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Vercise DBS System shows improvement in motor scores for patients with Parkinson's disease

Patients with Parkinson's disease using the Boston Scientific Corporation Vercise DBS (deep brain stimulation) System showed a significant improvement in motor scores according to interim data from the VANTAGE DBS study.

18 Jun 2013

Vanda presents additional data from tasimelteon Phase III studies at ENDO 2013

Vanda Pharmaceuticals Inc. presented additional data today at ENDO 2013, the Endocrine Society's 95th Annual Meeting, demonstrating that tasimelteon can entrain (synchronize) both melatonin and cortisol rhythms.

18 Jun 2013

New study identifies possible treatment to block deposition of calcium in arterial wall

HGPS is a rare genetic disease that affects one in every 4-8 million births. The disease is caused by a spontaneous mutation in one of the two copies (alleles) of the gene LMNA, which codes for lamin A, a protein important for the integrity and function of the envelope surrounding the cell nucleus. The mutation causes incorrect processing of the messenger RNA for lamin proteins, resulting in the synthesis of an anomalous protein, called progerin.

18 Jun 2013

Penn Medicine researchers identify key molecular player in recurrent breast cancer

According to the American Cancer Society, nearly 40,000 women in the United States will succumb to breast cancer this year. Most of these women will die not from the primary tumor but rather tumor recurrence - the reappearance of the disease following treatment.

14 Jun 2013

Study: Stress felt by dad leaves lasting impression on his sperm

Sperm doesn't appear to forget anything. Stress felt by dad-whether as a preadolescent or adult-leaves a lasting impression on his sperm that gives sons and daughters a blunted reaction to stress, a response linked to several mental disorders.

13 Jun 2013

Slowdowns in transport of important molecules may contribute to development of ALS

Slowdowns in the transport and delivery of nutrients, proteins and signaling molecules within nerve cells may contribute to the development of the neurodegenerative disorder ALS, according to researchers at the University of Illinois at Chicago College of Medicine.

13 Jun 2013

Tumor suppressor p53 inactivation and restoration: an interview with Dr. Xin Lu, Ludwig Institute for Cancer Research

Before we talk about p53, it is important to understand why cancer cells are a problem for the body. Cancer cells multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don’t belong.

12 Jun 2013

Massachusetts Eye and Ear enrolls deaf children in new clinical trial of Auditory Brainstem Implant

The Massachusetts Eye and Ear Infirmary, a Harvard Medical School teaching affiliate, is now enrolling a select group of deaf infants and children in a new FDA-approved clinical trial of an Auditory Brainstem Implant.

12 Jun 2013

Sugar ingestion associated with low dopamine release in patients with insulin resistance

Using positron emission tomography (PET) imaging of the brain, researchers have identified a sweet spot that operates in a disorderly way when simple sugars are introduced to people with insulin resistance, a precursor to type 2 diabetes.

11 Jun 2013

Scientists discover how Arc protein helps translate learning into memory

Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons-providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.

10 Jun 2013

People with narcolepsy have increased number of neurons that produce histamine

A new study provides surprising evidence that people with narcolepsy have an increased number of neurons that produce histamine, suggesting that histamine signaling may be a novel therapeutic target for this potentially disabling sleep disorder.

4 Jun 2013

Study: GLT1 protein plays a critical role in cocaine craving

A new study conducted by a team of Indiana University neuroscientists demonstrates that GLT1, a protein that clears glutamate from the brain, plays a critical role in the craving for cocaine that develops after only several days of cocaine use.

3 Jun 2013

Structural biologists capture elusive actin nucleation process

Structural biologists from Rice University and Baylor College of Medicine have captured the first three-dimensional crystalline snapshot of a critical but fleeting process that takes place thousands of times per second in each human cell.

31 May 2013

Study reveals that an epilepsy drug shows promise in preventing noise-induced tinnitus

An epilepsy drug shows promise in an animal model at preventing tinnitus from developing after exposure to loud noise, according to a new study by researchers at the University of Pittsburgh School of Medicine.

28 May 2013

Researchers identify mutations in new genes that might be associated with ALS disease

Researchers at the Stanford University School of Medicine have identified mutations in several new genes that might be associated with the development of spontaneously occurring cases of the neurodegenerative disease known as amyotrophic lateral sclerosis, or ALS.

27 May 2013

Potential new treatment approaches for liver diseases

By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.

24 May 2013

Study highlights human's potential to cultivate compassion

Until now, little was scientifically known about the human potential to cultivate compassion - the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.

24 May 2013

Promising approach to prevent emergence of drug-resistant forms of cancer

Re-routing anti-cancer drugs to the "power plants" that make energy to keep cells alive is a promising but long-neglected approach to preventing emergence of the drug-resistant forms of cancer - source of a serious medical problem, scientists are reporting.

24 May 2013

Research findings reveal promising new anti-addiction drug

Researchers at Johns Hopkins have unraveled the molecular foundations of cocaine's effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice.

23 May 2013

New breakthrough in progeria treatment

Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy, University of Gothenburg, Sweden, indicates that the development of progeria in mice was inhibited upon reducing the production of this enzyme.

21 May 2013

Cell Nucleus News and Research

Vercise DBS System shows improvement in motor scores for patients with Parkinson's disease

Vanda presents additional data from tasimelteon Phase III studies at ENDO 2013

New study identifies possible treatment to block deposition of calcium in arterial wall

Penn Medicine researchers identify key molecular player in recurrent breast cancer

Study: Stress felt by dad leaves lasting impression on his sperm

Slowdowns in transport of important molecules may contribute to development of ALS

Tumor suppressor p53 inactivation and restoration: an interview with Dr. Xin Lu, Ludwig Institute for Cancer Research

Massachusetts Eye and Ear enrolls deaf children in new clinical trial of Auditory Brainstem Implant

Sugar ingestion associated with low dopamine release in patients with insulin resistance

Scientists discover how Arc protein helps translate learning into memory

People with narcolepsy have increased number of neurons that produce histamine

Study: GLT1 protein plays a critical role in cocaine craving

Structural biologists capture elusive actin nucleation process

Study reveals that an epilepsy drug shows promise in preventing noise-induced tinnitus

Researchers identify mutations in new genes that might be associated with ALS disease

Potential new treatment approaches for liver diseases

Study highlights human's potential to cultivate compassion

Promising approach to prevent emergence of drug-resistant forms of cancer

Research findings reveal promising new anti-addiction drug

New breakthrough in progeria treatment

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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