Precision Medicine News and Research

RSS

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Researchers develop novel technique to identify relationships among medical concepts

A team of researchers from the Department of Veterans Affairs, Oak Ridge National Laboratory, Harvard's T.H. Chan School of Public Health, Harvard Medical School and Brigham and Women's Hospital has developed a novel, machine learning–based technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.

28 Apr 2022

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

28 Apr 2022

Researchers identify four new target molecules for future personalized MS treatment

Currently available therapies to treat multiple sclerosis (MS) lack precision and can lead to serious side effects.

27 Apr 2022

Blood test could aid in the differential diagnosis of preeclampsia and COVID-19 in pregnant women

Pregnancy brings deep changes in women's physiology, especially regarding her blood system. The placenta is the organ which ensures an efficient communication between the mother and the baby.

27 Apr 2022

Study finds a bidirectional link between gastrointestinal issues and internalized symptoms in kids with autism

Children with autism spectrum disorder tend to experience gastrointestinal issues, such as constipation and stomach pain, at a higher rate than their neurotypical peers.

26 Apr 2022

Clinical traits with inflammation characterization of long COVID and correlation with one-year recovery after COVID-19-linked hospitalization

Researchers presented the clinical traits with inflammation characterization of long COVID and correlation with one-year recovery after COVID-19-linked hospitalization.

26 Apr 2022

Scientists win $2.85 million grant to use novel technology for studying babies with hydrocephalus

A five-year, $2.85 million grant to use novel technology to study babies with hydrocephalus has been awarded to a team of UTHealth Houston researchers by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

25 Apr 2022

New study shows racial differences in breast cancer genomic profiling

A new study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has found that Black women with metastatic breast cancer were less likely to have tumors with treatable genetic variations than white and Asian women.

25 Apr 2022

Study highlights a rapidly increasing patient population with long COVID and lack of treatments

A new UK study of more than 2,000 patients after hospitalization with COVID-19 presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon 23-26), and published in The Lancet Respiratory Medicine shows that, one year after having COVID-19, only around one in four patients feel fully well again.

24 Apr 2022

Miniature replica of the heart could give a more accurate view of how the organ works

There's no safe way to get a close-up view of the human heart as it goes about its work: you can't just pop it out, take a look, then slot it back in.

22 Apr 2022

Blood test can reveal the presence of circulating melanoma cells, research shows

New research in Advanced NanoBiomed Research indicates that testing an individual's blood can reveal the presence of circulating melanoma cells.

20 Apr 2022

What does the Future of Microfluidics within Research Look Like?

We speak to France Hamber, CEO of Fluigent, about their microfluidics solutions and how they are allowing scientists to focus more on the science than the setup.

From Fluigent 11 Apr 2022

MOFs could help improve the delivery of genetic cargo into target cells

Hybrid material helps ferry genetic cargo to target cells. An emerging type of material called a metal-organic framework(MOF) could help improve the delivery of genetic material for treating disease.

10 Apr 2022

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

New findings from the ongoing Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study suggest that certain rheumatoid arthritis drugs may lower incidence of Alzheimer's disease and related dementias in people with cardiovascular disease.

8 Apr 2022

Researchers discover over 40 new genetic markers for Alzheimer’s disease

A new Nature Genetics study describes over 70 gene markers that appear to be significantly associated with AD risk using translational genomics.

6 Apr 2022

Gut bacterium may be an important factor in resistance to antihypertensive medications

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

5 Apr 2022

Human genome sequenced in its entirety for the first time

An international team of almost one hundred scientists has uncovered the complete, gap-free human genome by deciphering the remaining and hitherto unknown sequences – opening the door for novel approaches to treat various diseases. This seminal, historical study is published in the renowned journal Science.

3 Apr 2022

Research illuminates why immune disorders affect only one of two identical twins

Scientists have long queried the causes of immune disorders in only one of two identical twins with identical genes. New research from the Wellcome Sanger Institute, the Josep Carreras Leukaemia Research Institute in Spain and their collaborators, has found the answer lies in both alterations in immune cell-cell communication and the epigenome, the host of biological processes that regulate how our genes function.

1 Apr 2022

3D Printing Testicular Cells to Treat Infertility

In this interview, we speak to Dr. Ryan Flannigan about his latest research that involved the 3D printing of sperm cells to help treat male infertility.

31 Mar 2022