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New approaches to genetic disease, based on cells' own ability to correct themselves

New approaches to genetic disease, based on cells' own ability to correct themselves, will be outlined today at the annual conference of the European Society of Human Genetics in Amsterdam, The Netherlands.

8 May 2006

The efficacy and safety of Rituximab in patients with active rheumatoid arthritis

Drugs aimed at suppressing inflammation-provoking cytokines--specifically those linked to T-cells--have improved the treatment of rheumatoid arthritis (RA), a chronic, inflammatory autoimmune disease. Still, the frequency of remission achieved by these biologic agents remains below 50 percent.

3 May 2006

A new fast-melting oral formulation of desmopressin

Vande Walle and colleagues performed this study to determine the pharmacodynamic properties as well as the safety and tolerability of a new oral lyophilisate formulation of desmopressin (in single doses of 30, 60, 120, 240, 360 or 480 µg) in children with known primary nocturnal enuresis (PNE).

3 May 2006

Minority and multiracial children experience many disparities in medical and oral health status

Minority and multiracial children experience many disparities in medical and oral health status, access to care, and use of services, according to a new national study by researchers at the Center for Advancement of Underserved Children at the Medical College of Wisconsin in Milwaukee and Children's Hospital of Wisconsin.

3 May 2006

Periodontitis and plasma C-reactive protein during pregnancy

Researchers found that pregnant women with periodontitis had 65 percent higher C-reactive protein (CRP) levels compared to periodontally healthy women.

3 May 2006

Men find masculine men more threatening during their partner's ovulation phase

Men become more jealous of dominant males when their female partner is near ovulation, researchers at the University of Liverpool have found.

3 May 2006

Enzyme discovery could reduce Kaposi sarcoma tumour growth and lead to drugs suitable for treating other viral cancers

A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth. This discovery could result in the production of new drugs to treat this and other viral cancers.

28 Apr 2006

Finding indicate why some kinds of Leukemia are more aggressive than others

New clues to why some kinds of leukemia are more aggressive and deadly than others are coming from research examining the types of genetic damage that allow some blood cells to grow out of control, scientists report.

28 Apr 2006

Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia

23 Apr 2006

No alarm on fluoride: cancer risk unproven

Suggestions that fluoridated water supplies may be linked to a rare form of bone cancer have not been scientifically established, Victoria's Chief Health Officer Dr Robert Hall said this week.

20 Apr 2006

Tongue scraping for treating halitosis

Despite widespread use of mouthwashes, breath mints, sprays, chewing gums and mechanical tongue cleaning, research is inconclusive about which method is most effective at attacking bad breath, investigators conclude in a new review of clinical studies.

18 Apr 2006

Oral misoprostol for induction of labour

A popular anti-ulcer pill used around the world for inducing labor and preventing post-delivery bleeding appears to be as effective as more expensive drugs but still must be used with caution, according to an updated systematic review of studies.

18 Apr 2006

Certain soil types serve as natural prion repositories in the wild

Scientists have confirmed that prions, the mysterious proteins thought to cause chronic wasting disease (CWD) in deer, latch on tightly to certain minerals in soil and remain infectious.

18 Apr 2006

Saccharide complexes improve binding of Pentosanpolysulfate and Heparin to bladder epithelium

Anionic glycosaminoglycans including pentosanpolysulphate (PPS) and heparin show weak or no staining of the bladder epithelium and thus do not bind to human or rabbit bladder epithelium in any appreciable amounts.

17 Apr 2006

Mass vaccination in Bangladesh to halt the spread of Polio

The recent re-emergence of polio in Bangladesh has prompted a vaccination campaign aimed at as many as 18 million children the age of 5.

17 Apr 2006

Antibiotic telithromycin is effective at treating acute asthma attacks

Researchers have demonstrated that an antibiotic is effective at treating acute asthma attacks, potentially providing a new way to help asthma sufferers.

13 Apr 2006

Computer program lets people with Trigeminal neuralgia diagnose themselves

Trigeminal neuralgia, or TN, is a disorder affecting the areas of the face where the trigeminal nerve's branches are distributed, including the lips, eyes, nose, scalp, forehead, and upper and lower jaws.

13 Apr 2006

Environmental scientists identify new culprits in the cancer equation

In the granite-rich region of Western North Carolina, taking a daily shower could pose a risk of developing lung cancer. So could working from home every day. That's because granite emits a carcinogenic gas, radon.

13 Apr 2006

Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy

The patient of a periodontist in private practice in New Orleans developed osteonecrosis of the jaw (ONJ), a condition that can cause severe, often irreversible and debilitating damage to the jaw, following periodontal surgical therapy.

11 Apr 2006

St. John's wort and Echinacea increase activity of enzyme in the liver and intestine

St. John's wort and Echinacea, two widely-used herbal preparations, have been found to increase activity of a specific enzyme in the liver and intestine, an enzyme involved in the metabolization of roughly one in every four pharmaceutical drugs on the market today, reports a clinical pharmacologist at Indiana University School of Medicine.

11 Apr 2006

Oral News and Research

New approaches to genetic disease, based on cells' own ability to correct themselves

The efficacy and safety of Rituximab in patients with active rheumatoid arthritis

A new fast-melting oral formulation of desmopressin

Minority and multiracial children experience many disparities in medical and oral health status

Periodontitis and plasma C-reactive protein during pregnancy

Men find masculine men more threatening during their partner's ovulation phase

Enzyme discovery could reduce Kaposi sarcoma tumour growth and lead to drugs suitable for treating other viral cancers

Finding indicate why some kinds of Leukemia are more aggressive than others

Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia

No alarm on fluoride: cancer risk unproven

Tongue scraping for treating halitosis

Oral misoprostol for induction of labour

Certain soil types serve as natural prion repositories in the wild

Saccharide complexes improve binding of Pentosanpolysulfate and Heparin to bladder epithelium

Mass vaccination in Bangladesh to halt the spread of Polio

Antibiotic telithromycin is effective at treating acute asthma attacks

Computer program lets people with Trigeminal neuralgia diagnose themselves

Environmental scientists identify new culprits in the cancer equation

Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy

St. John's wort and Echinacea increase activity of enzyme in the liver and intestine

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