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FDA grants AGTC $1M for Phase II human clinical trial in alpha-1 antitrypsin deficiency

Applied Genetic Technologies Corporation, a privately-held, clinical stage biotechnology company developing novel systems to deliver human therapeutics, announces that it has received a grant of $1 million from the Food and Drug Administration (FDA Orphan Drugs Program) to fund a Phase II Human Clinical Trial evaluating the safety and efficacy of a treatment for Alpha 1 Antitrypsin Deficiency (AAT), a genetic disease known to result in serious lung and/or liver disease.

17 Sep 2010

Researchers to conduct gene analysis for ankylosing spondylitis

A new study designed to test suspected links between genes and two immune disorders could open the door to better ways to diagnose and treat the conditions that affect a combined total of approximately 2.5 million people in the United States, report scientists at The University of Texas Health Science Center at Houston (UTHealth).

16 Sep 2010

Caregivers at higher risk for PTSD when cancer patients die in hospital

Cancer patients who die in the hospital or an intensive care unit have worse quality of life at the end-of-life, compared to patients who die at home with hospice services, and their caregivers are at higher risk for developing psychiatric illnesses during bereavement, according to a study by researchers at Dana-Farber Cancer Institute.

16 Sep 2010

bluebird bio publishes LentiGlobin gene therapy clinical trial data results

bluebird bio an emerging leader in the development of innovative gene therapies for severe genetic disorders, today announced publication in the journal Nature of its promising Phase 1/2 data highlighting positive results of LentiGlobin gene therapy treatment in a young adult with severe beta-thalassemia, a blood disorder that is one of the most frequent inherited diseases.

16 Sep 2010

Relypsa announces positive results from Phase 2 clinical trial of RLY5016

Relypsa, Inc., a biopharmaceutical company developing non-absorbed polymeric drugs, today announced positive results from the company's PEARL-HF study, a Phase 2 clinical trial of the company's lead compound, RLY5016. These data were presented by Dr. Bertram Pitt, Professor of Medicine Emeritus, Division of Medicine at the University of Michigan School of Medicine, during the Late-Breaking Clinical Trials Session in an oral presentation titled "The PEARL-HF (Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multiple-Dose To Evaluate the Effects of RLY5016 in Heart Failure Patients) Trial" at the 14th Annual Scientific Meeting of the Heart Failure Society of America held in San Diego, CA September 13-15, 2010.

16 Sep 2010

Researchers win $4.1M NIH grant to develop low-cost, ultra-fast DNA sequencing method

A team led by Boston University biomedical engineering researchers has won a $4.1 million, four-year grant from the National Institutes of Health to refine its nanoscale, low-cost, ultra-fast DNA sequencing method that could lead to individual genome sequencing for less than $1,000.

16 Sep 2010

CINJ experts available for discussion during National Prostate Cancer Awareness Month

The Cancer Institute of New Jersey (CINJ) is making experts available to discuss the risks, treatments and prevention options surrounding prostate cancer during September, which is National Prostate Cancer Awareness Month. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.

15 Sep 2010

Medical students should learn about economic forces that affect health care: JAMA

Medical students and residents should receive much more thorough and realistic instruction about the economic forces affecting health care and their own clinical decisions so that they can better serve patients' well-being and the nation's economic welfare, says a commentary published today in a theme issue of the Journal of the American Medical Association, which focuses on improving medical education.

15 Sep 2010

Harvard neurologist starts new program for doctor education; Study finds journal authors often do not disclose ties to medical device companies

The Boston Globe reports on Dr. Martin Samuels, a Harvard Medical School neurologist, who started "a new company that he says will provide continuing medical education to doctors across the country — without funding from the pharmaceutical industry.

15 Sep 2010

Actress joins UTHealth to establish 'John Ritter Research Program in Aortic and Vascular Diseases'

Actress, writer and aortic health advocate Amy Yasbeck has joined with The University of Texas Health Science Center at Houston (UTHealth) to establish the John Ritter Research Program in Aortic and Vascular Diseases (JRRP) to combat the devastating disease that took the life of her husband, legendary comic actor John Ritter.

15 Sep 2010

Educational intervention likely to probe for contextual issues in standardized patient encounters

Fourth-year medical students who participated in an educational intervention were more likely to seek, identify and incorporate into care patient circumstances that may require variation from standard care, compared to students in a control group, according to a study in the September 15 issue of JAMA, a theme issue on medical education.

15 Sep 2010

Resident doctors report working when sick

A new study demonstrates that young doctors often fail to heed the Biblical injunction, "physician, heal thyself." In a research letter published in the September 15, 2010, issue of JAMA, researchers report that three out of five residents surveyed came to work in the previous year while sick, possibly exposing their patients and colleagues to suboptimal performance and, in many cases, communicable disease.

15 Sep 2010

Biomedical informatics is essential part of medical education

In an article published in the Sept. 15 edition of the Journal of the American Medical Association, (JAMA), author Edward H. Shortliffe, MD, PhD, points out that although information underlies all clinical work, and despite the growing role that information management and access play in healthcare delivery and clinical support, there is a dearth of informatics competency being developed in America's future corps of physicians.

15 Sep 2010

Burned-out medical students admit unprofessional conduct in relation to patient care

A Mayo Clinic study involving seven major medical schools shows a majority of medical students surveyed suffer from burnout and that those students were more likely to cheat or be dishonest in relation to patient care. The findings appear in this week's issue of JAMA.

15 Sep 2010

Depression and distress among medical students

Medical students with moderate to severe depression more frequently endorsed several depression stigma attitudes than nondepressed students and had a higher rate of suicidal thoughts, according to a study in the September 15 issue of JAMA, a theme issue on medical education.

15 Sep 2010

Medical students experience high rate of depression than general population: Study

Medical students experience depression at a higher rate than the general population and attach high levels of stigma to the mental illness, according to U-M research to be published Sept. 15 in the Journal of the American Medical Association.

15 Sep 2010

RAB-1 monoclonal antibody study shows positive result for rabies

With the potential to save tens of thousands of lives each year, a new cost-effective rabies therapy developed by MassBiologics at the University of Massachusetts and the Serum Institute of India took an important step forward with positive results from a Phase 1 study. The recently completed study showed that a new monoclonal antibody (RAB-1) resulted in protective antibody levels in the serum of treated subjects equal to the current standard of treatment, which is often not available in the areas of the world hit hardest by rabies.

15 Sep 2010

Researchers create artificial human ovary to yield infertility treatments for cancer patients

Researchers at Brown University and Women & Infants Hospital have invented the first artificial human ovary, an advance that provides a potentially powerful new means for conducting fertility research and could also yield infertility treatments for cancer patients. The team has already used the lab-grown organ to mature human eggs.

15 Sep 2010

Study to identify demographic variables prior to medical school acceptance

Dorothy A. Andriole, M.D., and Donna B. Jeffe, Ph.D., of Washington University, St. Louis, conducted a study to identify demographic variables prior to medical school acceptance associated with outcomes for medical school students.

14 Sep 2010

Anthem Blue Cross and Blue Shield in Connecticut to move from North Haven to Wallingford

Anthem Blue Cross and Blue Shield in Connecticut (Anthem) announced today that they are moving their headquarters from North Haven to Wallingford in 2011. The company has signed a ten year lease with property landlord Workstage-Connecticut, LLC for space in the 300,000-square-foot office building, the Campus at Greenhill, located at 108 Leigus Road. The relocation plan will be in two phases; the first occurring in Sept. 2011, and the second and final phase in Sept. 2012. In all, Anthem will occupy 217,764 square feet of the campus.

14 Sep 2010

Medical School News and Research

FDA grants AGTC $1M for Phase II human clinical trial in alpha-1 antitrypsin deficiency

Researchers to conduct gene analysis for ankylosing spondylitis

Caregivers at higher risk for PTSD when cancer patients die in hospital

bluebird bio publishes LentiGlobin gene therapy clinical trial data results

Relypsa announces positive results from Phase 2 clinical trial of RLY5016

Researchers win $4.1M NIH grant to develop low-cost, ultra-fast DNA sequencing method

CINJ experts available for discussion during National Prostate Cancer Awareness Month

Medical students should learn about economic forces that affect health care: JAMA

Harvard neurologist starts new program for doctor education; Study finds journal authors often do not disclose ties to medical device companies

Actress joins UTHealth to establish 'John Ritter Research Program in Aortic and Vascular Diseases'

Educational intervention likely to probe for contextual issues in standardized patient encounters

Resident doctors report working when sick

Biomedical informatics is essential part of medical education

Burned-out medical students admit unprofessional conduct in relation to patient care

Depression and distress among medical students

Medical students experience high rate of depression than general population: Study

RAB-1 monoclonal antibody study shows positive result for rabies

Researchers create artificial human ovary to yield infertility treatments for cancer patients

Study to identify demographic variables prior to medical school acceptance

Anthem Blue Cross and Blue Shield in Connecticut to move from North Haven to Wallingford

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