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Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

The U.S. Food and Drug Administration today approved Alecensa (alectinib) to treat people with advanced (metastatic) ALK-positive non-small cell lung cancer (NSCLC) whose disease has worsened after, or who could not tolerate treatment with, another therapy called Xalkori (crizotinib).

11 Dec 2015

Oxford University researchers find that a blood test could predict rheumatoid arthritis risk

Scientists have found a marker that can indicate your likelihood of suffering from rheumatoid arthritis (RA) even sixteen years before the condition takes effect. A team from the Kennedy Institute of Rheumatology at Oxford University found that a blood test that looks for antibodies that recognize the protein tenascin-C could reliably show those who will contract the condition.

10 Dec 2015

Dietary sugar may help to treat melanoma

New research from scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) suggests that a rare sugar found in seaweed, mushrooms, seeds and other foods may be able to help treat skin cancer.

9 Dec 2015

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Treatment with the antiplatelet agent prasugrel does not significantly reduce the rate of pain crises or severe lung complications in children with sickle cell disease, according to a report published in the New England Journal of Medicine describing one of the largest and most geographically diverse international clinical trials on sickle cell disease to date.

9 Dec 2015

Children with allergic disease have higher risk of heart disease

Children with allergic disease, particularly asthma and hay fever, have about twice the rate of high blood pressure and high cholesterol, setting them on a course for heart disease at a surprisingly early age, reports a new Northwestern Medicine study.

8 Dec 2015

Macrophages play key role in maintaining healthy arteries after inflammation

Researchers from the University of Toronto have found that a specific cell type plays a key role in maintaining healthy arteries after inflammation. It's a discovery that could provide treatment options for cardiovascular disease -- one of the leading causes of death in Canada.

8 Dec 2015

NEK7 enzyme acts as on-off switch in innate immune system

UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection.

8 Dec 2015

Researchers partner to help personalize cancer care

Researchers at the University of Iowa College of Dentistry are partnering with a private company to develop computer simulations that can help personalize cancer care by predicting how a patient will respond to a drug treatment.

7 Dec 2015

Genetic information of patients with IBD could provide road map for more effective treatments

Genetic variation in patients with inflammatory bowel disease (IBD) appears to play a major role in determining how sick they will become and could provide a road map for more effective treatments.

1 Dec 2015

CMU's David Creswell awarded $3 million NIH grant to explore healthy aging among lonely older adults

The National Institutes of Health has awarded a five-year, $3 million grant to Carnegie Mellon University's David Creswell to study how stress management training can boost healthy aging among lonely older adults.

1 Dec 2015

Air evacuations may pose significant added risk to patients with traumatic brain injury

Over the past 15 years, more than 330,000 U.S. soldiers have suffered a traumatic brain injury (TBI). It is one of the leading causes of death and disability connected to the country's recent conflicts in Afghanistan and Iraq. Many of these patients were evacuated by air from these countries to Europe and the U.S. for further treatment. In general, these patients were flown quickly to hospitals outside the battle zone, where more extensive treatment was available.

1 Dec 2015

Pre-existing asthma may strongly predict future chronic migraine attacks

Pre-existing asthma may be a strong predictor of future chronic migraine attacks in individuals experiencing occasional migraine headaches, according to researchers from the University of Cincinnati, Montefiore Headache Center and Albert Einstein College of Medicine, and Vedanta Research.

30 Nov 2015

Medical professionals compare different treatment methods for Neuromyelitis optica

In the course of a study conducted throughout Germany, medical professionals have compared different treatment methods for Neuromyelitis optica, an inflammatory disease of the central nervous system. It turned out that the best results were not achieved with conventional steroid therapy. Under the auspices of the Ruhr-Universität Bochum and the Hannover Medical School, the team published their findings in the journal Annals of Neurology.

30 Nov 2015

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

In addition to their well established cholesterol lowering benefits, statins also have potent anti-inflammatory, anti-fibrotic and antioxidant effects, which continue to be identified in a wide range of diseases.

30 Nov 2015

Testosterone treatment can benefit men with Type 2 diabetes

Men with Type 2 diabetes who have low testosterone levels can benefit significantly from testosterone treatment.

30 Nov 2015

Seaweed extract shows promise in treating H. pylori-related diseases, gastric cancer

A unique seaweed extract shows promise for the treatment of Helicobacter pylori-related diseases and gastric cancer, according to new research undertaken at the University of Western Australia.

28 Nov 2015

Medical professionals compare different treatment options for Neuromyelitis optica

26 Nov 2015

Researchers successfully combine antibody-drug conjugate with immunotherapy to attack breast cancer cells

To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years. Researchers from the University and University Hospital Basel have now for the first time successfully combined such an antibody-drug conjugate with a therapy that stimulates the immune system to attack tumor cells.

26 Nov 2015

Bile pigment may provide natural protection from heart attacks

New hope in the fight against cardiovascular disease has arrived, following breakthrough research identifying a pigment in our bile which could protect us.

26 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

Inflammation News and Research

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

Oxford University researchers find that a blood test could predict rheumatoid arthritis risk

Dietary sugar may help to treat melanoma

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Children with allergic disease have higher risk of heart disease

Macrophages play key role in maintaining healthy arteries after inflammation

NEK7 enzyme acts as on-off switch in innate immune system

Researchers partner to help personalize cancer care

Genetic information of patients with IBD could provide road map for more effective treatments

CMU's David Creswell awarded $3 million NIH grant to explore healthy aging among lonely older adults

Air evacuations may pose significant added risk to patients with traumatic brain injury

Pre-existing asthma may strongly predict future chronic migraine attacks

Medical professionals compare different treatment methods for Neuromyelitis optica

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

Testosterone treatment can benefit men with Type 2 diabetes

Seaweed extract shows promise in treating H. pylori-related diseases, gastric cancer

Medical professionals compare different treatment options for Neuromyelitis optica

Researchers successfully combine antibody-drug conjugate with immunotherapy to attack breast cancer cells

Bile pigment may provide natural protection from heart attacks

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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