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Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration.

15 Aug 2020

COVID-19 pandemic as severe as 1918 influenza pandemic

A recent study published in the journal JAMA Network Open reveals that the excess death toll observed during the initial period of coronavirus disease 2019 (COVID-19) pandemic in New York City is comparable to that observed during the peak of the H1N1 influenza pandemic in 1918.

14 Aug 2020

TGen review: Postmenopausal women at higher risk for developing NALFD

A review article authored by a researcher at the Translational Genomics Research Institute, an affiliate of City of Hope, suggests that following menopause, women are at higher risk for developing nonalcoholic fatty liver disease, a chronic condition caused by the build-up of excess fat in the liver not caused by alcohol.

14 Aug 2020

Back to life: COVID lung transplant survivor tells her story

Mayra Ramirez remembers the nightmares. During six weeks on life support at Northwestern Memorial Hospital in Chicago, Ramirez said, she had terrifying nightmares that she couldn't distinguish from reality.

14 Aug 2020

Preliminary Mayo Clinic results from convalescent plasma in 35,322 patients

A new study published on the preprint server bioRxiv* in August 2020 reports the preliminary results of the US Expanded Access Program (EAP) for CP. The EAP aimed to facilitate access to CP as well as to evaluate the safety of this therapy. However, the current study reports the results of an initial assessment of this agent.

14 Aug 2020

Tiny packages of materials released by tumors may serve as biomarkers for detecting cancers

Because cancer is easier to successfully treat when it's caught early, a major goal in cancer research is to develop new ways to find tumors at early stages, before they start to spread.

13 Aug 2020

Radiation therapy delay for prostate cancer patients offers room for flexibility during the pandemic

For cancer patients receiving radiation treatment during a surge in COVID-19 cases, adhering to the stay-at-home orders of quarantine is not always an option.

13 Aug 2020

Engineered capsids for improved gene delivery to the retina and cornea

A rational design approach created novel variants of adeno-associated viral (AAV) capsids.

13 Aug 2020

Natural controllers shed light on immunity mechanisms against hepatitis B

Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected according to WHO estimates.

13 Aug 2020

JAK inhibitors or type I interferon shown to reduce mortality in COVID-19

Now, a new study by researchers at Yale University and published on the preprint server medRxiv in August 2020 reports that the use of two drug categories, namely, JAK inhibitors and Type I interferons (IFNs), is associated with a dramatic improvement in mortality in COVID-19.

13 Aug 2020

Researchers discover how gut bacteria help the immune system to battle cancerous tumors

Researchers with the Snyder Institute for Chronic Diseases at the Cumming School of Medicine have discovered which gut bacteria help our immune system battle cancerous tumors and how they do it.

13 Aug 2020

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Researchers identify new mechanism that causes leukemia

Every year, 1.1 million new cases of blood cancers are diagnosed worldwide. Presently, chemotherapy remains the most common and effective course of treatment.

13 Aug 2020

Stone age instinct and daily stress have left disproportionate number of women in agony

We're 100% behind knowledge-based research, but sometimes you really do have to question evolution! Jaw-dropping research? Not really, quite the opposite actually!

13 Aug 2020

Neil Bell appointed as Chief Development Officer of Avacta Life Sciences

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce the appointment of Neil Bell as Chief Development Officer of Avacta Life Sciences with immediate effect. Neil will be responsible for late stage pre-clinical and early clinical development of Avacta’s pipeline of pre|CISION pro-drugs and Affimer immunotherapies.

From Avacta Life Sciences Ltd. 13 Aug 2020

Researchers explore association of malaria, HIV with anemia during pregnancy

Pregnant women from sub-Saharan Africa with malaria and human immunodeficiency virus (HIV) have a higher prevalence of anemia than pregnant women without infections according to Penn State College of Medicine researchers.

12 Aug 2020

Combination regimen improves overall survival in certain patients with AML

A combination regimen of venetoclax and azacitidine was safe and improved overall survival (OS) over azacitidine alone in certain patients with acute myeloid leukemia (AML), according to the Phase III VIALE-A trial led by The University of Texas MD Anderson Cancer Center.

12 Aug 2020

Osmotic therapy device reduces swelling in rats with spinal cord injuries

When injured, the spinal cord swells, restricting blood flow, resulting in further, often critical and permanent motor, sensory, and autonomic function damage.

12 Aug 2020

New robotic system can remotely operate ventilators in COVID-19 patient rooms

A new robotic system allows medical staff to remotely operate ventilators and other bedside machines from outside intensive care rooms of patients suffering from infectious diseases.

12 Aug 2020

Yoga improves generalized anxiety disorder, study shows

The feelings of fear are normal emotions felt when the brain senses an impending danger or stress. Anxiety is the body's natural response to stress. In some people, however, they experience constant and overwhelming anxiety and fear, impeding their normal activities.

12 Aug 2020