Infectious Diseases News and Research

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How do infections and toxins launch a cell's self-destruct and alarm system?

Cells are coded with several programs for self-destruction.

11 Mar 2008

Tackling antimicrobial resistance

Drug resistance is making many diseases increasingly difficult and sometimes impossible to treat, according to Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

11 Mar 2008

Japanese find way to make flu vaccine effective for multiple strains

Japanese scientists say they are well on the way to developing influenza vaccines which are effective for multiple strains of the disease, including strains of the bird flu virus.

11 Mar 2008

Pandemic influenza could be mitigated if measures were implemented quickly

An outbreak of pandemic influenza in the U.S. could be mitigated with prompt implementation of social-distancing measures combined with antiviral treatment and prophylaxis until a vaccine is available, according to new findings published in the online Early Edition of PNAS.

10 Mar 2008

London School of Hygiene and Tropical Medicine receives new Gates funding to fight disease

The London School of Hygiene & Tropical Medicine (LSHTM) has been awarded grant funding totalling $46.4 million from the Bill and Melinda Gates Foundation (BMGF) and $12.7 million from other partners, to help find new and effective ways of treating and preventing malaria, tuberculosis (TB) and HIV/AIDS.

10 Mar 2008

Research helps explain why some flu strains cause major pandemics and others lead to seasonal epidemics

The exchange of genetic material between two closely related strains of the influenza A virus may have caused the 1947 and 1951 human flu epidemics, according to biologists.

6 Mar 2008

New malaria drug also treats toxoplasmosis

A new drug that will soon enter clinical trials for treatment of malaria also appears to be 10 times more effective than the key medicine in the current gold-standard treatment for toxoplasmosis, a disease caused by a related parasite that infects nearly one-third of all humans—more than two billion people worldwide.

6 Mar 2008

Stark warning about HIV in Australia

A new study has a stark warning about HIV numbers in Australia. According to recent research, if current trends continue, parts of Australia could be facing a surge of HIV infection rates in the next 7 years.

5 Mar 2008

Predicting microbicide use in women

Using a new tool designed to measure a woman's willingness to use a microbicide (topical gels designed to prevent the sexual transmission of HIV), researchers at The Miriam Hospital and Brown University found that women who have used protective methods in the past, and those with casual sexual partners were more willing to use a microbicide compared to their peers.

4 Mar 2008

Potential target to treat deadly bloodstream infections

Researchers at the University of Illinois at Chicago have discovered a possible target to treat bloodstream bacterial infections.

28 Feb 2008

Springer launches 18,000 searchable online protocols in life sciences and biomedicine

Springer Science+Business Media (www.springer.com) has announced the release of Springer Protocols, a protocol database of more than 18,000 searchable online protocols in life sciences and biomedicine.

28 Feb 2008

Discovery of potential drug targets for sepsis

"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with his postdoctoral fellow Frank Niessen.

28 Feb 2008

Scientists devise approach that stops HIV at earliest stage of infection

Their study, which appears this week in the online Early Edition of the Proceedings of the National Academy of Sciences (PNAS), may re-energize attempts to create a preventive/therapeutic vaccine against HIV, say the authors.

28 Feb 2008

Artificial 'cells' that boost the immune response to cancer

Using artificial cell-like particles, Yale biomedical engineers have devised a rapid and efficient way to produce a 45-fold enhancement of T cell activation and expansion, an immune response important for a patient's ability to fight cancer and infectious diseases, according to an advance on line report in Molecular Therapy.

27 Feb 2008

URMC cardiac team celebrates 100th heart transplant

The Program in Heart Failure and Transplantation at the University of Rochester Medical Center has reached a milestone, performing its 100th cardiac transplant surgery.

27 Feb 2008

Nanoemulsion vaccines show increasing promise

A novel technique for vaccinating against a variety of infectious diseases - using an oil-based emulsion placed in the nose, rather than needles - has proved able to produce a strong immune response against smallpox and HIV in two new studies.

27 Feb 2008

Combination vaccine against Ebola and Marburg viruses provides complete protection for monkeys

An experimental, combination vaccine against Ebola and Marburg viruses using virus-like particles (VLPs) provides complete protection against infection in monkeys.

27 Feb 2008

Tenofovir gel safe for daily use over an extended period

A vaginal microbicide that incorporates an antiretroviral (ARV) drug normally used to treat people with HIV is safe for sexually active HIV-negative women to use every day over an extended period, suggest results of a clinical trial of tenofovir topical gel.

27 Feb 2008

Experimental anti-HIV gel is safe for women to use on a daily basis

An experimental anti-HIV gel is safe for women to use on a daily basis, according to researchers at the University of Alabama at Birmingham (UAB) and the University of Pittsburgh School of Medicine.

26 Feb 2008

New large-scale method reveals drug targets

Wellcome Trust Sanger Institute scientists have developed a new large-scale method to identify the interactions between proteins that are a major target for therapeutic intervention.

26 Feb 2008