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Research reveals why Black women experience higher breast cancer mortality

New research from Sanford Burnham Prebys has revealed significant molecular differences between the breast cells of white and Black women that help explain why Black women experience higher breast cancer mortality.

9 Feb 2022

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies

Researchers have investigated the lack of response to treatment in certain multiple sclerosis patients.

9 Feb 2022

Research findings provide a potential roadmap for metastatic tumor formation

Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types.

9 Feb 2022

Innate immune specificity is driven by the nervous system, study suggests

Research led by Washington State University scientists supports a novel theory that the innate immune system people are born with can respond differently to specific pathogens.

9 Feb 2022

Scientists identify a new protein that prevents cancer cell migration

When tumors spread, cancer cells migrate to other parts of the body through the blood or lymphatic vessels. Scientists at the Institute of Science and Technology Austria have now found a new protein that prevents cancer cells from doing so by making them stick more tightly to their surroundings.

9 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Study explores adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants post-immunization in cancer patients

Researchers have conducted a prospective, longitudinal cohort study to analyze COVID-19 immunity in patients with cancer.

9 Feb 2022

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Drugs which are commonly-used as the first line of treatment for colorectal cancer cause the tumor cells to oversecrete proteins known as mucins, according to a new study published today in the journal eLife.

9 Feb 2022

Antarctic soil sample from 2018 adds to the enigma of the COVID-19 pandemic

The origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has long been debated among scientists. However, prior research found early genetic material of a unique SARS-CoV-2 variant from the soil on King George Island, Antarctica between 24 December 2018 and 13th January 2019.

9 Feb 2022

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

8 Feb 2022

Defective mitochondrial DNA could be modified using gene-editing techniques

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

8 Feb 2022

Study shows how gut bacteria could undermine immunity in pancreatic cancer

Researchers at the University of Toronto and University Health Network have shown how probiotic bacteria in the gut could undermine immunity in pancreatic cancer, pointing toward more personalized cancer treatments.

8 Feb 2022

The B and T cell responses to SARS-CoV-2

Researchers assess the correlation between humoral and cell-mediated responses to SARS-CoV-2 in symptomatic and asymptomatic individuals.

8 Feb 2022

NIH grant renewal will enable Nebraska scientist to advance research on virtual immune system

The renewal of a National Institutes of Health grant will enable a University of Nebraska-Lincoln researcher to continue developing a tool that illuminates the complex, multi-scale interplay of the immune system's many components.

8 Feb 2022

Mechanical hearts can generate new muscle tissue in the failing human heart

Mechanical hearts spur some regeneration in dormant parts of failing hearts, according to a UT Southwestern pilot study that shows promise for developing regenerative heart therapies.

8 Feb 2022

Antibody drug improves survival rates in canine prostate cancer model

Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research.

8 Feb 2022

VANTAstar Microplate Reader from BMG LABTECH

The CLARIOstar® Plus is the most-sensitive monochromator-based microplate reader.

From BMG LABTECH GmbH 8 Feb 2022

VANTAstar Microplate Reader from BMG LABTECH

The VANTAstar® is a compact microplate reader conceived for ease-of-use and flexibility.

From BMG LABTECH GmbH 8 Feb 2022

Using sugar molecules for in vivo tracking of unlabeled stem cells

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers - made out of sugars - that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Researchers demonstrated that an MVA vector expressing the SARS-CoV-2 spike protein was 100% effective in preventing neuroinvasion and brain damage by SARS-CoV-2 in transgenic mice.

8 Feb 2022