Oral News and Research

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High levels of a salivary protein IL-1-beta associated with increased bone loss

Researchers at the University at Buffalo have identified two components of saliva that may serve as the basis for novel tests to determine the risk for future loss of the bone that holds teeth in place.

13 Mar 2006

RvE1 protects from inflammation and bone loss in experimental periodontitis

Gum disease is initiated by bacteria populating dental plaque and may eventually result in tissue and tooth loss.

13 Mar 2006

Photodynamic therapy may be an effective treatment for infections of the oral cavity

Researchers found that the bacteria S. mutans, as well as fungal organisms of the genus Candida, cultured from HIV patients, were highly susceptible to killing with minimal doses of PDT, both in laboratory dishes and on biofilms grown on denture material.

13 Mar 2006

Early periodontal treatment leads to lower medical costs

Chronic conditions such as diabetes mellitus (DM), coronary artery disease (CAD), and cerebrovascular disease (CVD) have been associated with periodontal disease.

9 Mar 2006

Saliva RNA test for oral cancer

Oral cancer is the 6th most common cancer in men and the 14th most common cancer in women. In the US, oral cancer will be diagnosed in an estimated 30,000 Americans this year and will cause more than 8,000 deaths.

9 Mar 2006

Repligen commences phase 2 trial of RG2417 for bipolar depression

Repligen Corporation today announced that the Company has initiated a Phase 2 clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar depression.

9 Mar 2006

Lilly launches phase III trial of Enzastaurin

One of the deadliest and rarest forms of cancer is the focus of a Phase III study initiated by Eli Lilly and Company today.

9 Mar 2006

Antibiotic not sufficient for treating trachoma in populations with high disease prevalence

Treating trachoma, an eye infection that can lead to blindness, with a single mass antibiotic distribution in Ethiopian communities with high prevalence of infection is not effective in eliminating the disease

9 Mar 2006

Relationship between periodonta treatment and overall cost of care for several diseases

Chronic conditions such as diabetes mellitus (DM), coronary artery disease (CAD), and cerebrovascular disease (CVD) have been associated with periodontal disease.

8 Mar 2006

Catheter ablation for chronic atrial fibrillation improves quality of life

People who have endured the effects and risks of an irregular heartbeat for years can get long-lasting relief from a procedure that takes less than two hours, a definitive new study shows.

7 Mar 2006

Data from Novogen inflammatory bowel disease drug Phase I clinical trial shows promise

A recently completed Phase 1 clinical trial of an investigational drug to treat inflammatory bowel disease has demonstrated rapid absorption indicating potential for development as an oral therapy.

6 Mar 2006

Individualized treatment options for rosacea

Many individuals who are struggling with redness, pimples and visible blood vessels on their face may incorrectly diagnose their condition as acne, sunburn or sensitive skin.

6 Mar 2006

FDA gives greenlight for new treatment of head and neck cancer

The U.S. Food and Drug Administration has approved colon cancer drug Erbitux to treat head and neck cancer after results of a large clinical trial showed the drug prolonged survival by 20 months.

5 Mar 2006

Effective oral treatment of erectile dysfunction can improve relationships

The inability to perform sexually can have a significant negative psychosocial impact on a man's overall health including depression, anxiety, and low self-esteem.

1 Mar 2006

Concerta used to treat ADHD may be less likely to be abused than other stimulant drugs

A team led by Massachusetts General Hospital (MGH) researchers has found that a delayed-release stimulant used to treat attention-deficit hyperactivity disorder (ADHD) may be less likely to be abused than other stimulant drugs.

1 Mar 2006

Link between rheumatoid arthritis and cancer examined

Rheumatoid arthritis is an inflammatory disease of the immune system and is thought to be linked to an increased risk of cancers of the lymphatic system.

28 Feb 2006

Oral agent alendronate may help men with prostate cancer suffering from bone loss

Men with prostate cancer who experience bone loss from cancer treatment could benefit from a weekly oral therapy commonly given to women with osteoporosis, according to a study presented by the University of Pittsburgh Medical Center (UPMC) at the American Society of Clinical Oncology Prostate Cancer Symposium, Feb. 24 to 26 at the San Francisco Marriott.

27 Feb 2006

Smoking increases risk for root canal treatment

According to a new study appearing in the April issue of the Journal of Dental Research, cigarette smoking can lead to not only tooth discoloration and gum disease, but also a common dental procedure that helps to heal a diseased tooth--the root canal.

27 Feb 2006

Study associates chronic, severe inflammation with increased lymphoma risk among RA patients

An inflammatory disease of the immune system, rheumatoid arthritis (RA) is associated with increased occurrence of lymphoma--or cancers of the lymphatic system, which plays an integral role in the body's ability to fight infection.

27 Feb 2006

Relationship between periodontal disease, obesity and insulin

The relationship between periodontal disease, obesity and insulin resistance was examined in the Third National Health and Nutrition Examination Survey (NHANES III).

23 Feb 2006

Oral News and Research

High levels of a salivary protein IL-1-beta associated with increased bone loss

RvE1 protects from inflammation and bone loss in experimental periodontitis

Photodynamic therapy may be an effective treatment for infections of the oral cavity

Early periodontal treatment leads to lower medical costs

Saliva RNA test for oral cancer

Repligen commences phase 2 trial of RG2417 for bipolar depression

Lilly launches phase III trial of Enzastaurin

Antibiotic not sufficient for treating trachoma in populations with high disease prevalence

Relationship between periodonta treatment and overall cost of care for several diseases

Catheter ablation for chronic atrial fibrillation improves quality of life

Data from Novogen inflammatory bowel disease drug Phase I clinical trial shows promise

Individualized treatment options for rosacea

FDA gives greenlight for new treatment of head and neck cancer

Effective oral treatment of erectile dysfunction can improve relationships

Concerta used to treat ADHD may be less likely to be abused than other stimulant drugs

Link between rheumatoid arthritis and cancer examined

Oral agent alendronate may help men with prostate cancer suffering from bone loss

Smoking increases risk for root canal treatment

Study associates chronic, severe inflammation with increased lymphoma risk among RA patients

Relationship between periodontal disease, obesity and insulin

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