Bone News and Research

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Body mass often down to our genes

Your friend can eat whatever she wants and still fit into her prom dress, but you gain five pounds if you just look at that chocolate cake.

2 Apr 2008

Study shows Actos prevented progression of atherosclerotic plaque volume in patients

New data from a clinical trial using intravascular ultrasound (IVUS) technology found that in patients living with type 2 diabetes, ACTOS (pioglitazone HCl) reduced the atherosclerotic burden in the coronary arteries compared to glimepiride, and prevented progression compared to baseline.

1 Apr 2008

Teenage brains are different

Many parents are convinced that the brains of their teenage offspring are different than those of children and adults.

31 Mar 2008

Stem cells from hair follicles may help 'grow' new blood vessels

For a rich source of stem cells to be engineered into new blood vessels or skin tissue, clinicians may one day look no further than the hair on their patients' heads, according to new research published earlier this month by University at Buffalo engineers.

31 Mar 2008

Keeping in good shape in old age is harder for women

Women aged 65-plus find it harder than men of the same age to preserve muscle - which probably impacts on their ability to stay as strong and fit, according to new research.

28 Mar 2008

Study shows that a larger abdomen in midlife increases risk of dementia

People in their 40s with larger stomachs have a higher risk for dementia when they reach their 70s, according to a study published in the March 26, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology .

28 Mar 2008

Softening of the skull bones in normal-looking babies might reflect vitamin D deficiency during pregnancy

Softening of the skull bones in normal-looking babies might reflect vitamin D deficiency during pregnancy, according to a new study accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM).

26 Mar 2008

U.S. Patent Office confirms validity of Osteotech's U.S. patent on mixtures of a radiolucent material

Osteotech, Inc. ( NASDAQ:OSTE ) , a leader in the emerging field of biologic solutions for regenerative medicine, announced today that the United States Patent and Trademark Office has confirmed the validity of its U.S. Patent No. 5,676,146.

25 Mar 2008

How humans make up for an 'inborn' vitamin C deficiency

A new study appears to explain how humans, along with other higher primates, guinea pigs and fruit bats, get by with what some have called an “inborn metabolic error”: an inability to produce vitamin C from glucose.

24 Mar 2008

Deadly genetic disease prevented before birth in zebrafish with genetic patch

By injecting a customized "genetic patch" into early stage fish embryos, researchers at Washington University School of Medicine in St. Louis were able to correct a genetic mutation so the embryos developed normally.

24 Mar 2008

Are dual cord blood banks the answer to increasing stem cell demand?

In this week's BMJ, two senior doctors, Professors Nicholas Fisk and Rifat Atun, analyse the UK's growing cord blood banking industry and the potential impact of a new bank that provides blood for both personal and public use.

24 Mar 2008

Management of esophageal perforation

Management of ingested foreign bodies is a common clinical encounter.

19 Mar 2008

The effect of melatonin on colitis

In rats with experimental colitis, the marked increase in bacterial translocation in postcolitis rats has been reversed by melatonin administration.

19 Mar 2008

$New way to predict fracturing in statues and bones$

New way to predict fracturing in statues and bones

For statues, stress injuries come from standing in place for hundreds of years.

19 Mar 2008

Survival mechanism of T lymphocytes uncovered

When an individual is challenged by a virus, a bacterium or any other infectious agent, several classes of white blood cells are being activated in order to fight the invasion.

19 Mar 2008

Research leads to innovative therapies against cystic fibrosis

New U of T research holds promise for developing innovative therapies against cystic fibrosis and may also serve as a model for future therapies against the HIV virus.

19 Mar 2008

New interventional radiology treatment shows promise for complications from bone marrow, stem cell tranplants

The standard treatment to treat graft-versus-host disease (GVHD) after bone marrow or cord blood transplant is intravenous (IV) steroids that alter the immune response; however, it is not always effective and failure results in very high mortality.

19 Mar 2008

$Variants of the gene LRP5 associated with increased risk of bone fractures, low bone mineral density$

Variants of the gene LRP5 associated with increased risk of bone fractures, low bone mineral density

Results from a large study indicate that variants of the gene LRP5 are associated with a significant increase in the risk of fractures, by up to 20 percent, and lower levels of bone mineral density in the spine and hip, according to a study in the March 19 issue of JAMA, a theme issue on Genetics and Genomics.

19 Mar 2008

New understanding of rare immune disorder called Job's syndrome

Scientists have made another major breakthrough--the second in the past year--in understanding a rare immune disorder called Job's syndrome.

18 Mar 2008

New treatment for severe frostbite

Using imaging to visualize areas lacking blood flow and deliver drugs via catheter, interventional radiologists are reopening recently frozen, clotted arteries with clot-busting and anti-spasmodic drugs.

18 Mar 2008