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Weak immune status, and not HIV infection affects cavity prevalence in children

Recent studies indicate HIV infection heightens the risk of dental cavities - but a Rutgers researcher has found evidence that the risk of cavities comes not from HIV itself but from a weakened immune system, which could be caused by other diseases.

16 Jul 2020

Overall mortality of COVID-19 patients admitted in ICUs has reduced considerably, shows study

A systematic review and meta-analysis of published studies from three continents shows overall mortality of COVID-19 patients in intensive care units (ICUs) has fallen from almost 60 per cent at the end of March to 42 per cent at the end of May — a relative decrease of one third.

16 Jul 2020

Selective statins may reduce SARS-CoV-2 cell entry and inhibit infection

Statins are a class of drugs often used to control high cholesterol levels in obesity. Now, a study published on the preprint server medRxiv* in July 2020 suggests that statins do not aggravate the risk of COVID-19 infection and may have a small beneficial effect in some cases.

16 Jul 2020

Lung cancer study highlights important factors for treating genomically complicated cancers

A pioneering lung cancer study, led by the University of Birmingham's Cancer Research UK Clinical Trials Unit, has highlighted important factors that will need to be considered in the next wave of precision medicine studies particularly in treating genomically complicated cancers.

16 Jul 2020

Children with MIS-C have different antibody responses than adults with COVID-19

A new study published on the preprint medRxiv in July 2020 reveals that children with the condition Multisystem Inflammatory Syndrome in Children (MIS-C) have a distinctly different pattern of antibody generation compared to adults with COVID-19 disease.

16 Jul 2020

Study identifies factors associated with death in critically ill COVID-19 patients

More than 3 million people in the United States have been infected with COVID-19 and more than 130,000 have died. More people have died of COVID-19 in the U.S. than in any other country, but few studies offer national data on the factors that may contribute to outcomes for critically ill patients.

15 Jul 2020

Dopamine therapy improves cognitive function in patients with mild-to-moderate Alzheimer's

A study supported by the Alzheimer's Drug Discovery Foundation and published today in JAMA Network Open provides the first evidence that rotigotine, a drug that acts on dopamine transmission in the brain, improves cognitive function in patients with mild-to-moderate Alzheimer's disease.

15 Jul 2020

New test uses a single drop of blood to rapidly detect radiation sickness

A new proof-of-concept study reports evidence that a new testing method has the potential to rapidly identify radiation sickness based on biomarkers measured through a single drop of blood.

15 Jul 2020

Promising new CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of the cancer cells.

15 Jul 2020

Hyperbaric oxygen therapy can enhance the cognitive performance of healthy older adults

The Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center, together with the Sackler School of Medicine and Sagol School of Neuroscience at Tel Aviv University, announced today that a peer-reviewed study has demonstrated for the first time that hyperbaric oxygen therapy (HBOT) can significantly enhance the cognitive performance of healthy older adults.

15 Jul 2020

Study identifies possible factors to predict severe toxicities in CAR T patients

Chimeric antigen receptor T-cell therapy (CAR T) has proved to be a valuable treatment option for patients with lymphoma who have failed other therapies. In clinical trials, the cellular immunotherapy was shown to provide durable remissions for nearly 40% of large B cell lymphoma patients.

15 Jul 2020

Anaplastic large cell lymphoma: Defense mechanism against certain drugs promotes cancer growth

A general problem encountered in cancer therapy is that many patients develop resistance to a drug over the course of treatment.

15 Jul 2020

Llama nanobodies block SARS-CoV-2 infection in vitro

Now, a team of scientists at the United Kingdom's Rosalind Franklin Institute may have a surprising solution for the coronavirus pandemic, which has killed more than 574,000 people worldwide.

14 Jul 2020

Human lungs rejected for transplant can be recovered using cross-circulation with pigs

A new experiment by researchers at the Columbia Engineering and Vanderbilt University may have the solution to this long-standing problem. The team revived and repaired the damaged lungs by cross-circulation support of the whole lungs outside the body using the circulatory system with that of a living pig.

14 Jul 2020

Research offers new hope for kidney revival prior to transplantation

New research has demonstrated that kidneys can be revived prior to transplantation by delivering a cell therapy directly to the organ.

14 Jul 2020

MD Anderson and Sanofi collaborate to accelerate development of innovative cancer therapies

The University of Texas MD Anderson Cancer Center and Sanofi today announced a five-year strategic collaboration to accelerate the development of investigational treatments, including targeted and immune therapies, for patients with cancer.

14 Jul 2020

Researchers characterize how changes in glioblastoma cells influence different drug effects

Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways.

14 Jul 2020

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Two new studies led by Renuka Iyer, MD, Section Chief for Gastrointestinal Oncology at Roswell Park Comprehensive Cancer Center, highlight possible new treatment options for patients with neuroendocrine tumors (NETs) - a rare and hard-to-treat cancer.

14 Jul 2020

Dual inhibitor therapy may be safer for CLL patients, Moffitt study shows

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

14 Jul 2020

New reliable method for treating male sterility

Infertility affects one in seven men of reproductive age worldwide. One idea for treating male sterility is spermatogonial stem cell (SSC) therapy.

14 Jul 2020

Therapy News and Research

Weak immune status, and not HIV infection affects cavity prevalence in children

Overall mortality of COVID-19 patients admitted in ICUs has reduced considerably, shows study

Selective statins may reduce SARS-CoV-2 cell entry and inhibit infection

Lung cancer study highlights important factors for treating genomically complicated cancers

Children with MIS-C have different antibody responses than adults with COVID-19

Study identifies factors associated with death in critically ill COVID-19 patients

Dopamine therapy improves cognitive function in patients with mild-to-moderate Alzheimer's

New test uses a single drop of blood to rapidly detect radiation sickness

Promising new CAR T cell therapy results in exceptional patient recovery

Hyperbaric oxygen therapy can enhance the cognitive performance of healthy older adults

Study identifies possible factors to predict severe toxicities in CAR T patients

Anaplastic large cell lymphoma: Defense mechanism against certain drugs promotes cancer growth

Llama nanobodies block SARS-CoV-2 infection in vitro

Human lungs rejected for transplant can be recovered using cross-circulation with pigs

Research offers new hope for kidney revival prior to transplantation

MD Anderson and Sanofi collaborate to accelerate development of innovative cancer therapies

Researchers characterize how changes in glioblastoma cells influence different drug effects

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Dual inhibitor therapy may be safer for CLL patients, Moffitt study shows

New reliable method for treating male sterility

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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