Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Gene therapy offers potential cure for patients with lipoprotein lipase deficiency

During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the first patient to receive the treatment had no abdominal pain or episodes of pancreatitis, following a history of 37 pancreatitis attacks.

2 May 2018

Researchers uncover how obesity leads to cancer in epithelial cells

A new study led by researchers at Hokkaido University has shown that obesity may enhance the progression of cancer, while aspirin may protect against it.

26 Apr 2018

Alcohol damages microbiome in the mouth

A new study has shown that alcohol alters and damages the natural bacterial environment in the mouth. The study titled, “Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults,” published this week (24th April 2018) in the journal Microbiome explored the effects of alcohol on these bacterial compositions within the mouth.

25 Apr 2018

Scientists discover culprit in reducing effectiveness of insulin

Scientists at Osaka University discovered that Stromal derived factor-1 (SDF-1) secreted from adipocytes reduced the effectiveness of insulin in adipocytes and decreased insulin-induced glucose uptake.

25 Apr 2018

New implantable device furnishes islet cells with their own supply of oxygen

Since the 1960s, researchers have been interested in the possibility of treating type 1 diabetes by transplanting islet cells -- the pancreatic cells that are responsible for producing insulin when blood glucose concentration increases.

25 Apr 2018

Bariatric surgery successes pave way for new type 2 diabetes treatment

Bariatric surgery has long yielded almost immediate health benefits for patients with type 2 diabetes, and new findings on the reasons for remission may be the key to developing drug alternatives to surgery.

25 Apr 2018

Hacking 'drug trafficking' system could increase effectiveness of diabetes treatment

Making tiny changes to existing diabetes treatments can alter how they interact with cells, and potentially make the medicines more effective.

23 Apr 2018

Tattoo sensor: A needleless glucose monitor for diabetes patients

For Angela Valdez, being diagnosed with diabetes was an awakening. The disorder ran in her family, but she didn't think it would happen to her. And when it did, she acted by modifying her diet and physical activity. She was doing everything right--almost.

20 Apr 2018

Gene affects some women's body fat distribution and increases their diabetes risk

A natural variation of the gene KLF14 causes some women to store fat on their bellies and hips and puts them at significantly increased risk of type 2 diabetes, new research reveals.

17 Apr 2018

Study: Hot spots of type 1 diabetes found in food swamps

Hot spots of type 1 diabetes in New York City are found in food swamps, areas with a higher proportion of fast food restaurants, for children and adults with type 1 diabetes according to a new study published in the Endocrine Society's Journal of the Endocrine Society.

17 Apr 2018

Scientists provide insight into how gene associated with autoimmunity contributes to disease

Researchers have provided new insight into how a gene associated with autoimmunity contributes to disease in humans.

17 Apr 2018

Researchers discover potential hurdle for personalized medicine

A recent study has shown that loss of the Erk oncogene can stimulate tumorigenesis in cells where Ras has been eliminated. The findings may have important consequences for the development of personalized medicines that target Ras.

17 Apr 2018

Pancreatitis risk in minorities linked to alcohol, gallstones and high triglycerides

Pancreatitis in ethnic minorities is linked to very high levels of triglycerides and the risk is further increased by alcohol abuse and gallstones, according to a study published in the journal Endocrine Practice.

16 Apr 2018

Specific small-bowel microbes regulate digestion and absorption of fats, study shows

Although the vast majority of research on the gut microbiome has focused on bacteria in the large intestine, a new study - one of a few to concentrate on microbes in the upper gastrointestinal tract - shows how the typical calorie-dense western diet can induce expansion of microbes that promote the digestion and absorption of high-fat foods.

11 Apr 2018

Pancreas News and Research

Further Reading

Gene therapy offers potential cure for patients with lipoprotein lipase deficiency

Researchers uncover how obesity leads to cancer in epithelial cells

Alcohol damages microbiome in the mouth

Scientists discover culprit in reducing effectiveness of insulin

New implantable device furnishes islet cells with their own supply of oxygen

Bariatric surgery successes pave way for new type 2 diabetes treatment

Hacking 'drug trafficking' system could increase effectiveness of diabetes treatment

Tattoo sensor: A needleless glucose monitor for diabetes patients

Gene affects some women's body fat distribution and increases their diabetes risk

Study: Hot spots of type 1 diabetes found in food swamps

Scientists provide insight into how gene associated with autoimmunity contributes to disease

Researchers discover potential hurdle for personalized medicine

Pancreatitis risk in minorities linked to alcohol, gallstones and high triglycerides

Specific small-bowel microbes regulate digestion and absorption of fats, study shows

Mice study reveals important role of pTreg cell population in autoimmune diabetes

Novel technology gives rise to mouse pancreatic tumors that resemble human cancer

Researchers develop improved method for calculating type 1 diabetes risk

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

Previously unknown feature of human anatomy identified

UC researcher granted patent for potential pulmonary infection treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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