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Using photoacoustic imaging to visualize scarring in donor kidneys before transplant

When kidney transplants first came into practice in the 1950s, patients with chronic kidney disease could finally picture freedom from the unrelenting routine of blood-cleansing dialysis treatments. Just over a half-century later, demand has completely outstripped supply.

2 May 2020

New study could improve our understanding about platelets

University of Kentucky College of Medicine researcher Sidney Whiteheart has been awarded a prestigious Outstanding Investigator Award from the National Heart, Blood and Lung Institute for his research on how platelets function in hemostasis and during immune responses.

29 Apr 2020

Early Heparin therapy improves hypoxia in COVID-19 patients

The systemic use of heparin for treating severe coronavirus disease (COVID-19) showed significant improvements in oxygen exchange and overall clinical presentation of patients, as reported by a study from Brazil available on a preprint server medRxiv.

26 Apr 2020

Aspirin associated with reduction in risk of several digestive tract cancers

Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers.

15 Apr 2020

Women born by cesarean have greater risk of obesity and diabetes

A new study published in the open-access journal JAMA Network Open in April 2020 suggests that women born by way of a Cesarean section are at higher risk of developing obesity as well as type 2 diabetes mellitus in adult life.

13 Apr 2020

Newer therapies may benefit patients with type 2 diabetes and coronary artery disease

Type 2 diabetes affects treatment options for patients who have both coronary artery disease and T2D, according to a new American Heart Association Scientific Statement, published today in the Association's flagship journal Circulation.

13 Apr 2020

People with type 2 diabetes and heart disease may benefit from newer therapies

Type 2 diabetes (T2D) may affect treatment options for patients who have both coronary artery disease (CAD) and T2D.

13 Apr 2020

Microneedle patches for potential COVID-19 vaccines or therapeutics

The COVID-19 pandemic is spreading over the world, causing panic and illness on a scale unprecedented in one hundred years. Even while the death toll nears 100,000, with over 1.5 million confirmed cases worldwide, public health experts and medical professionals are battling it using all the weapons available. Unfortunately, these are all too few.

9 Apr 2020

Natural approaches along with current therapies could improve colon cancer treatment

Using a modified natural substance along with current approaches could improve colon cancer treatment, according to findings by University of California, Irvine biologists.

6 Apr 2020

Excess cardiac myosin worsens damage to heart tissue during a heart attack

A prevalent heart protein known as cardiac myosin, which is released into the body when a person suffers a heart attack, can cause blood to thicken or clot--worsening damage to heart tissue, a new study shows.

2 Apr 2020

Her genetic test revealed a microscopic problem — and a jumbo price tag

Michelle Kuppersmith, 32, feels great, works full time and exercises three to four times a week. So she was surprised when a routine blood test found that her body was making too many platelets, which help control bleeding.

31 Mar 2020

Ticagrelor therapy, without aspirin, can benefit patients with acute coronary syndrome

Patients with acute coronary syndrome (ACS) who stopped taking aspirin three months after the insertion of a coronary stent and then took the anti-platelet medication ticagrelor alone for nine months had fewer episodes of bleeding and no increase in heart attacks, stroke or other adverse events caused by blockages in the arteries, compared with patients who took both aspirin and ticagrelor for a year.

31 Mar 2020

Clopidogrel added to aspirin and rvaroxaban shows no additional benefit for peripheral artery disease

The results of VOYAGER PAD found that people with peripheral artery disease (PAD) who took the blood thinner rivaroxaban with aspirin after undergoing lower extremity revascularization--a procedure to treat blocked arteries in the leg--had a significant reduction in the risk of major adverse limb and cardiovascular events when compared with those receiving aspirin alone.

31 Mar 2020

Higher serum EPA levels from prescription fish oil associated with lower cardiovascular events

Higher levels of the omega-3 fatty acid eicosapentaenoic acid (EPA) found in the blood—and not a decrease in triglyceride levels as originally thought—appear to explain the striking reductions in cardiovascular events and deaths seen among people taking 4 grams daily of the prescription fish oil, icosapent ethyl, according to findings from a REDUCE-IT substudy presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology

30 Mar 2020

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following percutaneous coronary intervention (PCI) did not meet its stated goal for cutting in half the incidence of serious adverse cardiovascular events, such as heart attack and stroke, in the year following the procedure.

30 Mar 2020

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Results from two subgroup analyses of the Phase IV independent TWILIGHT trial funded by AstraZeneca showed Brilinta (ticagrelor) monotherapy reduced the risk of clinically relevant bleeding over 12 months compared to aspirin plus Brilinta in high-risk coronary patients.

From AstraZeneca 30 Mar 2020

Direct oral anticoagulant more effective in lowering risk of VTE after common orthopedic surgeries

The direct oral anticoagulant rivaroxaban dramatically cut the likelihood of serious venous thromboembolism (VTE) in people recovering from lower limb orthopedic surgery requiring immobilization in comparison with enoxaparin, another anticoagulant agent, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Oral apixaban as effective as dalteparin for treating blood clots in people with cancer

For people with cancer, the oral blood thinner apixaban is at least as effective as dalteparin, a low molecular weight heparin given by injection, in preventing a repeat venous thromboembolism (VTE), or blood clot, with no excess in major bleeding events, according to Phase 3 trial results presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Taking ticagrelor alone better for patients with complex heart disease

Patients with complex heart disease who stopped taking aspirin three months after the insertion of one or more coronary stents and then took the anti-platelet medication ticagrelor alone for a year had fewer episodes of bleeding and no increase in heart attacks, stroke or other adverse events caused by blockages in the arteries, compared with patients who took both aspirin and ticagrelor over the same period.

30 Mar 2020

Trial confirms the effectiveness of TAVR strategy in a real-world setting

Patients who underwent transcatheter aortic valve replacement (TAVR) did not have a higher rate of death at one year compared with those who had their heart valve replaced via open-heart surgery, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Bleeding News and Research

Using photoacoustic imaging to visualize scarring in donor kidneys before transplant

New study could improve our understanding about platelets

Early Heparin therapy improves hypoxia in COVID-19 patients

Aspirin associated with reduction in risk of several digestive tract cancers

Women born by cesarean have greater risk of obesity and diabetes

Newer therapies may benefit patients with type 2 diabetes and coronary artery disease

People with type 2 diabetes and heart disease may benefit from newer therapies

Microneedle patches for potential COVID-19 vaccines or therapeutics

Natural approaches along with current therapies could improve colon cancer treatment

Excess cardiac myosin worsens damage to heart tissue during a heart attack

Her genetic test revealed a microscopic problem — and a jumbo price tag

Ticagrelor therapy, without aspirin, can benefit patients with acute coronary syndrome

Clopidogrel added to aspirin and rvaroxaban shows no additional benefit for peripheral artery disease

Higher serum EPA levels from prescription fish oil associated with lower cardiovascular events

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Direct oral anticoagulant more effective in lowering risk of VTE after common orthopedic surgeries

Oral apixaban as effective as dalteparin for treating blood clots in people with cancer

Taking ticagrelor alone better for patients with complex heart disease

Trial confirms the effectiveness of TAVR strategy in a real-world setting

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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