Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Future cardiac outcomes can be predicted by cellular repair response to exercise

Future cardiac outcomes can be predicted by signs of cardiac stress that appear in the blood in response to exercise, Emory cardiologists report.

4 Dec 2019

Experimental drug better for repeat kidney cancer patients than FDA-approved equivalent

Kidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression with an experimental drug called tivozanib compared to an alternative approved by the U.S. Food and Drug Administration, according to a City of Hope-led study.

4 Dec 2019

Healthcare heroes can come from unexpected places

Although KJ Upshaw's official job title at Cincinnati Children's is floor tech in Environmental Services, he refers to himself simply as the housekeeper.

4 Dec 2019

Researchers awarded $250,000 grant to study tumor microenvironment in lung cancer

Fueling exploration by investigators who collaborate under a research consortium partnership as recognized by the National Cancer Institute, between Rutgers Cancer Institute of New Jersey and Princeton University, the GO2 Foundation for Lung Cancer has awarded $250,000 toward the identification and development of novel strategies to address treatment resistance in non-small cell lung cancer.

3 Dec 2019

Purification scheme allows collection of elusive blood stem cells from zebrafish

Hematopoietic stem cells are multipotent cells that can develop into every type of blood cell in the body.

2 Dec 2019

Stem cells do help restore heart function – but in a different way

A new study published in the journal Nature shows that stem cells do work well to repair the damaged heart – but in an entirely different manner than was originally supposed. The study shows that stem cells, whether living or dead, when injected into the area of damage in the heart in mice, activate an intense acute inflammation. This triggers the classic wound healing response which finally results in the partial or complete recovery of mechanical function of the injured area.

28 Nov 2019

UCLA scientists discover link between a protein and human blood stem cell self-renewal

UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions.

27 Nov 2019

Researchers develop new strategy for treating the most aggressive type of brain cancer

Researchers from the University of São Paulo in Brazil have developed a strategy for treating the most aggressive type of brain cancer in adults that combines a photoactive molecule and a chemotherapeutic agent - both encapsulated in protein-lipid nanoparticles.

27 Nov 2019

Attacking HIV at the source

A new study published on November 26, 2019, in the journal Cell Reports, details a new discovery that may help avert HIV infection right at the start. The virus is known to take a long time to infect a person, and the scientists say they have found a period during which it can be weakened or killed, in the very first hours after it has entered a host. They call this the window of vulnerability.

26 Nov 2019

Looking for the source: new routes for allergy treatment

A new multinational study has reported a very full account of the B lymphocytes that produce group E antibodies, also called IgE (Immunoglobulin E), that are behind allergic reactions, which are common in up to a third of the world’s population.

26 Nov 2019

New way to thwart HIV infection at early stages

1.7 million. That's how many people are infected with the human immunodeficiency virus (HIV) each year worldwide. 1.7 million people who are condemned to lifelong antiretroviral therapy (ART) or risk developing fatal AIDS . Out of the 37.9 million people living with HIV (PLWH), 22.3 million have access to ART, allowing them to have an almost normal lifespan.

26 Nov 2019

Study about cells producing group E antibodies would help fight against allergies

Researchers of Sechenov University together with their colleagues from Russia and Austria summarized everything known about cells producing group E antibodies

25 Nov 2019

BrainStorm publishes NurOwn ALS Phase 2 randomized clinical trial results in Neurology

BrainStorm Cell Therapeutics Inc., a leader in the development of innovative autologous cellular therapies for highly debilitating neurodegenerative diseases, today announced publication of "NurOwn Phase 2 Randomized Clinical Trial in ALS: Safety, Clinical and BioMarker Results," in the international, peer-reviewed journal Neurology.

20 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

New device separates malignant plasma cells from normal ones

Multiple myeloma is a type of blood cancer in which malignant plasma cells, a type of white blood cell, accumulate in the bone marrow.

19 Nov 2019

New microfluidics device detects malignant multiple myeloma cells in blood

Scientists have developed a microfluidics device that could be used for the detection or monitoring of multiple myeloma.

19 Nov 2019

Rutgers Cancer Institute researchers awarded $2.3 million in American Cancer Society grants

More than $2.3 million in Research Scholar Grants from the American Cancer Society have been awarded to three Rutgers Cancer Institute of New Jersey researchers to examine cell metabolism and tumor formation in forms of breast cancer, lung cancer and leukemia.

19 Nov 2019

Newly discovered cell involved in rheumatoid arthritis could serve as treatment target

Researchers have made a discovery about a class of cells involved in rheumatoid arthritis that could instigate new treatments.

18 Nov 2019

New study aims to optimize brain development in babies with congenital heart disease

An upcoming clinical trial at Children's National Hospital will harness cardiopulmonary bypass as a delivery mechanism for a novel intervention designed to stimulate brain growth and repair in children who undergo cardiac surgery for congenital heart disease.

14 Nov 2019

Research explains why immunotherapy fails against prostate cancer bone metastases

Prostate cancer that spreads to the bone triggers the destruction of bone tissue that, in turn, thwarts the effectiveness of immune checkpoint inhibitors by blocking the development of T cells that are crucial to successful treatment, researchers from The University of Texas MD Anderson Cancer Center report in Cell.

14 Nov 2019

Bone Marrow News and Research

Further Reading

Future cardiac outcomes can be predicted by cellular repair response to exercise

Experimental drug better for repeat kidney cancer patients than FDA-approved equivalent

Healthcare heroes can come from unexpected places

Researchers awarded $250,000 grant to study tumor microenvironment in lung cancer

Purification scheme allows collection of elusive blood stem cells from zebrafish

Stem cells do help restore heart function – but in a different way

UCLA scientists discover link between a protein and human blood stem cell self-renewal

Researchers develop new strategy for treating the most aggressive type of brain cancer

Attacking HIV at the source

Looking for the source: new routes for allergy treatment

New way to thwart HIV infection at early stages

Study about cells producing group E antibodies would help fight against allergies

BrainStorm publishes NurOwn ALS Phase 2 randomized clinical trial results in Neurology

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

New device separates malignant plasma cells from normal ones

New microfluidics device detects malignant multiple myeloma cells in blood

Rutgers Cancer Institute researchers awarded $2.3 million in American Cancer Society grants

Newly discovered cell involved in rheumatoid arthritis could serve as treatment target

New study aims to optimize brain development in babies with congenital heart disease

Research explains why immunotherapy fails against prostate cancer bone metastases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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