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Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

Swedish HCW study shows COVID booster shots have limited effect on Omicron

Researchers examine emerging infections in healthcare workers who received the booster vaccination either with or without prior SARS-CoV-2 infection.

5 Apr 2022

Does COVID-19 vaccination benefit those with prior SARS-CoV-2 infection?

Researchers evaluate the effectiveness of four COVID-19 vaccines against symptomatic infection, hospitalization, and death in convalescent individuals.

5 Apr 2022

SARS-CoV-2 Omicron breakthrough infections induce antibodies with cross-variant neutralization potential and recall memory B cells

Researchers reported breakthrough infections by SARS-CoV-2’s new variant of concern, Omicron, that elicited broadly cross-reactive neutralizing antibodies in the BNT162b2-vaccinated individuals.

5 Apr 2022

Pre-existing memory B cell dynamics during SARS-CoV-2 Omicron breakthrough infection

A new study analyzed the recall of pre-existent cross-reactive memory B cells upon the SARS-CoV-2 Omicron breakthrough infections.

5 Apr 2022

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

A recent study observed that the replication of the SARS-CoV-2 Omicron variant was restricted in human lung tissues

5 Apr 2022

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

A recent study investigated the impact of a recombinant fragment of cellular glycoprotein Gal-3BP on IL-6 expression in acute COVID-19.

5 Apr 2022

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Researchers profiled cardiac tissue transcriptomes of COVID-19 patients.

5 Apr 2022

Prior COVID vaccination induces a more robust antibody response to Omicron

A recent study posted to the medRxiv* preprint server assessed the impact of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination on the human immune response against SARS-CoV-2 Omicron infection.

5 Apr 2022

Framework for genomic surveillance of SARS-CoV-2 Mpro evolution

A recent study posted to the bioRxiv* preprint server investigated the active genetic evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), its emerging mutations, and the existence of antiviral resistance against Mpro inhibitors like paxlovid.

5 Apr 2022

Air surveillance of SARS-CoV-2 and other respiratory pathogens

A recent study posted to the medRxiv* preprint server reported severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detection in air samples from real-world congregate settings.

4 Apr 2022

BNT162b2 booster vaccine provides equal protection against BA.1 and BA.2

Researchers compare the neutralization of BA.1 and BA.2 strains in immunized people who had received two doses and a booster BNT162b2 mRNA vaccine.

4 Apr 2022

Study suggests severe neuroinvasion by SARS-CoV-2 in individuals with alcohol use disorder

Researchers investigated the effect of repeated alcohol exposure and withdrawal on angiotensin-converting enzyme 2 and transmembrane serine protease 2 expression, putative regulators of SARS-CoV-2 entry, in discrete brain regions.

4 Apr 2022

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

In a recent study published in the journal PLOS Genetics, researchers explored severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) editing in host cells.

4 Apr 2022

mRNA-1273 and BNT162b2 COVID-19 vaccines induce slightly different immune responses

In a recent study published in the journal Science, researchers observed differential effector functions of antibodies elicited by Pfizer’s BNT162b2 and Moderna’s messenger ribonucleic acid (mRNA)-1273 coronavirus disease 2019 (COVID-19) vaccines.

4 Apr 2022

Smart toilets for passive surveillance of SARS-CoV-2

In a recent study published in Nature Digital Medicine, researchers highlighted a potential strategy for using a smart toilet platform, Coronavirus: Integrated Diagnostic (COV-ID), for passive monitoring of coronavirus disease 2019 (COVID-19).

3 Apr 2022

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Scientists develop a formulation for the pulmonary administration of siRNA. The aim was to suppress the replication of SARS-CoV-2.

3 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

Study investigates messenger ribonucleic acid-based SARS-CoV-2 vaccine efficacy against SARS-CoV-2 Omicron in Denmark

A new study assessed the efficacy of two SARS-CoV-2 vaccines against Omicron infections and disease-related hospitalization in the Denmark population.

1 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Ribonucleic Acid News and Research

Phenotypic changes in monocytes from COVID-19 patients

Swedish HCW study shows COVID booster shots have limited effect on Omicron

Does COVID-19 vaccination benefit those with prior SARS-CoV-2 infection?

SARS-CoV-2 Omicron breakthrough infections induce antibodies with cross-variant neutralization potential and recall memory B cells

Pre-existing memory B cell dynamics during SARS-CoV-2 Omicron breakthrough infection

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Prior COVID vaccination induces a more robust antibody response to Omicron

Framework for genomic surveillance of SARS-CoV-2 Mpro evolution

Air surveillance of SARS-CoV-2 and other respiratory pathogens

BNT162b2 booster vaccine provides equal protection against BA.1 and BA.2

Study suggests severe neuroinvasion by SARS-CoV-2 in individuals with alcohol use disorder

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

mRNA-1273 and BNT162b2 COVID-19 vaccines induce slightly different immune responses

Smart toilets for passive surveillance of SARS-CoV-2

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Study investigates messenger ribonucleic acid-based SARS-CoV-2 vaccine efficacy against SARS-CoV-2 Omicron in Denmark

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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