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New review provides an update on management of premenopausal osteoporosis

Osteoporosis, a disease which leads to bone fragility and an increased risk of fractures, is very common among postmenopausal women, affecting around one in three over the age of 50 worldwide.

27 Jul 2020

Two-step targeting strategy can increase clinical translation of nanoparticle-based therapies

Therapy-loaded nanoparticles may be directed to the brain by functionalization with ligands targeting BBB-associated proteins.

27 Jul 2020

Study provides new insights into the host cellular response to SARS-CoV-2 infection

The COVID-19 pandemic caused by the new coronavirus has created an unprecedented public health challenge globally. Little was known about how the infecting cells respond to the virus and how the virus hijacks the host cellular machinery.

27 Jul 2020

Researchers identify TLR7 gene that predisposes elderly patients to severe COVID-19

Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease.

25 Jul 2020

GlobalData: COVID-19 has pushed infectious disease drugs to top therapy area for CSAs

Infectious disease drugs have overtaken oncology as the year’s top therapy area for contract service agreements as companies are shifting their current focus to developing treatments to battle the COVID-19 pandemic.

25 Jul 2020

New study helps identify patients at higher risk of statin-related myopathy

Statins are prescribed to millions of people worldwide to reduce their risks of suffering heart attacks and strokes.

25 Jul 2020

First CAR T-cell therapy for mantle cell lymphoma receives FDA approval

Today's Food and Drug Administration approval of the first CAR T-cell therapy for mantle cell lymphoma represents a key advance for patients with relapsed or treatment-resistant forms of the disease, say Dana-Farber Cancer Institute investigators who helped conduct the decisive clinical trial of the therapy.

24 Jul 2020

Patients with frailty, older age and UTIs have higher risk of developing sepsis

Patients with frailty, older age and urinary tract infections are at greatest risk of developing sepsis following infection consultations in primary care, research has found.

24 Jul 2020

Bacteriophages may play a key role in treating prosthetic joint infections

Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research.

24 Jul 2020

UB study validates a novel pharmacological target for Alzheimer’s disease

A UB study published in the journal Neurotherapeutics has validated a new pharmacological target for Alzheimer's disease.

24 Jul 2020

SphingoTec launches point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction

Diagnostics company SphingoTec GmbH today announced the launch of its IB10 sphingotest® bio-ADM®, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin. Blood levels of bio-ADM® reflect in real-time the functional status of the endothelium, the inner cell sheet of blood vessels.

24 Jul 2020

New model may explain why certain cancer cells are resistant to therapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures.

24 Jul 2020

Novel research determines the prevalence of chronic kidney disease

A new study looking at nearly three decades of data from some 54,000 people has determined that the overall prevalence of chronic kidney disease (CKD) for several racial/ethnic and socioeconomic groups in the United States has stabilized in recent years, except Mexican Americans.

24 Jul 2020

Modulating immunometabolic processes to control lung infection

When drugs to kill microbes are ineffective, host-directed therapy uses the body's own immune system to deal with the infection.

23 Jul 2020

New study seeks to improve treatment options for severe brain injuries

Hyperbaric oxygen therapy involves breathing pure oxygen in a pressurized room or tube, and is commonly used to treat decompression sickness resulting from scuba diving or wounds that resist healing, such as those resulting from some types of cancer radiation treatment or from complications of diabetes.

23 Jul 2020

Mouse orthotopic model was used to determine personalized therapy for relapse sarcoma

A team from IDIBELL and ICO, using a mouse orthotopic model, conducted a real-time personalized oncology study to test the best therapeutic option to treat a type of relapse sarcoma. Malignant Peripheral Nerve Sheath Tumor are very aggressive and do not usually have a good prognosis, especially if complete surgical excision cannot be achieved.

23 Jul 2020

Combining two immunotherapies into a single treatment found to be more effective

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer. But immunotherapies don't work in all patients, and researchers have been searching for ways to increase their effectiveness.

23 Jul 2020

ASCRS releases updated recommendations for surgery in patients with Crohn's disease

Although rates of surgery for Crohn's disease have decreased over the years, many patients still require surgical treatment - due to inadequate responses to medical therapy, severe attacks of acute colitis, and many other situations.

23 Jul 2020

Hollings Cancer Center researcher receives NCI grants for cancer immunotherapy studies

Hollings Cancer Center researcher Jessica Thaxton, Ph.D., is the recipient of two grants totaling $3.4 million from the National Cancer Institute for her work in cancer immunotherapy and cell stress, one of which is part of the Cancer Moonshot Initiative on immunometabolism.

23 Jul 2020

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Scientists have uncovered the genomic signature to explain why 18F-FDG imaging performs better than PSMA-targeted imaging for prostate cancer patients with low or no expression of the prostate-specific membrane antigen (PSMA).

23 Jul 2020

Therapy News and Research

New review provides an update on management of premenopausal osteoporosis

Two-step targeting strategy can increase clinical translation of nanoparticle-based therapies

Study provides new insights into the host cellular response to SARS-CoV-2 infection

Researchers identify TLR7 gene that predisposes elderly patients to severe COVID-19

GlobalData: COVID-19 has pushed infectious disease drugs to top therapy area for CSAs

New study helps identify patients at higher risk of statin-related myopathy

First CAR T-cell therapy for mantle cell lymphoma receives FDA approval

Patients with frailty, older age and UTIs have higher risk of developing sepsis

Bacteriophages may play a key role in treating prosthetic joint infections

UB study validates a novel pharmacological target for Alzheimer’s disease

SphingoTec launches point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction

New model may explain why certain cancer cells are resistant to therapy

Novel research determines the prevalence of chronic kidney disease

Modulating immunometabolic processes to control lung infection

New study seeks to improve treatment options for severe brain injuries

Mouse orthotopic model was used to determine personalized therapy for relapse sarcoma

Combining two immunotherapies into a single treatment found to be more effective

ASCRS releases updated recommendations for surgery in patients with Crohn's disease

Hollings Cancer Center researcher receives NCI grants for cancer immunotherapy studies

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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