Infectious Diseases News and Research

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Only two per cent of 700 paediatric drug trials included independent safety checks

Only two per cent of paediatric drug trials reported that they had established independent safety monitoring committees that can help lead to the early detection of adverse drug reactions, according to a major review in the April issue of Acta Paediatrica.

19 Mar 2008

Discovery alters long standing concept of fixed protein structure

The thousands of proteins found in nature are simply strings of amino acids, assembled by genes, and scientists have long believed that they automatically fold themselves into uniquely fixed, 3-dimensional shapes to fire the engine of life.

19 Mar 2008

Severe West Nile infection could lead to lifetime of symptoms

Most people who suffer severe infection with West Nile virus still experience symptoms years after infection and many may continue to experience these symptoms for the rest of their lives according to research presented (March 17) at the 2008 International Conference on Emerging Infectious Diseases in Atlanta, Georgia.

18 Mar 2008

Scientists identify potential therapy targets for schistosomiasis

A research team supported by the National Institutes of Health (NIH) Roadmap and the National Institute of Allergy and Infectious Diseases (NIAID) has identified chemical compounds that hold promise as potential therapies for schistosomiasis, a parasitic disease that afflicts more than 200 million people worldwide.

18 Mar 2008

Researchers develop method to rapidly ID optimal drug cocktails

UCLA researchers have developed a feedback control scheme that can search for the most effective drug combinations to treat a variety of conditions, including cancers and infections.

18 Mar 2008

New understanding of rare immune disorder called Job's syndrome

Scientists have made another major breakthrough--the second in the past year--in understanding a rare immune disorder called Job's syndrome.

18 Mar 2008

Foodborne outbreaks due to leafy green consumption on the increase

Over the past 35 years the proportion of foodborne outbreaks linked to the consumption of leafy green vegetables has substantially increased and that increase can not be completely attributed to Americans eating more salads according to research presented today (March 17) at the 2008 International Conference on Emerging Infectious Diseases in Atlanta, Georgia.

18 Mar 2008

Discovery of chemical compounds that hold promise as potential therapies for schistosomiasis

17 Mar 2008

New chemical can kill latent tuberculosis bacteria

Success in the laboratory suggests that a new compound can point the way to preventing active tuberculosis in people infected with the latent form of the bacterium, says a team led by researchers at Weill Cornell Medical College in New York City.

17 Mar 2008

Study confirms link between colds and ear infections

A new five-year study at the University of Texas Medical Branch at Galveston confirms the suspected close link between the two most common diseases of young children: colds and ear infections.

14 Mar 2008

Researchers find cause of severe allergic reaction to cetuximab

Clinicians have been perplexed by the fact that some patients given the drug cetuximab - an immune-based therapy commonly used to treat persons diagnosed with head and neck cancer, or colon cancer - have a severe and rapid adverse reaction to the drug.

13 Mar 2008

Aerosol vaccine provides low-cost, needle-free TB treatment

A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental animals than a comparable dose of the traditional injected vaccine, researchers report this week in the Proceedings of the National Academy of Sciences.

13 Mar 2008

Anadis licenses antibody technologies from ImmuCell

Anadis Limited, an Australian-based biotechnology company focused on milk derived polyclonal antibodies and other milk-derived bioactives, announced today that it had signed a final agreement with ImmuCell Corporation, a biotechnology company headquartered in Portland, Maine, USA.

11 Mar 2008

Regenstrief Institute to tackle catastrophic disease outbreaks on behalf of CDC

The Centers for Disease Control has awarded the Indiana University School of Medicine a $2.6 million initial contract with the possibility of nearly $10 million in funding over 5 years to accelerate the real-time ability of local, state and regional entities to share data and information to enhance rapid response to and management of potentially catastrophic infectious disease outbreaks and other public health emergencies.

11 Mar 2008

A simulated pandemic influenza outbreak in Chicago

By using computer simulations and modeling, an international group of researchers including scientists from the Virginia Bioinformatics Institute (VBI) at Virginia Tech's Network Dynamics and Simulation Science Laboratory (NDSSL) have determined how a pandemic influenza outbreak might travel through a city similar in size to Chicago, Ill.

11 Mar 2008

How do infections and toxins launch a cell's self-destruct and alarm system?

Cells are coded with several programs for self-destruction.

11 Mar 2008

Tackling antimicrobial resistance

Drug resistance is making many diseases increasingly difficult and sometimes impossible to treat, according to Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

11 Mar 2008

Japanese find way to make flu vaccine effective for multiple strains

Japanese scientists say they are well on the way to developing influenza vaccines which are effective for multiple strains of the disease, including strains of the bird flu virus.

11 Mar 2008

Pandemic influenza could be mitigated if measures were implemented quickly

An outbreak of pandemic influenza in the U.S. could be mitigated with prompt implementation of social-distancing measures combined with antiviral treatment and prophylaxis until a vaccine is available, according to new findings published in the online Early Edition of PNAS.

10 Mar 2008

London School of Hygiene and Tropical Medicine receives new Gates funding to fight disease

The London School of Hygiene & Tropical Medicine (LSHTM) has been awarded grant funding totalling $46.4 million from the Bill and Melinda Gates Foundation (BMGF) and $12.7 million from other partners, to help find new and effective ways of treating and preventing malaria, tuberculosis (TB) and HIV/AIDS.

10 Mar 2008