Precision Medicine News and Research

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AI model can accurately identify patients at high risk of undiagnosed structural heart disease

A team of clinicians and scientists from Tempus and Geisinger have found that a new artificial intelligence model can accurately identify patients at increased risk of undiagnosed structural heart disease.

25 May 2022

A digital twin for your immune system

In a recent study posted to the NPJ Digital Medicine journal, researchers illustrated a framework for constructing digital twins of the human immune system.

23 May 2022

A step-by-step plan to create a digital twin of the human immune system

An article published May 20 in Nature Digital Medicine provides a step-by-step plan for an international effort to create a digital twin of the human immune system.

20 May 2022

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

New research from Queen Mary University of London, published in Nature Medicine, has shown that molecular profiling of the diseased joint tissue can significantly impact whether specific drug treatments will work to treat rheumatoid arthritis (RA) patients.

19 May 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.

19 May 2022

Researchers show the feasibility of a comprehensive sequencing approach in pediatric and young adult cancers

New findings from researchers at Memorial Sloan Kettering Cancer Center (MSK) and published today in the journal Nature Communications report the results of using a comprehensive sequencing approach on 114 pediatric, adolescent, and young adult patients with solid tumors.

18 May 2022

Using AI to predict heart attacks

In this interview, we speak to Dr. Damini Dey from Cedars-Sinai Medical Center about their latest research that involved using AI to predict heart attacks.

17 May 2022

Penn study finds low uptake of first mutation-targeted bladder cancer drug

The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

12 May 2022

Prostate cancer patients benefit from precision oncology

Researchers at the University of Bern and University Hospital Bern have achieved a breakthrough in a particularly aggressive form of prostate cancer.

11 May 2022

New classification by ESMO to guide research on treatment de-escalation in oncology

ESMO, the leading professional organization for medical oncology, has developed a new evidence-based classification to guide research and interpretation of data on treatment de-escalation in oncology.

11 May 2022

Cells do a little cleanup before mitosis

MIT researchers have discovered that before cells start to divide, they do a little cleanup, tossing out molecules that they appear not to need anymore.

10 May 2022

T cell behavior informs metastatic melanoma outcomes

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why.

9 May 2022

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a gene mutation present in 20-30% of breast cancer recurrences may have a silver lining, leading to novel treatment opportunities.

9 May 2022

New tool can help researchers interpret the clinical significance of somatic mutations in cancer

Researchers at Children's Hospital of Philadelphia have developed a new tool to help researchers interpret the clinical significance of somatic mutations in cancer.

6 May 2022

Insight into Neurological Diagnosis in Children

In this interview, we speak to Amy Brin, MSN, MA, PCNS-BC, CEO of the Child Neurology Foundation, about the current landscape of neurological diagnosis in children and the importance of helping patients and their families through the diagnosis and treatment process.

6 May 2022

Study evaluates the associations between predisposing risk factors and heart attack in young women

A new Yale-led study has for the first time identified which risk factors are more likely to trigger a heart attack or acute myocardial infarction (AMI) for men and women 55 years and younger.

4 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

Normal-appearing skin of lupus patients predisposed to flares and rashes, study finds

People with lupus have overactive immune systems that attack their own tissue, causing inflammation throughout the body.

3 May 2022

$6 million grant to fund research investigating the role of immune system in heart failure

A new grant for researchers at Washington University School of Medicine in St. Louis will fund research investigating the role of the immune system in heart failure. Finding ways to harness beneficial immune cells could lead to new therapies that encourage the heart to heal after injuries.

2 May 2022

Precision Medicine News and Research

AI model can accurately identify patients at high risk of undiagnosed structural heart disease

A digital twin for your immune system

A step-by-step plan to create a digital twin of the human immune system

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Researchers show the feasibility of a comprehensive sequencing approach in pediatric and young adult cancers

Using AI to predict heart attacks

Penn study finds low uptake of first mutation-targeted bladder cancer drug

Prostate cancer patients benefit from precision oncology

New classification by ESMO to guide research on treatment de-escalation in oncology

Cells do a little cleanup before mitosis

T cell behavior informs metastatic melanoma outcomes

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

New tool can help researchers interpret the clinical significance of somatic mutations in cancer

Insight into Neurological Diagnosis in Children

Study evaluates the associations between predisposing risk factors and heart attack in young women

Researchers create models to study brain metastases that recapitulate the disease

Normal-appearing skin of lupus patients predisposed to flares and rashes, study finds

$6 million grant to fund research investigating the role of immune system in heart failure

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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