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Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder

People with bipolar disorder have lower levels of certain omega-3 fatty acids that cross the blood-brain barrier compared to those who do not, according to researchers from Penn State College of Medicine and the National Institutes of Health. The finding could have implications for dietary interventions for the disorder.

25 Nov 2015

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Scientists from the University of Leicester have for the first time created a detailed image of a toxin - called pneumolysin - associated with deadly infections such as bacterial pneumonia, meningitis and septicaemia.

25 Nov 2015

UF Health researcher finds simple way to treat immune-related disorder in mice

A University of Florida Health researcher has found a simple, rapid way to treat an immune-related disorder in mice, an approach that could eventually help multiple sclerosis patients after further research.

25 Nov 2015

Novartis announces EC approval of Cosentyx for treatment of ankylosing spondylitis, psoriatic arthritis

Novartis announced today that the European Commission has approved Cosentyx (secukinumab) for the treatment of people living with ankylosing spondylitis (AS) and psoriatic arthritis (PsA). For AS, this is the first new treatment advance in 16 years since the development of the current standard of care, anti-tumor necrosis factor (anti-TNF) therapy.

25 Nov 2015

Fat cells produced from bone marrow may be linked to chronic diseases

Researchers at the University of Colorado Anschutz Medical Campus have found that fat cells produced by stem cells from the bone marrow may be linked to chronic illnesses like diabetes, cardiovascular disease, kidney disease and some cancers.

25 Nov 2015

High-fat diet appears to prompt immune cells to start consuming connections between neurons

When a high-fat diet causes us to become obese, it also appears to prompt normally bustling immune cells in our brain to become sedentary and start consuming the connections between our neurons, scientists say.

24 Nov 2015

People who experience persistent heartburn despite over-the-counter treatments need to check with their doctors

If Thanksgiving makes you wince at the thought of impending heartburn pain, you are probably not alone. But if you experience heartburn more than twice a week despite over-the-counter treatments, a Jefferson expert wants you to check with your doctor. Gastroesophageal Reflux Disease (GERD) Awareness Week is observed each year during the week of Thanksgiving, a fitting time as Americans prepare to indulge in the holiday season.

23 Nov 2015

Brain imaging reveals distinctive aspects of high-inflammation depression

About one third of people with depression have high levels of inflammation markers in their blood. New research indicates that persistent inflammation affects the brain in ways that are connected with stubborn symptoms of depression, such as anhedonia, the inability to experience pleasure.

21 Nov 2015

Roundworm infection increases fertility among women in the Amazon

Parasitic worms can live inside humans gaining nourishment from the food we ingest (roundworms) or from our blood (hook worms), whilst being safe from predators. Although roundworm infections are generally symptomless they are not something any of us would choose to have. However, it has recently been found that infection with roundworm increases a woman's fertility.

20 Nov 2015

Weight-loss surgery improves metabolic health of mothers, but harms offspring later in life

Studies show that weight-loss surgery can boost fertility in women and reduce the risk of pregnancy complications that commonly occur in obese women, such as gestational diabetes and preeclampsia. While weight loss surgery improves the metabolic health of mothers, new findings to be presented at Cardiovascular, Renal and Metabolic Diseases: Physiology and Gender support that such surgery has negative consequences on children born after the procedure.

20 Nov 2015

MCG researchers explore how neurofibromatosis puts young patients at risk for cardiovascular disease

It's a fairly common genetic condition that can surface as a series of dark skin spots and result in a host of maladies from tumors to premature cardiovascular disease. Medical College of Georgia researchers hope their studies of how neurofibromatosis 1, or NF1, can dangerously thicken or thin blood vessel walls will one day help physicians better identify and treat these young patients at cardiovascular risk.

20 Nov 2015

Research findings may lead to potential therapeutic target for treating inflammatory bowel diseases

UT Southwestern Medical Center researchers have shown that a pathogen-sensing molecule plays a vital role in keeping gastrointestinal (GI) systems healthy.

20 Nov 2015

Scientists identify way to sensitize drug-resistant glioblastoma cells to chemotherapy

Scientists from the Virginia Tech Carilion Research Institute and clinicians from Carilion Clinic have discovered how to sensitize drug-resistant human glioblastoma cells to chemotherapy.

20 Nov 2015

BUSM researchers identify new fingerprint of inflammation in obesity-associated type 2 diabetes

There is strong evidence that inflammation promotes obesity-associated type 2 diabetes and diabetes complications. However, clinical trials with anti-inflammatory drugs have only been modestly effective for treating Type 2 diabetes. A new fingerprint of inflammation that may be able to predict which patients with obesity may also develop type 2 diabetes has been identified by Boston University School of Medicine researchers.

19 Nov 2015

Consuming tree nuts may reduce risk of cardiovascular disease, new study finds

A new study published in the American Journal of Clinical Nutrition found that consuming tree nuts, such as walnuts, may lower the risk of cardiovascular disease. After conducting a systematic review and meta-analysis of 61 controlled trials, one of the authors, Michael Falk, PhD, Life Sciences Research Organization, found that consuming tree nuts lowers total cholesterol, triglycerides, LDL cholesterol, and ApoB, the primary protein found in LDL cholesterol.

19 Nov 2015

Johns Hopkins scientists use gene-based tests to distinguish precancerous cysts from harmless cysts

In a "look-back" analysis of data stored on 130 patients with pancreatic cysts, scientists at Johns Hopkins have used gene-based tests and a fixed set of clinical criteria to more accurately distinguish precancerous cysts from those less likely to do harm. The findings may eventually help some patients in real time safely avoid surgery to remove harmless cysts.

18 Nov 2015

Coating implants with certain 'activator' can prevent S. aureus infection

Biofilms frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can cause life-threatening infections. New research at the Sahlgrenska Academy show that coating implants with a certain "activator" can prevent Staphylococcus aureus, the leading cause of hospital-acquired infections, from forming biofilms.

18 Nov 2015

Researchers find ranibizumab drug as effective alternative to laser therapy for treating diabetic retinopathy

In a randomized clinical trial of more than 300 participants, researchers from Johns Hopkins and elsewhere have found that ranibizumab — a drug most commonly used to treat retinal swelling in people with diabetes — is an effective alternative to laser therapy for treating the most severe, potentially blinding form of diabetic retinal disease. Results of the government-sponsored study also show that the drug therapy carries fewer side effects than the currently used laser treatment.

17 Nov 2015

Study shows how parasitic worm infection increases susceptibility to TB

Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study demonstrated that treating the parasite reduces lung damage seen in mice that also are infected with tuberculosis, thereby eliminating the vulnerability to tuberculosis (TB) that the parasite is known to cause.

17 Nov 2015

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis.

17 Nov 2015

Inflammation News and Research

Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

UF Health researcher finds simple way to treat immune-related disorder in mice

Novartis announces EC approval of Cosentyx for treatment of ankylosing spondylitis, psoriatic arthritis

Fat cells produced from bone marrow may be linked to chronic diseases

High-fat diet appears to prompt immune cells to start consuming connections between neurons

People who experience persistent heartburn despite over-the-counter treatments need to check with their doctors

Brain imaging reveals distinctive aspects of high-inflammation depression

Roundworm infection increases fertility among women in the Amazon

Weight-loss surgery improves metabolic health of mothers, but harms offspring later in life

MCG researchers explore how neurofibromatosis puts young patients at risk for cardiovascular disease

Research findings may lead to potential therapeutic target for treating inflammatory bowel diseases

Scientists identify way to sensitize drug-resistant glioblastoma cells to chemotherapy

BUSM researchers identify new fingerprint of inflammation in obesity-associated type 2 diabetes

Consuming tree nuts may reduce risk of cardiovascular disease, new study finds

Johns Hopkins scientists use gene-based tests to distinguish precancerous cysts from harmless cysts

Coating implants with certain 'activator' can prevent S. aureus infection

Researchers find ranibizumab drug as effective alternative to laser therapy for treating diabetic retinopathy

Study shows how parasitic worm infection increases susceptibility to TB

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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