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Healthy aging modulates the neural oscillatory dynamics serving working memory function

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, "Age-related alterations in the oscillatory dynamics serving verbal working memory processing."

2 Jan 2024

68Ga-FAPI PET imaging superior to existing methods for detecting pancreatic cancer

PET imaging with 68Ga-FAPI can more effectively detect and stage pancreatic cancer as compared with 18F-FDG imaging or contrast-enhanced CT, according to new research published in the December issue of The Journal of Nuclear Medicine.

2 Jan 2024

Scripps scientists develop powerful method to find drug targets in live cells

Identifying new ways to target proteins involved in human diseases is a priority for many researchers around the world.

2 Jan 2024

Novel PET tracer accurately detects common cancer mutation for tailored treatment

A novel PET imaging tracer has been proven to safely and effectively detect a common cancer gene mutation that is an important molecular marker for tumor-targeted therapy.

2 Jan 2024

Understanding acylspermidines' secrets could lead to treatments for various diseases

In a significant advancement in the field of biochemistry, scientists at the Boyce Thompson Institute (BTI) and Cornell University have uncovered new insights into a family of metabolites, acylspermidines, that could change how we understand aging and fight diseases.

2 Jan 2024

Brain receptor discovery opens door to new therapies for addiction and mental health

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders.

2 Jan 2024

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

Throughout the day and night, cerebrospinal fluid (CSF) pulses through small fluid-filled channels surrounding blood vessels in the brain, called perivascular spaces, to flush out neuroinflammation and other neurological waste.

2 Jan 2024

New research highlights potential of cytisine for global smoking cessation efforts

A new study published in Addiction has found that cytisine, a low-cost, generic stop-smoking aid that has been used in eastern Europe since the 1960s, increases the chances of successful smoking cessation by more than two-fold compared with placebo and may be more effective than nicotine replacement therapy. It has a benign safety profile, with no evidence of serious safety concerns.

2 Jan 2024

New ultrasound technology shows promise for preventing brain damage in premature and sick infants

Ultrasound technology developed at the Norwegian University of Science and Technology (NTNU) makes it possible to monitor cerebral blood flow in newborn babies, helping prevent brain damage in premature and sick infants who require surgery.

2 Jan 2024

Healthy fats from fish and nuts may slow lung scarring, delay transplants

Could healthy fats found in nuts and fish slow the progression of potentially deadly lung scarring known as pulmonary fibrosis and delay the need for lung transplants?

2 Jan 2024

Adolescent obesity heightens the risk of early chronic kidney disease in young adulthood

New study finds that adolescent obesity significantly heightens the risk of developing early chronic kidney disease in young adulthood. Even those with high-normal BMI are at risk.

2 Jan 2024

Small molecule-switchable RNA platform enables control of therapeutic protein expression

Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a therapeutic window.

2 Jan 2024

Study reveals burnout and professional dissatisfaction driving physicians to leave their practices

Study investigates the prevalence of burnout, professional fulfillment, and intention to leave among physicians, revealing significant variations based on gender, age, race, and specialty.

1 Jan 2024

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University) and Dr. Xuguang Du (College of Biological Sciences, China Agricultural University) and illustrated the key role of Mettl3 in CD8 T cell response during acute infection model.

29 Dec 2023

Johns Hopkins researchers find minimal regret after gender affirming surgery

In a Viewpoint article published Dec. 27, 2023, in JAMA Surgery, three Johns Hopkins researchers urge the medical community to dismiss a widely held, but scientifically unsupported belief that many people who are transgender and gender diverse (TGD), and undergo gender affirming surgery (GAS), later regret their decision to undergo such procedures.

28 Dec 2023

'Visual system' protein appears to be key for stabilizing the body's circadian rhythms

Scientists at the Johns Hopkins University School of Medicine and the National Institutes of Health have identified a protein in the visual system of mice that appears to be key for stabilizing the body's circadian rhythms by buffering the brain's response to light.

28 Dec 2023

$15 million NCI grant awarded to investigate a type of radiation therapy for hard-to-treat cancers

The Radiopharmaceutical Therapy and Dosimetry Lab at Johns Hopkins Medicine, headed by George Sgouros, Ph.D., has been awarded a $15 million grant, to be dispersed over the next five years, from the National Cancer Institute at the National Institutes of Health.

28 Dec 2023

Angelica gigas extract emerges as a potential treatment for vascular disease

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction."

28 Dec 2023

New insights on better diagnosis and treatment of ischemic cholecystitis

Ischemic cholecystitis is a form of gallbladder inflammation that occurs without gallstones or another form of external compression.

28 Dec 2023

AI advances could revolutionize hepatocellular carcinoma diagnosis

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. It is a major global health concern with rising rates, particularly in North Africa and East Asia.

28 Dec 2023

Medicine News and Research

Healthy aging modulates the neural oscillatory dynamics serving working memory function

68Ga-FAPI PET imaging superior to existing methods for detecting pancreatic cancer

Scripps scientists develop powerful method to find drug targets in live cells

Novel PET tracer accurately detects common cancer mutation for tailored treatment

Understanding acylspermidines' secrets could lead to treatments for various diseases

Brain receptor discovery opens door to new therapies for addiction and mental health

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

New research highlights potential of cytisine for global smoking cessation efforts

New ultrasound technology shows promise for preventing brain damage in premature and sick infants

Healthy fats from fish and nuts may slow lung scarring, delay transplants

Adolescent obesity heightens the risk of early chronic kidney disease in young adulthood

Small molecule-switchable RNA platform enables control of therapeutic protein expression

Study reveals burnout and professional dissatisfaction driving physicians to leave their practices

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

Johns Hopkins researchers find minimal regret after gender affirming surgery

'Visual system' protein appears to be key for stabilizing the body's circadian rhythms

$15 million NCI grant awarded to investigate a type of radiation therapy for hard-to-treat cancers

Angelica gigas extract emerges as a potential treatment for vascular disease

New insights on better diagnosis and treatment of ischemic cholecystitis

AI advances could revolutionize hepatocellular carcinoma diagnosis

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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