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Blocking nuclear pore complex formation can help selectively kill cancer cells

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes--large channels that control the flow of materials in and out of the cell nucleus--shrank aggressive tumors in mice while leaving healthy cells unharmed.

28 Sep 2020

Targeted therapy found to be effective at shrinking tumors in patients with nonsmall-cell lung cancer

An international team of researchers has found that selpercatinib, a drug that precisely targets cancers driven by mutations or alterations in the gene RET, was effective at shrinking tumours in patients with nonsmall cell lung cancer (NSCLC), with a majority of patients living for more than a year without disease progression.

28 Sep 2020

Early introduction of gluten may be an effective celiac disease prevention strategy

Introducing high doses of gluten from four months of age into infants' diets could prevent them from developing celiac disease, a study has found.

28 Sep 2020

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

The National Comprehensive Cancer Network today announced the publication of new NCCN Clinical Practice Guidelines in Oncology for Pediatric Hodgkin Lymphoma. Hodgkin lymphoma is one of the most curable forms of pediatric cancer, with long-term survival rates of 90% or higher.

28 Sep 2020

Innovative nature-based solutions to reduce urban air pollution

It is estimated that air pollution causes around 800 000 premature deaths every year in the EU alone, and the majority of us, especially those living in cities, are regularly exposed to air containing high levels of pollutants.

28 Sep 2020

Complex SARS-CoV-2 serology means universal immunological assay is not feasible

As we improve our understanding of immune responses and correlates of protection against the severe acute respiratory syndrome coronavirus (SARS-CoV-2), two UK researchers emphasize that we will probably utilize different assays to tackle specific questions. Their commentary is published in the prestigious journal Lancet Infectious Diseases.

27 Sep 2020

ECMO appears to be saving the lives of many critically ill COVID-19 patients

It saved lives in past epidemics of lung-damaging viruses. Now, the life-support option known as ECMO appears to be doing the same for many of the critically ill COVID-19 patients who receive it, according to a new international study.

26 Sep 2020

Researchers gain deep insights into the structure of birds’ brains

Some birds can perform amazing cognitive feats – even though their forebrains seem to just consist of lumps of grey cells, while mammalian forebrains harbour a highly complex neocortex.

26 Sep 2020

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

The stroma of the choroid plexus is one of the locations within the central nervous system (CNS) that serves as a shelter for tumor cells, allowing them to elude chemotherapy and potentially cause subsequent relapses in childhood acute lymphoblastic leukaemia, according to research led by the Complutense University of Madrid.

25 Sep 2020

New drug offers hope for young boys with Duchenne muscular dystrophy

A new drug offers hope for young boys with the progressive neuromuscular disease Duchenne muscular dystrophy (DMD) by potentially offering an alternative to high-dose glucocorticoids that have significant side effects.

25 Sep 2020

New insights on pediatric mental health boarding in emergency departments

A Dartmouth-led study, published in the journal Pediatrics, offers new details about pediatric mental health boarding in emergency departments across the country, a problem that has steadily increased in the last 10 years and been made worse by a shortage of psychiatric resources.

25 Sep 2020

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

University of Minnesota Medical School researchers received funding from the Parsemus Foundation to initiate research on the widely-used diabetes medication, metformin, available globally as an inexpensive generic drug for prevention and treatment for COVID-19.

25 Sep 2020

FDA approves first drug for patients with hypereosinophilic syndrome in nearly 14 years

Today, the U.S. Food and Drug Administration approved Nucala (mepolizumab) for adults and children aged 12 years and older with hypereosinophilic syndrome (HES) for six months or longer without another identifiable non-blood related cause of the disease.

25 Sep 2020

Women treated with fertility-sparing surgery for ovarian tumors could become pregnant

Women receiving fertility-sparing surgery for treatment of borderline ovarian tumors were able to have children, a study from Karolinska Institutet in Sweden published in Fertility & Sterility shows.

25 Sep 2020

Study identifies potential drug target for dangerous E. coli infections

Escherichia coli, known as E. coli, are bacteria which many people associate with causing mild food poisoning, but some types of E. coli can be fatal.

25 Sep 2020

Low levels of prenatal alcohol consumption can affect child's brain development

New research from the University of Sydney finds that even low levels of alcohol consumption during pregnancy can have an impact on a child's brain development and is associated with greater psychological and behavioral problems in youth including anxiety, depression and poor attention.

25 Sep 2020

Patients with severe COVID-19 have antibodies blocking body's important defense mechanisms

Persons with critical corona-disease may have antibodies blocking the body´s most important defence mechanisms.

25 Sep 2020

Brain imaging analyses can reveal wounds of childhood trauma

Being traumatized can cause what are known as dissociative symptoms--such as experiencing amnesia, an out-of-body experience, feeling emotionally numb--which may help people cope. Experiencing these symptoms intensely or for a long time, however, can negatively impact an individual's ability to function.

25 Sep 2020

Conflict, climate instability, and COVID-19 are affecting the health of women and children

Fragile gains made to advance women and children's health are threatened by conflict, the climate crisis and COVID-19, according to a new report from Every Woman Every Child.

25 Sep 2020

FDA issues updated recommendations concerning dental amalgam

Part of our role in protecting patients is to regularly evaluate, monitor and update scientific evidence on the risks from medical devices—including issues related to the materials used in devices, such as metals.

25 Sep 2020

Children News and Research

Blocking nuclear pore complex formation can help selectively kill cancer cells

Targeted therapy found to be effective at shrinking tumors in patients with nonsmall-cell lung cancer

Early introduction of gluten may be an effective celiac disease prevention strategy

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

Innovative nature-based solutions to reduce urban air pollution

Complex SARS-CoV-2 serology means universal immunological assay is not feasible

ECMO appears to be saving the lives of many critically ill COVID-19 patients

Researchers gain deep insights into the structure of birds’ brains

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

New drug offers hope for young boys with Duchenne muscular dystrophy

New insights on pediatric mental health boarding in emergency departments

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

FDA approves first drug for patients with hypereosinophilic syndrome in nearly 14 years

Women treated with fertility-sparing surgery for ovarian tumors could become pregnant

Study identifies potential drug target for dangerous E. coli infections

Low levels of prenatal alcohol consumption can affect child's brain development

Patients with severe COVID-19 have antibodies blocking body's important defense mechanisms

Brain imaging analyses can reveal wounds of childhood trauma

Conflict, climate instability, and COVID-19 are affecting the health of women and children

FDA issues updated recommendations concerning dental amalgam

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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