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Bioengineered uterine tissue can support normal pregnancies, study shows

In new research from the Wake Forest Institute for Regenerative Medicine (WFIRM), scientists have shown that bioengineered uteri supported fertilization, fetal development, and live birth with normal offspring.

29 Jun 2020

Innovative technology permits faster, cheaper toxicological screening of drug candidates

Ramot at Tel Aviv University has signed a collaboration agreement with Bayer to develop and validate a platform for in vitro cardiotoxicity screening, using human heart tissues 3D-printed in Prof. Tal Dvir's Laboratory for Tissue Engineering and Regenerative Medicine at Tel Aviv University.

29 Jun 2020

New eye drops could prevent vision loss after retinal vein occlusion

Researchers at Columbia University Irving Medical Center have developed eye drops that could prevent vision loss after retinal vein occlusion, a major cause of blindness for millions of adults worldwide.

29 Jun 2020

Biophysicists propose a simple way to observe heart tissue

Biophysicists from the Moscow Institute of Physics and Technology and their colleagues have proposed a simple way to observe the heart tissue.

29 Jun 2020

Clinically approved drugs could disrupt SARS-CoV-2 from hijacking cells

An international team of researchers has analyzed how SARS-CoV-2, the virus that causes COVID-19, hijacks the proteins in its target cells.

29 Jun 2020

NUS researchers discover protein that promotes cancer progression

Cancers arise when the genetic code of normal cells is altered, causing excessive growth. Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a protein that drives the growth of cancers of the esophagus or liver by altering the genetic code in a novel way.

29 Jun 2020

Integrating pharmacists into GP practices can optimize treatment plans in primary care

Research undertaken by RCSI University of Medicine and Health Sciences suggests that integrating pharmacists into general practice (GP) teams facilitates collaboration to optimize treatment plans for patients with long-term medical needs and alleviate pressures on GP practices.

29 Jun 2020

New polymeric heart valve is a promising alternative for valve replacement surgery, study shows

A new polymeric heart valve with a life span potentially longer than current artificial valves that would also prevent the need for the millions of patients with diseased heart valves to require life-long blood thinning tablets has been developed by scientists at the universities of Bristol and Cambridge.

29 Jun 2020

Smart MRI scan used for heart disease can help assess aggressive cancers in children

A type of smart MRI scan used in people with heart disease could help assess whether children's cancers are especially aggressive and spot early signs that targeted treatments are working, a new study suggests.

29 Jun 2020

Study identifies small molecule inhibitors of SARS-CoV-2 which block key cellular kinases

Antiviral drug screen of kinase inhibitors, which was done by researchers from the University of California and Cedars-Sinai Medical Center, identified cellular signaling pathways critical for SARS-CoV-2 replication and revealed an important mechanism of host-pathogen interaction vital for further drug research. Their results are available on the bioRxiv* preprint server.

28 Jun 2020

A novel strategy to achieve site-selective chiral drug synthesis in living systems

Enantioselectivity plays an important role in the pharmacological and toxicological processes of chiral drugs.

26 Jun 2020

WFIRM and Oracle Health Sciences team up to pair Body-on-a-Chip with data analytics

The Wake Forest Institute for Regenerative Medicine and Oracle Health Sciences have teamed as part of the Innovation Quarter's iQ Healthtech Labs to develop a consortium of industry, government, and academic members that will study novel approaches to establishing the safety of new drugs that are nearing clinical investigation in humans and FDA approval.

26 Jun 2020

New steroid compounds from deep-water starfish show anticancer activity

Russian scientists from Far Eastern Federal University, G. B. Elyakov Pacific Institute of Bioorganic Chemistry, and A.V. Zhirmunsky National Scientific Center for Marine Biology have discovered four new steroid substances which target cells of human breast cancer, and colorectal carcinoma.

26 Jun 2020

Physician prescribing of muscle relaxants has tripled from 2005 to 2016, study shows

Office visits for ongoing prescribing of skeletal muscle relaxant drugs tripled from 2005 to 2016, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

26 Jun 2020

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

Researchers from the University of California, Irvine, in collaboration with their colleagues from Beijing, China, have gained new insights into the development of poorly understood malignant skin cancers collectively known as Paget's disease.

26 Jun 2020

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

PrecisionLife’s unique AI platform has found 68 genes associated with risk of developing severe COVID-19 after analysis of the genomes of 929 patients from the UK Biobank who had a severe response to SARS-CoV-2.

26 Jun 2020

International study uncovers three molecules with potential for treating epilepsy

A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy.

26 Jun 2020

Study shows how two proteins provide a tunnel for bad cholesterol to enter the cells

A study has outlined how two proteins are instrumental to bringing cholesterol into cells – a finding that has implications for a range of diseases.

26 Jun 2020

Vitamin D supplements may help prevent serious side effect of anti-cancer therapy

New research indicates that taking vitamin D supplements may help prevent a potentially serious side effect of a revolutionary form of anti-cancer therapy. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

26 Jun 2020

Fatalities are very rare in children with COVID-19

Children with COVID-19 generally experience a mild disease and fatalities are very rare, according to a study of 582 patients from across Europe published today in The Lancet Child & Adolescent Health journal.

26 Jun 2020

Drugs News and Research

Bioengineered uterine tissue can support normal pregnancies, study shows

Innovative technology permits faster, cheaper toxicological screening of drug candidates

New eye drops could prevent vision loss after retinal vein occlusion

Biophysicists propose a simple way to observe heart tissue

Clinically approved drugs could disrupt SARS-CoV-2 from hijacking cells

NUS researchers discover protein that promotes cancer progression

Integrating pharmacists into GP practices can optimize treatment plans in primary care

New polymeric heart valve is a promising alternative for valve replacement surgery, study shows

Smart MRI scan used for heart disease can help assess aggressive cancers in children

Study identifies small molecule inhibitors of SARS-CoV-2 which block key cellular kinases

A novel strategy to achieve site-selective chiral drug synthesis in living systems

WFIRM and Oracle Health Sciences team up to pair Body-on-a-Chip with data analytics

New steroid compounds from deep-water starfish show anticancer activity

Physician prescribing of muscle relaxants has tripled from 2005 to 2016, study shows

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

International study uncovers three molecules with potential for treating epilepsy

Study shows how two proteins provide a tunnel for bad cholesterol to enter the cells

Vitamin D supplements may help prevent serious side effect of anti-cancer therapy

Fatalities are very rare in children with COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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