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New chemical probe could tag cells for detection by MRI

The need to non-invasively "see" and track cells in living persons is indisputable - a boon to both research and development of future therapies. Emerging treatments using stem cells and immune cells are poised to most benefit from cell tracking, which would visualize their behavior in the body after delivery. Clinicians require such data to speed these cell treatments to patients.

15 Mar 2016

Researchers identify potential drug target in skin for itchy feeling

No matter the trigger -- bug bites, a medication side-effect or an itchy wound -- the urge to scratch can be a real pain. Researchers at the Duke University Medical Center have identified a potential drug target in the skin for that itchy feeling.

14 Mar 2016

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

NASA limits an astronaut's radiation exposures to doses that keep their added risk of fatal cancer below 3 percent. Unfortunately, that ceiling restricts the time an astronaut may spend in space, which in turn restricts the ability to perform longer missions, say a mission to Mars.

14 Mar 2016

Scientists sort out mechanism of Alzheimer's disease development

A group of the Lomonosov Moscow State University scientists, together with their colleagues from the Institute of Molecular Biology, Russian Academy of Sciences and the King's College London, succeeded in sorting out the mechanism of Alzheimer's disease development and possibly distinguished its key trigger.

11 Mar 2016

Secretory capacity of human gut does not decline with age, shows study

A breakthrough in basic research and the first comprehensive study on the secretory activity of the human intestine: over a period of eight years, Dr. Dagmar Krüger of the Department of Human Biology at TU Munich has examined more than 2200 specimens from around 450 patients with bowel disease.

10 Mar 2016

Rutgers' new drug candidate may help fight malaria

Malaria killed about 440,000 people - mostly young children - last year, but a new drug candidate discovered at Rutgers may help fight the long-dreaded disease.

8 Mar 2016

NIH scientists show how neurons in the eye may use math to differentiate moving objects

Our eyes constantly send bits of information about the world around us to our brains where the information is assembled into objects we recognize. Along the way, a series of neurons in the eye uses electrical and chemical signals to relay the information. In a study of mice, National Institutes of Health scientists showed how one type of neuron may do this to distinguish moving objects.

8 Mar 2016

Scientists hoping to use biomimetic gel to mechanically reinforce worn-out cartilage

Aching knees and stiff fingers: osteoarthritis is a widespread joint disease with few treatment options. However, there may finally be some hope: American scientists are hoping to mechanically reinforce worn-out cartilage by incorporating a biomimetic gel

7 Mar 2016

Inhibition of mitochondrial calcium uptake specifically toxic to cancer cells

Inhibiting the transfer of calcium ions into the cell's powerhouse is specifically toxic to cancer cells, according to an article published this week in Cell Reports by researchers from the Perelman School of Medicine at the University of Pennsylvania.

4 Mar 2016

High-salt diet may contribute to liver damage

A sprinkle of salt can bring out the flavor of just about any dish. However, it's well known that too much can lead to high blood pressure, a potentially dangerous condition if left untreated.

24 Feb 2016

New research shows copper can destroy MRSA in touch contamination

New research from the University of Southampton shows that copper can destroy MRSA spread by touching and fingertip contamination of surfaces.

24 Feb 2016

Consuming dried plums can protect from radiation-induced bone loss

Dr. Nancy Turner, a Texas A&M AgriLife Research scientist in College Station, was one of a team of researchers who recently studied different interventions to protect from radiation-induced bone loss.

23 Feb 2016

New approach could open door to more personalized medications for diabetes patients

New research from the University of Copenhagen points to an entirely new approach for designing insulin-based pharmaceuticals. The approach could open the door for more personalized medications with fewer side effects for Type 1 Diabetes patients.

19 Feb 2016

Study provides new insights into Retigabine drug

A study published ahead of print in the The Journal of General Physiology has revealed new insights into Retigabine, a known pharmacological treatment for epilepsy.

19 Feb 2016

IONICON's new PTR-TOF 1000 ultra trace gas analyzer to be presented at Pittcon 2016

Up to 10x more sensitivity thanks to the revolutionary new ION-BOOSTER funnel technology.

From Ionicon Analytik Ges.m.b.H. 19 Feb 2016

CHLA, Thermo Fisher Scientific agree to develop NGS-based panel for pediatric cancer research

Children's Hospital Los Angeles and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research. The assay would be CHLA's first NGS panel designed to target biomarkers associated with childhood cancers.

19 Feb 2016

Combining pain medicine with metal ions could destroy drug-resistant cancer cells

Fighting chemoresistant cancer remains a huge challenge that scientists are tackling from as many angles as they can. One alternative approach involves pairing two groups of compounds -- pain medicine and metal ions -- that have individually shown promise as anti-cancer agents. Scientists report in the ACS journal Inorganic Chemistry that combining the two led to new compounds that could destroy drug-resistant cancer cells and leave most normal cells alone in lab tests.

18 Feb 2016

New optogenetic technology could turn on immune cells to attack melanoma tumors

A new optogenetic technology developed at UMass Medical School, called optogenetic immunomodulation, is capable of turning on immune cells to attack melanoma tumors in mice. Using near-infrared light, UMMS researchers have shown they can selectively activate an immune response by controlling the flow of calcium ions into the cell. This breakthrough could lead to less invasive, and more controlled and selective, immunotherapies for cancer treatment.

17 Feb 2016

Discovery could lead to new leukaemia therapies

Human blood cells have olfactory receptors that respond to Sandalore. This could provide a starting point for new leukaemia therapies, as researchers from Bochum report in in the journal "Cell Death Discovery".

3 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

Ion News and Research

New chemical probe could tag cells for detection by MRI

Researchers identify potential drug target in skin for itchy feeling

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

Scientists sort out mechanism of Alzheimer's disease development

Secretory capacity of human gut does not decline with age, shows study

Rutgers' new drug candidate may help fight malaria

NIH scientists show how neurons in the eye may use math to differentiate moving objects

Scientists hoping to use biomimetic gel to mechanically reinforce worn-out cartilage

Inhibition of mitochondrial calcium uptake specifically toxic to cancer cells

High-salt diet may contribute to liver damage

New research shows copper can destroy MRSA in touch contamination

Consuming dried plums can protect from radiation-induced bone loss

New approach could open door to more personalized medications for diabetes patients

Study provides new insights into Retigabine drug

IONICON's new PTR-TOF 1000 ultra trace gas analyzer to be presented at Pittcon 2016

CHLA, Thermo Fisher Scientific agree to develop NGS-based panel for pediatric cancer research

Combining pain medicine with metal ions could destroy drug-resistant cancer cells

New optogenetic technology could turn on immune cells to attack melanoma tumors

Discovery could lead to new leukaemia therapies

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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