Microscopy News and Research

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Discovery of antibodies that may eliminate the need for COVID vaccines

...

11 Sep 2022

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

Using Q-bodies for imaging intracellular proteins in live cells

Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development.

9 Sep 2022

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.

9 Sep 2022

Intelligent fluorescent microscope for imaging biological events in detail

Imagine you're a PhD student with a fluorescent microscope and a sample of live bacteria. What's the best way use these resources to obtain detailed observations of bacterial division from the sample?

9 Sep 2022

All SARS-CoV-2 variants neutralized by a potent new antibody

Researchers describe a mouse model used to generate a VH1-2 heavy chain (HC)- and Vκ1-33 light chain (LC)-based recombinant antibody that broadly neutralized all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the newly emergent Omicron sub-variant BA.5.

9 Sep 2022

Stem cell-derived liver cell model could be a valuable tool for future studies on Ebola virus

Ebola virus causes serious infections in humans and in fatal cases, damage and dysfunction of the liver is often present, suggesting that the liver plays a decisive role in disease outcome.

8 Sep 2022

Pitt researchers describe a pathway by which cells repair damaged lysosomes

Today in Nature, University of Pittsburgh researchers describe for the first time a pathway by which cells repair damaged lysosomes, structures that contribute to longevity by recycling cellular trash.

8 Sep 2022

How does SARS-CoV-2 affect the male genitourinary system?

In a recent paper published in the American Journal of Clinical and Experimental Urology, researchers reviewed existing data on the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male genitourinary (GU) tract.

7 Sep 2022

How does SARS-CoV-2 infection impact fertility in men?

In a recent review published in the journal Endocrines, researchers summarized existing literature findings on the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male reproductive system and fertility.

7 Sep 2022

Researchers identify novel neutralizing monoclonal antibodies against SARS-CoV-2 in vaccinated individuals after wildtype infection

Researchers identified monoclonal antibodies that neutralize SARS-CoV-2 variants.

7 Sep 2022

New and unique technique to brain imaging has potential to save lives

Observing the brain without creating any breaks in the skull is an emerging technology for those studying various brain-related diseases.

5 Sep 2022

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Synexa is an industry-leading biomarker and large molecule bio analytic research service provider. In this interview, NewsMedical speaks with Natalie Strickland, a principal scientist at Synexa, about alternative approaches to flow cytometry.

From Synexa Life Sciences 5 Sep 2022

Novel tool evaluates the contractile force-related state of myotubes

Researchers from Tokyo Metropolitan University have developed a way to characterize the force generated by contracting myotubes, precursors to skeletal muscle fiber, combining electrostimulation and analysis of wrinkles in the silicone substrate on which they are mounted. Existing methods rely on muscle mass or the expression of certain proteins, both not as strongly correlated with muscle strength. Accurate measurement of myotube strength promises more effective screening of drug targets for treating muscle atrophy.

5 Sep 2022

Microscopy News and Research

Discovery of antibodies that may eliminate the need for COVID vaccines

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

Using Q-bodies for imaging intracellular proteins in live cells

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Intelligent fluorescent microscope for imaging biological events in detail

All SARS-CoV-2 variants neutralized by a potent new antibody

Stem cell-derived liver cell model could be a valuable tool for future studies on Ebola virus

Pitt researchers describe a pathway by which cells repair damaged lysosomes

How does SARS-CoV-2 affect the male genitourinary system?

How does SARS-CoV-2 infection impact fertility in men?

Researchers identify novel neutralizing monoclonal antibodies against SARS-CoV-2 in vaccinated individuals after wildtype infection

New and unique technique to brain imaging has potential to save lives

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Novel tool evaluates the contractile force-related state of myotubes

New kind of synapse discovered in neurons’ tiny hairs

Study finds strong evidence for the ability of SARS-CoV-2 to infect human sperm in vitro

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

Inactivation of particular protein complex associated with Parkinson's and anxiety disorders

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

What are the effects of e-cigarettes and their constituents on SARS-CoV-2 infection?

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo