Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Edematous severe acute malnutrition linked to DNA modification

A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level - the chemical tags in DNA that help regulate gene expression - between two clinically distinct forms of acute childhood malnutrition known as edematous severe acute malnutrition (ESAM) and non-edematous SAM (NESAM).

19 Dec 2019

Heavy drinking damages the heart

Drinking too much destroys the liver, as is well known. A new study published in the Journal of the American Heart Association on December 18, 2019, shows that excessive alcohol consumption also damages the heart muscle. This is seen by a rise in the level of certain biological molecules in the blood.

18 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Women who live near green space may be at lower risk of excess weight, obesity

Women who live less than 300 meters from green space may be at lower risk of excess weight or obesity.

17 Dec 2019

Perinatal exposure of rats to flame retardants changes the liver epigenome

Studies have shown that perinatal exposure of rats and mice to common flame retardants found in household items permanently reprograms liver metabolism, often leading later in life to insulin resistance and non-alcoholic fatty liver disease.

13 Dec 2019

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

Efforts to prevent new HIV transmissions in the United States must be accompanied by advances in addressing HIV-associated comorbidities to improve the health of people already living with HIV, National Institutes of Health experts assert in the third of a series of JAMA commentaries.

11 Dec 2019

New research may help guide future treatment for non-alcoholic fatty liver disease

Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron deficiency that simply leaves them too tired to get off the couch.

11 Dec 2019

Study explores cost-effectiveness of transient elastography for detecting liver fibrosis

Non-alcoholic fatty liver diseases (NAFLD) and alcohol-related diseases (ALD) are currently the leading cause of chronic disease, cancer and mortality associated with this organ in developed countries.

10 Dec 2019

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury.

9 Dec 2019

New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Patients with nonalcoholic steatohepatitis, a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change.

6 Dec 2019

Chronic disease prevention could help curb the opioid epidemic

Preventing chronic disease could help curb the opioid epidemic, according to research from the University of Georgia.

5 Dec 2019

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.

5 Dec 2019

Georgia State professor selected as National Academy of Inventors Fellow

Jenny Yang, a Regents' Professor of chemistry at Georgia State University and the associate director of the Center for Diagnostics and Therapeutics, has been selected as a National Academy of Inventors (NAI) Fellow, the academy board announced on Tuesday.

5 Dec 2019

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural changes.

4 Dec 2019

Updated website reflects major developments in identification, management of chronic hepatitis C

A website developed by the American Association for the Study of Liver Diseases and the Infectious Diseases Society of America to provide up-to-date guidance on the management of hepatitis C was recently revised to reflect important developments in the identification and management of chronic hepatitis C (HCV).

4 Dec 2019

Leaky gut and space flight – the mechanism revealed

A new study on the effects of simulated microgravity, the condition that astronauts face in space, interferes with the epithelial barrier of the intestine, and the effect persists even after the astronaut returns to a normal environment. The research is published in the journal Scientific Reports.

28 Nov 2019

Life expectancy in the United States steadily decreasing

Life expectancy in the United States is decreasing, and it may be due to the increasing rates of drug abuse and suicide, a new study finds.

27 Nov 2019

New wearable sensor for non-invasive gout detection

Biomedical scientists are working hard to create more pain-free methods of disease detection and treatment. A simple blood test is highly informative but arouses intense anxiety in many people. Now a new paper published in the journal Nature Biotechnology on November 25, 2019, reports on a new wearable sensor that can be successfully adapted to mass production, is flexible, and can be used to produce readouts of metabolites and nutrients in the blood based on a sweat analysis.

26 Nov 2019

Space travel can affect intestinal function of astronauts

Bacteria, fungi, and viruses can enter our gut through the food we eat. Fortunately, the epithelial cells that line our intestines serve as a robust barrier to prevent these microorganisms from invading the rest of our bodies.

26 Nov 2019

Liver Disease News and Research

Further Reading

Edematous severe acute malnutrition linked to DNA modification

Heavy drinking damages the heart

Using math equations to detect and forecast liver cancer risk

Women who live near green space may be at lower risk of excess weight, obesity

Perinatal exposure of rats to flame retardants changes the liver epigenome

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

New research may help guide future treatment for non-alcoholic fatty liver disease

Study explores cost-effectiveness of transient elastography for detecting liver fibrosis

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

New startup aims to prevent reperfusion-related organ damage after liver transplant

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Chronic disease prevention could help curb the opioid epidemic

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Georgia State professor selected as National Academy of Inventors Fellow

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Updated website reflects major developments in identification, management of chronic hepatitis C

Leaky gut and space flight – the mechanism revealed

Life expectancy in the United States steadily decreasing

New wearable sensor for non-invasive gout detection

Space travel can affect intestinal function of astronauts

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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