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Healthy glial cell transplants slow Huntington’s disease progression

Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed motor and cognitive decline but also extended lifespan.

17 Jun 2025

Evosep joins P4ML to power world’s largest multi-omic human health study of two million samples

Evosep, a global leader in robust, high-throughput proteomics technologies, has been selected as the proteomics platform provider for the P4ML - OMICAssist Study—the world's largest multi-omic precision medicine initiative, launched by P4ML alongside its strategic academic, health regulatory, and semi-state partners in the United Arab Emirates.

From Evosep 17 Jun 2025

Breakthrough therapy targets aggressive bladder cancer variant

Bladder tumors that have been excluded from clinical trials have a few things in common that could lead to new therapies.

17 Jun 2025

Berries pack more fiber and antioxidants than America’s most-eaten fruits

Replacing one daily serving of commonly eaten fruits like apples or bananas with berries significantly boosts nutrient density in USDA dietary patterns. The modeling analysis showed notable gains in anthocyanins, fiber, and vitamins, with only modest cost increases.

16 Jun 2025

Mitochondrial dysfunction drives cerebellar damage in multiple sclerosis

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement and balance, potentially leading to tremors, poor coordination, and trouble with motor control.

16 Jun 2025

Immune tolerance to gut microbes depends on ancient protein STING

Thousands of bacterial and other microbial species live in the human gut, supporting healthy digestion, immunity, metabolism and other functions.

16 Jun 2025

New hereditary condition impairs DNA repair and raises blood cancer risk

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.

16 Jun 2025

Scientists discover molecule that switches off brown fat activity

Obesity, diabetes and cardiovascular diseases are increasingly present in the population. Brown adipose tissue has a protective function against these prevalent diseases, as it burns calories and can produce body heat from fat.

16 Jun 2025

New computational tool uncovers hidden genetic mutations in proteins

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

16 Jun 2025

Indiana University researcher helps develop FDA-approved Alzheimer’s test

A first-of-its-kind blood test to detect amyloid plaques in the brain associated with Alzheimer's disease recently received clearance from the U.S. Food and Drug Administration. An Indiana University School of Medicine researcher who helped lead the discovery and development of one of the biomarkers the test identifies hopes it will provide greater access and a more accurate diagnosis for patients.

16 Jun 2025

How funding influences cardiac red meat study conclusions

A review reveals how industry funding influences red meat studies, highlighting the need for transparent nutrition research on cardiovascular health impacts.

16 Jun 2025

Tumor collagen structure may help explain racial disparities in cancer outcomes

In cancer care, accurate tools for predicting whether a tumor will spread (metastasize) can help patients receive the most appropriate treatments.

15 Jun 2025

Small antibodies provide broad protection against SARS coronaviruses

Scientists have discovered a unique class of small antibodies that are strongly protective against a wide range of SARS coronaviruses, including SARS-CoV-1 and numerous early and recent SARS-CoV-2 variants.

14 Jun 2025

SREBP identified as a central regulator of lipid metabolism and disease

Announcing a new publication for Acta Materia Medica journal. In addition to regulating lipid biosynthesis and uptake, sterol regulatory element binding protein (SREBP) is involved in mediating biological signaling networks.

14 Jun 2025

RNA steps up to protect the genome from DNA knots

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot.

13 Jun 2025

UK study finds small proportion of early Alzheimer’s patients suitable for latest treatments

Few people in the UK with early stage Alzheimer's disease are likely to be suitable for the latest drugs which aim to halt progress of the condition, yet many are nevertheless likely to be referred for these treatments, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

13 Jun 2025

Mapping genetic activity offers new clues for personalized cancer treatment

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment.

13 Jun 2025