Genes News and Research

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Medicare fails to recover hundreds of millions of dollars in lab overcharges

Five years ago, Companion DX Reference Lab hoped to cash in on cutting-edge genetic tests paid for by Medicare.

15 Dec 2017

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

A new study led by scientists at the University of Southampton has found that inherited variation in a particular gene may be to blame for the lower survival rate of patients diagnosed with early-onset breast cancer.

14 Dec 2017

Many food-induced anaphylaxis cases in children occur under adult supervision

At least a third of reactions in children with food-induced anaphylaxis to a known allergen occur under adult supervision, according to a new study led by AllerGen researchers in Quebec, Ontario and Alberta.

14 Dec 2017

Study tests accuracy of laboratory-developed cancer tests and FDA-approved companion diagnostics

Cancer molecular testing can drive clinical decision making and help a clinician determine if a patient is a good candidate for a targeted therapeutic drug.

14 Dec 2017

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

A fusion gene is a single composite gene that is the result of the combination of two formerly independent genes. Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun.

14 Dec 2017

Scientists unravel mystery of how immune cells remember infections decades later

A perplexing question in immunology has been, how do immune cells remember an infection or a vaccination so that they can spring into action decades later? Research led by scientists at the University of California, Berkeley, in collaboration with investigators at Emory University, has found an answer: A small pool of the same immune cells that responded to the original invasion remain alive for years, developing unique features that keep them primed and waiting for the same microbe to re-invade the body.

14 Dec 2017

Researchers win NIH grants for Alzheimer's research on Amish resilience and rapid onset

Researchers from Case Western Reserve University School of Medicine have received two grant awards, in partnership with investigators from other institutions, from the National Institutes of Health to conduct major studies on Alzheimer's disease, the most common form of memory loss and other forms of dementia in older persons.

14 Dec 2017

Genetic variations may help identify people at high-risk for chronic pain after surgery

Genetics may play a role in determining whether patients experience chronic pain after surgery, suggests a study published today in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists

14 Dec 2017

Studies reveal possibility for memory T cells to serve a dual purpose

Scientists of two new complementary studies researching mice and humans claim that they have the strongest evidence yet that memory T cells responsible for long-term immune protection also serve an additional role.

14 Dec 2017

Study finds social stigma as barrier to successful treatment of children with HIV in Ethiopia

The social stigma surrounding HIV is still strong in many parts of the world. Children living with HIV in Ethiopia are at high risk of receiving inadequate treatment - or no treatment at all - on account of deeply rooted prejudice.

14 Dec 2017

New blood test accurately forecasts advanced heart failure patients’ survival after surgery

An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for people with advanced heart failure who had surgery to implant mechanical circulatory support devices.

14 Dec 2017

20% of young colon cancer patients have inherited genetic abnormality, research finds

As doctors grapple with increasing rates of colorectal cancers in young people, new research from the University of Michigan may offer some insight into how the disease developed and how to prevent further cancers.

13 Dec 2017

Targeted lung cancer treatments may benefit smokers and non-smokers alike

Smokers are less likely than non-smokers to have lung cancers caused by targetable genetic changes. But a study published this week in the journal Clinical Cancer Research shows that when they do, smokers benefit just as much as non-smokers from targeted treatments.

13 Dec 2017

Mitochondrial error-correction mechanism essential for energy production of cells

Mitochondria generate most of the energy cells need through a respiratory chain for which they must produce their own proteins.

13 Dec 2017

New finding demonstrates what happens at cellular level during onset of type2 diabetes

Researchers at Dublin City University and their project partners in the EU FP7 funded DEXLIFE project have found fresh evidence to explain the processes that occur in the body's cells leading to the onset of type2 diabetes.

12 Dec 2017

New study explains why one identical twin more at risk for autoimmune diseases

It does not matter if you raise them the same, feed them the same, or dress them the same, any parent with identical twins knows their two children are remarkably different. Identical twins are identical in genes, but they are not identical in gene expressions, a difference due to epigenetics.

12 Dec 2017

Study identifies potassium as key to circadian rhythms in red blood cells

An innovative new study from the University of Surrey and Cambridge's MRC Laboratory of Molecular Biology, published in the prestigious journal Nature Communications, has uncovered the secrets of the circadian rhythms in red blood cells and identified potassium as the key to unraveling the mystery.

12 Dec 2017

Hidden genes hold blueprints for designing new anti-cancer drugs

New research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds.

12 Dec 2017

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Genes News and Research

Medicare fails to recover hundreds of millions of dollars in lab overcharges

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

Many food-induced anaphylaxis cases in children occur under adult supervision

Study tests accuracy of laboratory-developed cancer tests and FDA-approved companion diagnostics

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

Scientists unravel mystery of how immune cells remember infections decades later

Researchers win NIH grants for Alzheimer's research on Amish resilience and rapid onset

Genetic variations may help identify people at high-risk for chronic pain after surgery

Studies reveal possibility for memory T cells to serve a dual purpose

Study finds social stigma as barrier to successful treatment of children with HIV in Ethiopia

New blood test accurately forecasts advanced heart failure patients’ survival after surgery

20% of young colon cancer patients have inherited genetic abnormality, research finds

Targeted lung cancer treatments may benefit smokers and non-smokers alike

Mitochondrial error-correction mechanism essential for energy production of cells

New finding demonstrates what happens at cellular level during onset of type2 diabetes

New study explains why one identical twin more at risk for autoimmune diseases

Study identifies potassium as key to circadian rhythms in red blood cells

Hidden genes hold blueprints for designing new anti-cancer drugs

Researchers find new role for SHARPIN protein in melanoma growth

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

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