodegeneration in Alzheimer's disease

Researchers have puzzled over the neurodegenerative disorder Alzheimer's disease for decades, but treatments to stop or reverse the disease's effects on the brain have remained elusive.

13 Oct 2022

Researchers identify brain cells responsible for shifts in the sleep-wake rhythm

A research team of the Center for Brain Research at the Medical University of Vienna has identified a specific cell group in the brain responsible for shifts in the sleep-wake rhythm caused by psychostimulants.

11 Oct 2022

Study provides new insights into the origin and development of B cells

B cells and the antibodies they produce play an important role in our immune system, protecting us from the microscopic enemies that make us ill.

11 Oct 2022

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Researchers established a neonatal mice model that enabled SARS-CoV-2 transmission.

7 Oct 2022

Study opens avenues to improve prognosis of children with congenital hypogonadotropic hypogonadism

Congenital hypogonadotropic hypogonadism is a rare disease characterized by delayed puberty or the complete absence of puberty in adolescence, leading to infertility.

5 Oct 2022

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Researchers demonstrated that tumor cells evade immunotherapy by generating unique transient cell-in-cell structures, resistant to chemotherapy and destruction by T cells.

5 Oct 2022

Omicron reduces host antibody response by lower B-cell antigenicity

A new study explores the functional relevance of some Omicron mutations in terms of their ability to escape neutralizing antibody responses.

4 Oct 2022

Newly identified mechanism may explain why women are more vulnerable to Alzheimer's disease

Case Western Reserve University researchers have identified a mechanism in brain tissue that may explain why women are more vulnerable to Alzheimer's disease - a finding that they say could help lead to new medicines to treat the disease.

4 Oct 2022

Enzyme found to play a crucial role in guiding cellular response to stress

An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests.

3 Oct 2022

The sexual dimorphisms in the epidemiology and pathophysiology of obesity

Researchers reviewed the sexual dimorphisms in obesity.

30 Sep 2022

Mouse Model News and Research

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Commensal gut microbes from IBD patients produce genotoxic metabolites

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Cells in the brain's blood vessels necessary for fever reaction

Study identifies an animal model that shares many similarities with progressive MS

Researchers identify specific T cell required to bolster vaccine immunity against fungal pneumonia

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

Structure of the irregular neuronal connection strengths contains a hidden order, study finds

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

Rapidly fading antibody levels in recovered COVID-19 patients associated with plasma metabolites

Mouse model reveals how RNA splicing defects contribute to neurodegeneration in Alzheimer's disease

Researchers identify brain cells responsible for shifts in the sleep-wake rhythm

Study provides new insights into the origin and development of B cells

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Study opens avenues to improve prognosis of children with congenital hypogonadotropic hypogonadism

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Omicron reduces host antibody response by lower B-cell antigenicity

Newly identified mechanism may explain why women are more vulnerable to Alzheimer's disease

Enzyme found to play a crucial role in guiding cellular response to stress

The sexual dimorphisms in the epidemiology and pathophysiology of obesity

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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