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How drug companies covertly promote off-label drug use

Off-label prescription of a drug is generally legal, but promotion of off-label uses by a drug manufacturer is illegal. In an article in this week's PLoS Medicine, two physician researchers describe the techniques that drug companies use to covertly promote off-label use, even when such promotion is illegal.

28 Oct 2008

Scientists discover a catalytic antibody that degrades a known appetite stimulant

The antibody works against the gastric hormone ghrelin (pronounced "grell-in"), which has been linked to weight gain and fat storage through its metabolic actions. These findings point towards a potentially novel treatment for obesity that would interfere directly with the some of the biological mechanisms determining weight.

28 Oct 2008

Lots of neighborhood greenness linked to lower children's body mass

In the first study to look at the effect of neighborhood greenness on inner city children's weight over time, researchers from the Indiana University School of Medicine, Indiana University-Purdue University Indianapolis and the University of Washington report that higher neighborhood greenness is associated with slower increases in children's body mass over a two year period, regardless of residential density.

28 Oct 2008

Improved communication about medications reduces complications among patients using common blood thinner

Patients who report receiving written and verbal instructions on the proper way to take the blood thinner warfarin are significantly less likely to suffer the serious gastrointestinal and brain bleeding problems that are associated with misuse of the drug, according to new research from the University of Pennsylvania School of Medicine.

27 Oct 2008

Lack of brain NMDA receptors linked to schizophrenia

A lack of specific brain receptors has been linked with schizophrenia in new research by scientists at Newcastle University.

27 Oct 2008

Discovery of new gene responsible for puberty disorders

A new gene responsible for some puberty disorders has been identified by Medical College of Georgia researchers.

27 Oct 2008

In mice, anxiety is linked to immune system

In the first study ever to genetically link the immune system to normal behavior, scientists at Rockefeller and Columbia universities show that mast cells, known as the pharmacologic bombshells of the immune system, directly influence how mice respond to stressful situations.

27 Oct 2008

A new role for a critical DNA repair molecule in the immune system

The human immune system is a brilliantly adaptable weapon against foreign invaders. But it all depends on the work of specialized cells called lymphocytes that have made a risky evolutionary gambit to mutate their own DNA.

26 Oct 2008

Breastfeeding and breast sagging, shape

Findings from a study published in the September/October 2008 issue of the Aesthetic Surgery Journal show that, contrary to popular belief, breastfeeding is not a likely cause of post-pregnancy drooping of the breasts.

23 Oct 2008

Why some people have a better head for languages

Learning a second language is usually difficult and often when we speak it we cannot disguise our origin or accent. However, there are important differences between individuals with regard to the degree to which a second language is mastered, even for people who have lived in a bilingual environment since childhood.

23 Oct 2008

Socioeconomic and treatment factors affect non-Hodgkin lymphoma patients' survival

Socioeconomic factors and the type of treatment received have an impact on a non-Hodgkin lymphoma (NHL) patient's risk of dying. That is the finding of a new study published in the December 1, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society.

23 Oct 2008

Sudden cardiac death number one risk for patients on dialysis

In a 10-year study of more than a thousand kidney failure patients, sudden cardiac death emerged as the number one cause of death for patients on dialysis, according to a Johns Hopkins researcher. The study, already published online and appearing in the Nov. 2 issue of Kidney International, identified systemic inflammatory response and malnutrition as key risk factors for the fatal heart attacks.

22 Oct 2008

Worries over test for mad cow disease

A new test to screen blood for the incurable human form of mad cow disease could be available within 18 months, but it has raised concerns.

21 Oct 2008

Johns Hopkins researchers detect sweet cacophany while listening to cellular cross-talk

Johns Hopkins scientists were dubious in the early 1980s when they stumbled on small sugar molecules lurking in the centers of cells; not only were they not supposed to be there, but they certainly weren't supposed to be repeatedly attaching to and detaching from proteins, effectively switching them on and off.

20 Oct 2008

Hand, foot and mouth disease in China kills 3 children and sickens over 100 others

In the latest health scare in China three children have died from hand, foot and mouth disease and another 110 are sick - this is China's second outbreak of the virus this year in young children.

20 Oct 2008

New U.S. infant mortality data released

The United States ranked 29th in the world in infant mortality in 2004, compared to 27th in 2000, 23rd in 1990 and 12th in 1960, according to a new report from CDC's National Center for Health Statistics.

15 Oct 2008

Alcohol linked to brain shrinkage

According to the latest research drinking alcohol shrinks the brain and the more alcohol an individual drinks, the smaller his or her total brain volume will be.

15 Oct 2008

Respiratory sinus arrhythmia is a significant predictor of insomnia in women with breast cancer

A study in the October 15 issue of the Journal of Clinical Sleep Medicine shows that respiratory sinus arrhythmia (RSA) is a significant predictor of insomnia in women with breast cancer and confirmed that longer nocturnal wake episodes were associated with a flatter diurnal cortisol slope.

15 Oct 2008

Nicotine linked to breast cancer growth and spread

A study published in Cancer Research, a journal of the American Association for Cancer Research, suggests a possible role for nicotine in breast tumor development and metastases.

15 Oct 2008

Altruistic behaviour can be sexually attractive to others

Displays of altruism or selflessness towards others can be sexually attractive in a mate. This is one of the findings of a study carried out by biologists and a psychologist at The University of Nottingham.

14 Oct 2008