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Using Qigong to manage COVID-19 in older adults

A recent study published in The American Journal of Geriatric Psychiatry in May 2020 reports on the possible usefulness of the integrative practice called Qigong to prevent and manage COVID-19 in older adults.

25 May 2020

Capillary leakage important in COVID-19 respiratory distress

Now, a new study published on the preprint server medRxiv reports the pivotal role played by protein leakage through lung capillaries and promotes the use of serum albumin as a biomarker of disease progression and severity.

24 May 2020

Understanding mechanism behind antibiotic-resistant gonorrhea sets stage for new treatments

Due to the spread of antibiotic-resistant strains of Neisseria gonorrhoeae, existing treatments for gonorrhea, the sexually transmitted infection caused by the bacterium, are no longer effective. In the absence of a vaccine, there is an urgent need to develop novel treatment options.

22 May 2020

Treatment with chloroquine or hydroxychloroquine offers no benefit for COVID-19 patients

A large observational study suggests that treatment with the antimalarial drug chloroquine or its analog hydroxychloroquine (taken with or without the antibiotics azithromycin or clarithromycin) offers no benefit for patients with COVID-19.

22 May 2020

Women and older adults still vastly underrepresented in cholesterol drug trials

Although heart disease is the leading cause of death in women, and older adults are more likely to have heart and vascular disease than young people, randomized clinical trials testing medications to lower cholesterol have historically underenrolled both groups.

22 May 2020

Study uncovers the role of DNA repair in preserving egg quality

A Monash University study has uncovered the role DNA repair plays in preserving egg quality, offering hope for women whose eggs may be damaged through treatments such as radiation and chemotherapy.

22 May 2020

Scientists identify key cell signaling pathway that drives muscle loss

Researchers at the University of Nebraska Medical Center have identified a key cell signaling pathway that drives the devastating muscle loss, or cachexia, suffered by many cancer patients.

22 May 2020

Study reveals mechanism involved in the development of diabetes, fatty liver

A research group including Professor OGAWA Wataru (Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine) and Project Associate Professor HOSOOKA Tetsuya (Division of Development of Advanced Therapy for Metabolic Disease, Kobe University Graduate School of Medicine) has clarified the mechanism underlying the development of diabetes and non-alcoholic steatohepatitis (NASH), a severe form of fatty liver.

22 May 2020

Americans' confidence in medical scientists has grown since the coronavirus outbreak

Americans' confidence in medical scientists has grown since the coronavirus outbreak first began to upend life in the United States, as have perceptions that medical doctors hold very high ethical standards, according to a new Pew Research Center report.

22 May 2020

New clinical trial to test treatment that targets overactive immune response to COVID-19

For some COVID-19 patients, the body's immune response may be as destructive as the virus that causes the disease.

22 May 2020

GlobalData: Patients treated for ICU delirium will increase as COVID-19 outbreak continues

An estimated 70–80% of ventilated patients will experience ICU delirium, which causes patients to enter a confused state and can lead to long-term cognitive impairments and memory deficits. GlobalData, therefore, expects to see an increase in the administration of pharmacological treatments for ICU delirium as the COVID-19 outbreak continues.

22 May 2020

Scientists identify compounds in noxious weed that reduce virulence of Staphylococcus bacteria

Scientists have identified specific compounds from the Brazilian Peppertree -- a weedy, invasive shrub in Florida -- that reduce the virulence of antibiotic-resistant staph bacteria.

22 May 2020

Hydrocarbon bonds may help synthesize large range of novel organic molecules

The most common chemical bond in the living world -- that between carbon and hydrogen -- has long resisted attempts by chemists to crack it open, thwarting efforts to add new bells and whistles to old carbon-based molecules.

22 May 2020

Genetic discoveries show promise for developing new treatment targets for schizophrenia

In recent years, genome-wide association studies (GWAS) have identified many different genetic variants associated with schizophrenia.

22 May 2020

IL-6 blocker use in severe COVID-19 increases risk of secondary infections

With many hundreds of thousands of deaths due to the current COVID-19 pandemic, there is a rush to find an effective vaccine or drug against the virus. A new study on the preprint server medRxiv* in May 2020 shows that the use of some biologically plausible drugs may be counterproductive, and care should be taken when trying out unproven therapies.

22 May 2020

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

As the world struggles to overcome the current COVID-19 pandemic with non-pharmacological interventions, in the absence of an effective drug or vaccine, existing immunomodulators are being repurposed. A new study published on the preprint server medRxiv* in May 2020 shows no clinical benefit to the use of one such drug, called interferon beta 1b (IFN beta1b).

22 May 2020

Preparing to meet SARS-CoV-2 head-on with a panel of neutralizing antibodies

A new study published on the preprint server bioRxiv in May 2020 describes a panel of neutralizing antibodies that bind to multiple attachment sites on the spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the current COVID-19 disease pandemic.

22 May 2020

Simple molecular 'switch' transforms autoimmunity drugs into powerful anti-cancer treatments

Scientists from the Antibody and Vaccine group at the University of Southampton have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular "switch".

21 May 2020

RAAS inhibitors are safe to use in COVID-19 patients, study shows

The coronavirus disease (COVID-19) is a novel illness that has spread across the globe in just five months. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the viral infection binds to the angiotensin-converting enzyme 2 (ACE2) to enter and invade cells.

21 May 2020

New metal-free methodology for fluorination of aliphatic hydrocarbon bonds

Researchers from the Muñiz group have published a paper in Angewandte Chemie - International Edition presenting a new metal-free methodology for the photo-catalyzed nucleophilic fluorination of aliphatic hydrocarbon bonds.

21 May 2020

Drugs News and Research

Using Qigong to manage COVID-19 in older adults

Capillary leakage important in COVID-19 respiratory distress

Understanding mechanism behind antibiotic-resistant gonorrhea sets stage for new treatments

Treatment with chloroquine or hydroxychloroquine offers no benefit for COVID-19 patients

Women and older adults still vastly underrepresented in cholesterol drug trials

Study uncovers the role of DNA repair in preserving egg quality

Scientists identify key cell signaling pathway that drives muscle loss

Study reveals mechanism involved in the development of diabetes, fatty liver

Americans' confidence in medical scientists has grown since the coronavirus outbreak

New clinical trial to test treatment that targets overactive immune response to COVID-19

GlobalData: Patients treated for ICU delirium will increase as COVID-19 outbreak continues

Scientists identify compounds in noxious weed that reduce virulence of Staphylococcus bacteria

Hydrocarbon bonds may help synthesize large range of novel organic molecules

Genetic discoveries show promise for developing new treatment targets for schizophrenia

IL-6 blocker use in severe COVID-19 increases risk of secondary infections

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

Preparing to meet SARS-CoV-2 head-on with a panel of neutralizing antibodies

Simple molecular 'switch' transforms autoimmunity drugs into powerful anti-cancer treatments

RAAS inhibitors are safe to use in COVID-19 patients, study shows

New metal-free methodology for fluorination of aliphatic hydrocarbon bonds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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