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New genetic risk report reveals hidden heart disease risk before symptoms appear

Researchers developed and externally validated integrated polygenic risk scores for eight cardiovascular conditions using large U.S.-based biobank data. The clinically orderable report may help identify inherited cardiovascular risk that traditional clinical markers can miss, although broader prospective validation is still needed.

30 Apr 2026

GLP-1 drugs reduce risk of major adverse cardiovascular events

New research has shown that GLP‑1 weight-loss drugs deliver protection against heart attacks, strokes and premature death over a sustained period of time.

30 Apr 2026

Daily self-moxibustion during chemotherapy found to be feasible and acceptable

Chemotherapy-induced pancytopenia remains a serious challenge in cancer care because falling blood counts can lead to treatment delays and dose reductions, with associated impact on survival, as well as potential infections, fatigue, and lower quality of life.

30 Apr 2026

Meth use accounts for nearly 1 in 6 heart attacks, California study shows

Methamphetamine (meth) use accounted for nearly 15% of heart attacks for a decade in a northern California study, published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

30 Apr 2026

Extracellular vesicles from T cells enhance tumor immune response

Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell Medicine.

30 Apr 2026

New CAR T cell design boosts persistence and reduces toxicity

CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting benefit – often because the infused cells fail to expand or persist.

30 Apr 2026

Study reveals new immune mechanism behind mevalonate kinase deficiency

Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder.

30 Apr 2026

T1GRS model enhances prediction of genetic risk for Type 1 diabetes

In people with Type 1 diabetes (T1D), the immune system shuts down the body's ability to make the hormone insulin, responsible for regulating blood sugar and providing cells with glucose to produce energy.

30 Apr 2026

New screening tool predicts health risks for people living with obesity

A simple tool, developed by researchers at Queen Mary University of London and the Berlin Institute of Health at Charité, could help identify which people living with obesity or overweight are most likely to develop serious obesity-related conditions such as type 2 diabetes and heart disease.

30 Apr 2026

Sickness behavior may be a coordinated whole organism immune strategy

Symptoms such as fatigue, loss of appetite, altered sleep, and social withdrawal are often treated as inconvenient side effects of infection.

30 Apr 2026

Liquid biopsy predicts immune response in high-risk breast cancer patients

Immunotherapy has become a standard of care in treating high-risk, early-stage breast cancers, yet it has had limited success in shrinking tumors.

30 Apr 2026

NIH awards $44 million for landmark study on health challenges in the rural South

The University of Texas at San Antonio (UT San Antonio) has been awarded a five-year, $44 million contract from the National Heart, Lung, and Blood Institute of the National Institutes of Health for a landmark study focused on persistent health challenges in the rural South.

30 Apr 2026

Climate change increases stroke risk through extreme weather and pollution

The World Stroke Organization is warning that climate change poses an escalating threat to brain health, with extreme heat in particular increasing the risk of having a stroke and of patients dying from stroke.

30 Apr 2026

Glucose acts as a metabolic signal for myelin development

Researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have uncovered a surprising link between low brain sugar levels and the development of myelin - the protective coating that allows nerve cells to communicate rapidly and efficiently.

30 Apr 2026

Routine blood tests years before conception may predict pregnancy risks

Small abnormalities in blood sugar, blood lipids and inflammation several years before pregnancy are linked to an increased risk of high blood pressure during pregnancy and pre-eclampsia, according to a new study from Karolinska Institutet published in JAMA Network Open.

30 Apr 2026

Maternal screening could help prevent deadly forms of leukemia

A deadly form of leukemia may be stopped before it ever develops by introducing targeted maternal screening in the United States, according to new research.

30 Apr 2026

AI and CRISPR technologies drive proactive health monitoring

JMIR Publications today featured two new stories in its News and Perspectives section, highlighting a shift toward proactive, tech-integrated health monitoring.

30 Apr 2026

Study suggests birth weight affects kidney resilience in ultramarathon athletes

A new study is raising questions about whether human endurance has biological limits shaped long before adulthood-possibly beginning at birth.

30 Apr 2026

Baby teeth show when metal exposure may affect brain development

The study identifies critical windows of metal exposure via baby teeth, revealing impacts on brain development and behavior in children and adolescents.

30 Apr 2026

From killers to strategists: CAR T cells enter their multifunctional era

A review of 1,801 registered CAR T clinical trials shows that multifunctional designs now account for 533 trials and 33% of new CAR T products submitted for clinical testing in 2025. The field is shifting toward multitargeted, safety-controlled, cytokine-secreting, and checkpoint-modulating CAR T cells, but manufacturing, regulation, and limited clinical outcome data remain key barriers.

30 Apr 2026