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Eating up to one egg per day may help lower cardiovascular disease risk, research suggests

Researchers have shown how moderate egg consumption can increase the amount of heart-healthy metabolites in the blood, publishing their results today in eLife.

24 May 2022

Comparison of COVID-induced ARDS and sepsis-induced ARDS

In a recent study posted to the medRxiv* preprint server, researchers compared the pathophysiology of coronavirus disease 2019 (COVID-19) and bacterial sepsis-induced acute respiratory distress syndrome (ARDS).

20 May 2022

Kyunurenic acid in cardiovascular therapy

In a recent study posted to the bioRxiv* preprint server, researchers assessed the impact of kynurenic acid on ischemic damage to the heart.

19 May 2022

Associations between mucosal gene expression and microbiome composition in three gastrointestinal disorders

A new study authored by Sambhawa Priya and other researchers offers a detailed look at the interactions between the gut microbiome of humans in health and disease.

19 May 2022

Hormonal shift during menopause changes women’s blood metabolite profile

In midlife, the risk of cardiometabolic diseases increases in women more rapidly than in men. A study performed at the Faculty of Sport and Health Sciences of the University of Jyväskylä shows that changes in blood metabolite profile accompany the shift in sex hormone levels during menopause.

13 May 2022

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Intestinal micro-biodiversity is important for maintaining colorectal and general health. Imbalance in this microenvironment can result in chronic infections, even cancer.

10 May 2022

Fluorescence-based sensing could be a useful tool for monitoring lactate levels in living organisms

Lactate is generated in the body as a byproduct, during normal metabolism and exercise. While considered a useless waste product for a long time, recent studies have shown that lactate can be an indicator for cancer and various other diseases.

10 May 2022

Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

Changes in gut microbiome impact depression

Over the last five years, the effects of the gut microbiome on depression have gained scientific attention, resulting in a significant increase in research papers.

8 May 2022

Marine bioactive compounds against SARS-CoV-2

A new review paper published in the journal Environmental Science and Pollution Research aimed to determine the possibilities of using biologically active compounds derived from various chemical classes of marine organisms against SARS-CoV-2 infection at various stages of the life cycle of the virus.

6 May 2022

Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

The glymphatic system enables the flow of cerebrospinal fluid to the brain tissue, particularly during sleep, enabling the fluid to cleanse the tissue and carry accumulated metabolites with it towards the bloodstream during waking hours.

4 May 2022

Researchers reveal the mechanism of action of century-old BCG vaccine

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world's oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There's even some evidence that it can reduce severity of COVID-19.

4 May 2022

Measuring BMI in a new way can help identify individuals at risk of developing type 2 diabetes

Obesity and excess weight increase the risk of developing type 2 diabetes, but individuals of normal weight can also develop the disease.

3 May 2022

Exercise can have a beneficial effect on factors contributing to NAFLD, study shows

Exercise supports the treatment of non-alcoholic fatty liver disease by impacting on several metabolic pathways in the body, a new study from the University of Eastern Finland shows.

3 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

New method enables the structural analysis of RNA molecules

We live in a world made and run by RNA, the equally important sibling of the genetic molecule DNA. In fact, evolutionary biologists hypothesize that RNA existed and self-replicated even before the appearance of DNA and the proteins encoded by it.

3 May 2022

Intestinal inflammation liberates chemicals that nourish the growth of E. coli in Crohn's disease

A multi-year study of the role of E. coli gut bacteria in Crohn's disease finds that intestinal inflammation liberates chemicals that nourish the bacteria's growth and promotes their ability to cause inflammation.

27 Apr 2022

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and examines the potential and roadblocks in using renewable marine resources in the fight against the coronavirus disease 2019 (COVID-19).

24 Apr 2022

Metabolomics and multi-omics perspective of cancer show promise for finding new treatments

While cancer is a genetic disease, the genetic component is just one piece of the puzzle - and researchers need to consider environmental and metabolic factors as well, according to a research review by a leading expert at the University of Alberta.

22 Apr 2022

How does SARS-CoV-2 infection affect the diversity of the gut microbiome?

Researchers have been investigating differences in the fungal gut microbiome in patients with mild-to-severe coronavirus disease 2019.

22 Apr 2022

Metabolites News and Research

Eating up to one egg per day may help lower cardiovascular disease risk, research suggests

Comparison of COVID-induced ARDS and sepsis-induced ARDS

Kyunurenic acid in cardiovascular therapy

Associations between mucosal gene expression and microbiome composition in three gastrointestinal disorders

Hormonal shift during menopause changes women’s blood metabolite profile

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Fluorescence-based sensing could be a useful tool for monitoring lactate levels in living organisms

Tumors release lactate to force neighboring cells into supporting cancer growth

Changes in gut microbiome impact depression

Marine bioactive compounds against SARS-CoV-2

Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

Researchers reveal the mechanism of action of century-old BCG vaccine

Measuring BMI in a new way can help identify individuals at risk of developing type 2 diabetes

Exercise can have a beneficial effect on factors contributing to NAFLD, study shows

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

New method enables the structural analysis of RNA molecules

Intestinal inflammation liberates chemicals that nourish the growth of E. coli in Crohn's disease

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

Metabolomics and multi-omics perspective of cancer show promise for finding new treatments

How does SARS-CoV-2 infection affect the diversity of the gut microbiome?

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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