Enzyme News and Research

RSS

New methods for revealing nerve-muscle activity in live animals

Picking up a pencil, running a marathon, even the simple act of breathing - every time we move a muscle we depend on a series of finely-tuned interactions at the junction of nerve fiber and muscle cell.

20 Apr 2006

Muscles burn lactic acid as well as carbos

In the lore of marathoners and extreme athletes, lactic acid is poison, a waste product that builds up in the muscles and leads to muscle fatigue, reduced performance and pain.

20 Apr 2006

New research links metabolism and appetite suppression, opening door to obesity treatments

A team led by a Canadian researcher has discovered a process by which a small protein acts directly within muscles to increase the body's metabolism to burn fat while simultaneously suppressing appetite.

19 Apr 2006

New tool taps drool for clues to childhood stress

In four separate studies of mothers and their infants, preschoolers, kids and teens, a multi-university research team has shown, for the first time, that a simple test of a little drool can provide new insight into the role of social stressors, including relationships with parents and teachers, in child development.

19 Apr 2006

Scientists document an organ-specific innate immune system

In research published in the April 18 edition of the journal Immunity, scientists at the University of California, San Diego (UCSD) School of Medicine outline the unique mechanism by which the lung shapes its defensive strategies against microbial invasion.

18 Apr 2006

Researchers identify novel agent that protects neurons involved in Parkinson's disease from being destroyed by rotenone

Researchers at the University at Buffalo affiliated with the New York State Center of Excellence in Bioinformatics and Life Sciences have identified a novel agent that can protect neurons involved in Parkinson's disease from being destroyed by the pesticide rotenone.

18 Apr 2006

Possible alternatives found for Vioxx and Celebrex

According to Canadian and American researchers they have identified one reason why drugs like Celebrex and Vioxx - once popular for the treatment of pain and inflammation - cause heart problems.

18 Apr 2006

Researchers clarify the mechanism by which drugs like Celebrex and Vioxx cause heart problems

Researchers at the University of Pennsylvania School of Medicine have clarified the mechanism by which drugs like Celebrex and Vioxx cause heart problems, in multiple animal models.

18 Apr 2006

Nimesulide fights breast cancer by targeting key enzyme

A pain-killing medication appears to halt the production of an enzyme that is key to a common form of breast cancer, a new study using tissue cultures suggests.

16 Apr 2006

First gene therapy human trial in the United States for a form of muscular dystrophy under way

The clinical trial for Duchenne muscular dystrophy (DMD) tests the safety and effectiveness of a therapy that was developed over two decades by scientists at the University of North Carolina Chapel Hill's School of Medicine and the University of Pittsburgh.

16 Apr 2006

Cholesterol-lowering drug might not promote healthy hearts

Antioxidants, such as beta-carotene and Vitamin E, have been touted for their ability to protect against heart disease.

13 Apr 2006

Angiotension-converting enzyme inhibitors may reduce cardiovascular risk

Angiotension-converting enzyme (ACE) inhibitors, medications commonly used to treat hypertension (high blood pressure), may reduce cardiovascular risk and the risk of death in patients with coronary artery disease, according to a new analysis of previously conducted clinical trials reported in the Archives of Internal Medicine.

13 Apr 2006

Simple screening process opens door to treating rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes

Rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes are caused by enzyme deficiencies and typically have crippling, even fatal, consequences starting at very early ages.

13 Apr 2006

Researchers identify the role of a protein in hemoglobin gene silencing

Virginia Commonwealth University Massey Cancer Center researchers have identified the role of a protein in hemoglobin gene silencing that may one day be a potential target for the treatment of genetic blood disorders like sickle-cell anemia and beta-thalassemia on the molecular level.

11 Apr 2006

New model of p53 regulation has important implications for the development of anticancer drugs

Genetically engineered mice convinced scientists at the Salk Institute for Biological Studies that it was time to overhaul widely held beliefs about how a powerful tumor suppressor called p53 is controlled in cells. Their new model of p53 regulation has important implications for the development of anticancer drugs.

11 Apr 2006

St. John's wort and Echinacea increase activity of enzyme in the liver and intestine

St. John's wort and Echinacea, two widely-used herbal preparations, have been found to increase activity of a specific enzyme in the liver and intestine, an enzyme involved in the metabolization of roughly one in every four pharmaceutical drugs on the market today, reports a clinical pharmacologist at Indiana University School of Medicine.

11 Apr 2006

Researchers unravel structure of important new drug target that could potentially treat SARS-infected patients

Mesecar said that the knowledge gained from this new atomic structure - the first-ever reported on this class of proteases - has the potential to go beyond the treatment of patients infected with the coronavirus that causes SARS.

11 Apr 2006

New discovery could help improve some forms of chemotherapy

The research looked at XPB helicase from an archaea, a single cell organism similar to bacteria. Helicases are enzymes that unwind or separate the strands of the nucleic acid double helix, an action that is critical to transcription and nucleotide excision repair (NER), as well as other cell processes.

11 Apr 2006

Whole genome analysis of the protein kinases from Dictyostelium

The journal PLoS Genetics has published the findings of a team of scientists at the nonprofit Boston Biomedical Research Institute that provides a whole genome analysis of the protein kinases from a scientifically valuable model organism known as Dictyostelium.

10 Apr 2006

Discovery of new human retrovirus

Howard Hughes Medical Institute researchers and their colleagues have discovered a new retrovirus in humans that is closely related to a cancer-causing virus found in mice. Their findings describe the first documented cases of human infection with a retrovirus that is native to rodents.

10 Apr 2006

Enzyme News and Research

New methods for revealing nerve-muscle activity in live animals

Muscles burn lactic acid as well as carbos

New research links metabolism and appetite suppression, opening door to obesity treatments

New tool taps drool for clues to childhood stress

Scientists document an organ-specific innate immune system

Researchers identify novel agent that protects neurons involved in Parkinson's disease from being destroyed by rotenone

Possible alternatives found for Vioxx and Celebrex

Researchers clarify the mechanism by which drugs like Celebrex and Vioxx cause heart problems

Nimesulide fights breast cancer by targeting key enzyme

First gene therapy human trial in the United States for a form of muscular dystrophy under way

Cholesterol-lowering drug might not promote healthy hearts

Angiotension-converting enzyme inhibitors may reduce cardiovascular risk

Simple screening process opens door to treating rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes

Researchers identify the role of a protein in hemoglobin gene silencing

New model of p53 regulation has important implications for the development of anticancer drugs

St. John's wort and Echinacea increase activity of enzyme in the liver and intestine

Researchers unravel structure of important new drug target that could potentially treat SARS-infected patients

New discovery could help improve some forms of chemotherapy

Whole genome analysis of the protein kinases from Dictyostelium

Discovery of new human retrovirus

Biochemistry eBook

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Latest Life Science News